Protein Concepts Dictionary

Tableau information

Concept source:  d2we2a2  amino acid (a.a.) range (GLY178)(TYR216)

nSSEs in this Concept: 4

String of secondary struct.elems. (SSEs) defining this concept: EEEE

Each SSE's a.a.range: (start resi) (end resi) SSEtype (H=Helix; E=Strand) followed by a numeric SSE ID:
	  (GLY178)  (CYS184) E1
	  (GLY189)  (SER199) E2
	  (GLN201)  (LYS207) E3
	  (PHE211)  (TYR216) E4

Orientation angles° of SSE-pairs; those in contact shown in bold font
          E1                          
E2      155.7°   E2                   
E3      -54.3°  148.1°   E3            
E4      -28.0°  137.4°  -60.3°       
Footnote: Inferred from this concept's usages (listed below) was the angular variance of 1σ = ±13.0°  about each orientation angle shown above.

Loci of concept usages (shown as a range of a.a. residue ids) in SCOP(v2.05) domains, along with their brief legend taken from SCOP
 d2bsya1 :    (PRO67)  (ALA107)   [view usage] : b.85.4.1 |beta-clip |dUTPase-like |dUTPase-like |Monomeric viral dUTPase |Epstein-Barr virus [TaxId: 10376]
 d2octa_ :    (GLY50)   (ASN88)   [view usage] : d.17.1.2 |Cystatin-like |Cystatin/monellin |Cystatins |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1js4a2 :   (ILE463)  (GLU507)   [view usage] : b.2.2.2 |Common fold of diphtheria toxin/transcription factors/cytochrome f |Carbohydrate-binding domain |Cellulose-binding domain family III |Endo/exocellulase:cellobiose E-4, C-terminal domain |Thermobifida fusca [TaxId: 2021]
 d3rf1a_ :   (HIS106)  (GLY146)   [view usage] : d.104.1.1 |Class II aaRS and biotin synthetases |Class II aaRS and biotin synthetases |Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain |automated matches |Campylobacter jejuni [TaxId: 354242]
 d1e54a_ :   (ASP268)  (PHE332)   [view usage] : f.4.3.1 |Transmembrane beta-barrels |Porins |Porin |Porin |Comamonas acidovorans [TaxId: 80866]
 d1wv3a1 :     (LYS3)   (LYS36)   [view usage] : b.26.1.4 |SMAD/FHA domain |SMAD/FHA domain |EssC N-terminal domain-like |Protein EssC |Staphylococcus aureus [TaxId: 1280]
 d2hmga_ :   (GLU280)  (LYS310)   [view usage] : b.19.1.2 |Viral protein domain |Viral protein domain |Influenza hemagglutinin headpiece |Hemagglutinin |Influenza A virus, different strains [TaxId: 11320]
 d4unwa_ :   (GLU280)  (ARG310)   [view usage] : b.19.1.2 |Viral protein domain |Viral protein domain |Influenza hemagglutinin headpiece |automated matches |Influenza a virus (a/eq/newmarket/93/(h3n8)) [TaxId: 159470]
 d1cpna_ :   (ILE121)  (GLY177)   [view usage] : b.29.1.2 |Concanavalin A-like lectins/glucanases |Concanavalin A-like lectins/glucanases |Glycosyl hydrolases family 16 |Bacillus 1-3,1-4-beta-glucanase |Bacillus macerans [TaxId: 44252]
 d2bwob_ :    (ASP25)   (CYS52)   [view usage] : c.67.1.4 |PLP-dependent transferase-like |PLP-dependent transferases |GABA-aminotransferase-like |automated matches |Rhodobacter capsulatus [TaxId: 1061]
 d1lqtb1 :   (LEU272)  (PRO314)   [view usage] : c.3.1.1 |FAD/NAD(P)-binding domain |FAD/NAD(P)-binding domain |C-terminal domain of adrenodoxin reductase-like |Ferredoxin:NADP reductase FprA |Mycobacterium tuberculosis [TaxId: 1773]
 d2rsda_ :   (LYS114)  (ASP149)   [view usage] : g.50.1.0 |FYVE/PHD zinc finger |FYVE/PHD zinc finger |automated matches |automated matches |Oryza sativa [TaxId: 39947]
 d2ylkb_ :     (ASP1)   (GLU46)   [view usage] : b.2.2.0 |Common fold of diphtheria toxin/transcription factors/cytochrome f |Carbohydrate-binding domain |automated matches |automated matches |Clostridium thermocellum [TaxId: 1515]
 d1w8xh_ :   (SER255)  (PHE291)   [view usage] : i.6.1.1 |Viruses and virus-receptor complexes |Viruses and virus-receptor complexes |Viruses and virus-receptor complexes |PRD1 capsid assembly |Bacteriophage PRD1 [TaxId: 10658]
 d2b29a_ :    (ILE24)   (ALA59)   [view usage] : b.40.4.3 |OB-fold |Nucleic acid-binding proteins |Single strand DNA-binding domain, SSB |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d2k4wa_ :     (ALA1)   (ALA39)   [view usage] : b.1.8.1 |Immunoglobulin-like beta-sandwich |Cu,Zn superoxide dismutase-like |Cu,Zn superoxide dismutase-like |automated matches |Salmonella enterica [TaxId: 119912]
 d3vj7a_ :    (ASP70)  (GLY111)   [view usage] : d.243.1.2 |Colicin D/E5 nuclease domain |Colicin D/E5 nuclease domain |Colicin E5 nuclease domain |Colicin E5 |Escherichia coli [TaxId: 562]
 d3zqxa_ :     (ASP1)   (TYR42)   [view usage] : b.2.2.0 |Common fold of diphtheria toxin/transcription factors/cytochrome f |Carbohydrate-binding domain |automated matches |automated matches |Clostridium thermocellum [TaxId: 1515]
 d1lsla1 :   (ASP417)  (ASP469)   [view usage] : g.60.1.1 |TSP-1 type 1 repeat |TSP-1 type 1 repeat |TSP-1 type 1 repeat |Thrombospondin-1 (TSP-1) |Human (Homo sapiens) [TaxId: 9606]
 d3f4fc_ :    (ASN75)  (LEU117)   [view usage] : b.85.4.0 |beta-clip |dUTPase-like |automated matches |automated matches |Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]
 d3svaa_ :    (VAL50)  (ASP119)   [view usage] : d.17.1.2 |Cystatin-like |Cystatin/monellin |Cystatins |Cystatin C |Human (Homo sapiens) [TaxId: 9606]
 d4gv8d_ :    (HIS72)  (GLU146)   [view usage] : b.85.4.0 |beta-clip |dUTPase-like |automated matches |automated matches |Staphylococcus phage [TaxId: 12360]
 d2we2a1 :    (PRO67)  (ALA107)   [view usage] : b.85.4.1 |beta-clip |dUTPase-like |dUTPase-like |automated matches |Human herpesvirus 4 [TaxId: 10377]
 d3zpyb_ :   (PHE249)  (ASP281)   [view usage] : b.29.1.0 |Concanavalin A-like lectins/glucanases |Concanavalin A-like lectins/glucanases |automated matches |automated matches |Zobellia galactanivorans [TaxId: 63186]
 d2ic2b_ :   (SER464)  (ARG503)   [view usage] : b.1.2.1 |Immunoglobulin-like beta-sandwich |Fibronectin type III |Fibronectin type III |Hedgehog receptor iHog |Fruit fly (Drosophila melanogaster) [TaxId: 7227]
 d1w8xa_ :   (SER255)  (PHE291)   [view usage] : i.6.1.1 |Viruses and virus-receptor complexes |Viruses and virus-receptor complexes |Viruses and virus-receptor complexes |PRD1 capsid assembly |Bacteriophage PRD1 [TaxId: 10658]
 d3cckb_ :   (GLY144)  (GLY169)   [view usage] : d.169.1.1 |C-type lectin-like |C-type lectin-like |C-type lectin domain |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1ms0a1 :   (GLY515)  (MET541)   [view usage] : b.29.1.15 |Concanavalin A-like lectins/glucanases |Concanavalin A-like lectins/glucanases |Trypanosoma sialidase, C-terminal domain |Trypanosoma sialidase, C-terminal domain |Trypanosoma cruzi [TaxId: 5693]
 d2hsta_ :   (SER144)  (PRO177)   [view usage] : c.55.4.2 |Ribonuclease H-like motif |Translational machinery components |ERF1/Dom34 middle domain-like |Middle domain of eukaryotic peptide chain release factor subunit 1, ERF1 |Human (Homo sapiens) [TaxId: 9606]
 d4b9ca_ :     (HIS3)   (TYR45)   [view usage] : b.2.2.0 |Common fold of diphtheria toxin/transcription factors/cytochrome f |Carbohydrate-binding domain |automated matches |automated matches |Clostridium thermocellum [TaxId: 203119]
 d2g2nc_ :     (LEU6)   (PHE66)   [view usage] : b.3.4.0 |Prealbumin-like |Transthyretin (synonym: prealbumin) |automated matches |automated matches |Escherichia coli [TaxId: 562]
 d1lgqa_ :    (TRP16)   (SER52)   [view usage] : b.26.1.2 |SMAD/FHA domain |SMAD/FHA domain |FHA domain |Cell cycle checkpoint protein Chfr |Human (Homo sapiens) [TaxId: 9606]
 d3hhqf_ :    (GLY76)  (LEU117)   [view usage] : b.85.4.0 |beta-clip |dUTPase-like |automated matches |automated matches |Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]
 d2djha_ :    (ASP70)  (GLY111)   [view usage] : d.243.1.2 |Colicin D/E5 nuclease domain |Colicin D/E5 nuclease domain |Colicin E5 nuclease domain |automated matches |Escherichia coli [TaxId: 562]
 d3gmwb_ :    (SER40)   (THR77)   [view usage] : d.98.1.0 |BLIP-like |beta-lactamase-inhibitor protein, BLIP |automated matches |automated matches |Streptomyces exfoliatus [TaxId: 1905]
 d1ms5a1 :   (GLY515)  (MET541)   [view usage] : b.29.1.15 |Concanavalin A-like lectins/glucanases |Concanavalin A-like lectins/glucanases |Trypanosoma sialidase, C-terminal domain |Trypanosoma sialidase, C-terminal domain |Trypanosoma cruzi [TaxId: 5693]
 d4bboc_ :     (ASN4)   (ALA35)   [view usage] : b.61.1.0 |Streptavidin-like |Avidin/streptavidin |automated matches |automated matches |Bradyrhizobium japonicum [TaxId: 375]
 d3r6ba2 :   (ASN492)  (ILE540)   [view usage] : g.60.1.1 |TSP-1 type 1 repeat |TSP-1 type 1 repeat |TSP-1 type 1 repeat |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1wcsa1 :   (GLY519)  (LEU545)   [view usage] : b.29.1.15 |Concanavalin A-like lectins/glucanases |Concanavalin A-like lectins/glucanases |Trypanosoma sialidase, C-terminal domain |Trypanosoma sialidase, C-terminal domain |Trypanosoma rangeli [TaxId: 5698]
 d4q14a_ :     (LEU4)   (HIS67)   [view usage] : b.3.4.0 |Prealbumin-like |Transthyretin (synonym: prealbumin) |automated matches |automated matches |Brucella melitensis [TaxId: 359391]
 d4c8xa_ :     (ASP1)   (GLU46)   [view usage] : b.2.2.0 |Common fold of diphtheria toxin/transcription factors/cytochrome f |Carbohydrate-binding domain |automated matches |automated matches |Clostridium thermocellum [TaxId: 203119]
 d4gnia2 :   (ILE206)  (TYR238)   [view usage] : c.55.1.0 |Ribonuclease H-like motif |Actin-like ATPase domain |automated matches |automated matches |Chaetomium thermophilum [TaxId: 759272]
 d1gw7a_ :  (SER1255) (PHE1291)   [view usage] : i.6.1.1 |Viruses and virus-receptor complexes |Viruses and virus-receptor complexes |Viruses and virus-receptor complexes |p3 shell |Bacteriophage PRD1 [TaxId: 10658]
 d4ogxa_ :   (VAL444)  (THR496)   [view usage] : b.47.1.2 |Trypsin-like serine proteases |Trypsin-like serine proteases |Eukaryotic proteases |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1fa3a_ :    (TYR58)   (PRO92)   [view usage] : d.17.1.1 |Cystatin-like |Cystatin/monellin |Monellin |Monellin, B & A chains together |Serendipity berry (Dioscoreophyllum cumminsii) [TaxId: 3457]
 d2xbta_ :     (ASP9)   (TYR49)   [view usage] : b.2.2.0 |Common fold of diphtheria toxin/transcription factors/cytochrome f |Carbohydrate-binding domain |automated matches |automated matches |Bacteroides cellulosolvens [TaxId: 35825]
 d1mr5a1 :   (GLY515)  (MET541)   [view usage] : b.29.1.15 |Concanavalin A-like lectins/glucanases |Concanavalin A-like lectins/glucanases |Trypanosoma sialidase, C-terminal domain |Trypanosoma sialidase, C-terminal domain |Trypanosoma cruzi [TaxId: 5693]
 d4uo0e_ :   (GLU280)  (ARG310)   [view usage] : b.19.1.2 |Viral protein domain |Viral protein domain |Influenza hemagglutinin headpiece |automated matches |Influenza a virus (a/equine/richmond/1/2007)(h3n8)) [TaxId: 560387]
 d1t6ca1 :     (PRO7)   (ILE42)   [view usage] : c.55.1.8 |Ribonuclease H-like motif |Actin-like ATPase domain |Ppx/GppA phosphatase |Exopolyphosphatase Ppx |Aquifex aeolicus [TaxId: 63363]
 d1ti2a2 :     (GLU3)   (ALA36)   [view usage] : c.81.1.1 |Formate dehydrogenase/DMSO reductase, domains 1-3 |Formate dehydrogenase/DMSO reductase, domains 1-3 |Formate dehydrogenase/DMSO reductase, domains 1-3 |Transhydroxylase alpha subunit, AthL |Pelobacter acidigallici [TaxId: 35816]
 d2ylka_ :     (ASP1)   (TYR42)   [view usage] : b.2.2.0 |Common fold of diphtheria toxin/transcription factors/cytochrome f |Carbohydrate-binding domain |automated matches |automated matches |Clostridium thermocellum [TaxId: 1515]
 d3azbi_ :   (GLY186)  (LEU228)   [view usage] : d.38.1.6 |Thioesterase/thiol ester dehydrase-isomerase |Thioesterase/thiol ester dehydrase-isomerase |FabZ-like |(3R)-hydroxymyristoyl ACP dehydrase FabZ |Malaria parasite (Plasmodium falciparum) [TaxId: 5833]
 d1gw8a_ :  (SER1255) (PHE1291)   [view usage] : i.6.1.1 |Viruses and virus-receptor complexes |Viruses and virus-receptor complexes |Viruses and virus-receptor complexes |p3 shell |Bacteriophage PRD1 [TaxId: 10658]
 d4b96a_ :     (SER1)   (TYR44)   [view usage] : b.2.2.0 |Common fold of diphtheria toxin/transcription factors/cytochrome f |Carbohydrate-binding domain |automated matches |automated matches |Clostridium clariflavum [TaxId: 288965]
 d2bt1a1 :    (VAL68)  (ARG110)   [view usage] : b.85.4.1 |beta-clip |dUTPase-like |dUTPase-like |Monomeric viral dUTPase |Epstein-Barr virus [TaxId: 10376]
 d4gnib2 :   (ILE206)  (TYR238)   [view usage] : c.55.1.0 |Ribonuclease H-like motif |Actin-like ATPase domain |automated matches |automated matches |Chaetomium thermophilum [TaxId: 759272]
 d3r6ba1 :   (ASP435)  (ASP487)   [view usage] : g.60.1.0 |TSP-1 type 1 repeat |TSP-1 type 1 repeat |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1gt8a3 :   (PHE390)  (LYS430)   [view usage] : c.3.1.1 |FAD/NAD(P)-binding domain |FAD/NAD(P)-binding domain |C-terminal domain of adrenodoxin reductase-like |Dihydropyrimidine dehydrogenase, domain 3 |Pig (Sus scrofa) [TaxId: 9823]
 d2we0a1 :    (PRO67)  (ALA107)   [view usage] : b.85.4.1 |beta-clip |dUTPase-like |dUTPase-like |automated matches |Human herpesvirus 4 [TaxId: 10377]

List of distinct SCOP folds where this concept is used (in one or more of its domains):
  c.67,    b.19,    c.81,    b.29,    b.47,     i.6,     f.4,    b.40,   d.104,    c.55,   d.169,     b.2,    b.85,     b.1,    d.17,    d.98,    d.38,    b.26,     c.3,    b.61,  
b.3, g.50, d.243, g.60