Protein Concepts Dictionary

Tableau information

Concept source:  d2gqra_  amino acid (a.a.) range (ALA12)(ASP44)

nSSEs in this Concept: 4

String of secondary struct.elems. (SSEs) defining this concept: EEEE

Each SSE's a.a.range: (start resi) (end resi) SSEtype (H=Helix; E=Strand) followed by a numeric SSE ID:
	   (ALA12)   (SER17) E1
	   (ASP22)   (PHE28) E2
	   (ASN30)   (GLY35) E3
	   (ARG39)   (ASP44) E4

Orientation angles° of SSE-pairs; those in contact shown in bold font
          E1                          
E2      154.5°   E2                   
E3      122.3°  -79.0°   E3            
E4      -72.8°   92.2°  156.8°       
Footnote: Inferred from this concept's usages (listed below) was the angular variance of 1σ = ±13.0°  about each orientation angle shown above.

Loci of concept usages (shown as a range of a.a. residue ids) in SCOP(v2.05) domains, along with their brief legend taken from SCOP
 d2zhra_ :    (LEU84)  (LYS107)   [view usage] : b.50.1.2 |Acid proteases |Acid proteases |Pepsin-like |beta-secretase (memapsin) |Human (Homo sapiens) [TaxId: 9606]
 d1hpga_ :   (VAL167)  (GLY192)   [view usage] : b.47.1.1 |Trypsin-like serine proteases |Trypsin-like serine proteases |Prokaryotic proteases |Glutamic acid-specific protease |Streptomyces griseus [TaxId: 1911]
 d3urfa_ :   (THR243)  (GLY279)   [view usage] : b.22.1.1 |TNF-like |TNF-like |TNF-like |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d2uzxa2 :   (GLU241)  (ILE271)   [view usage] : b.1.18.0 |Immunoglobulin-like beta-sandwich |E set domains |automated matches |automated matches |Listeria monocytogenes [TaxId: 169963]
 d1fjgl_ :    (ARG41)   (GLY72)   [view usage] : b.40.4.5 |OB-fold |Nucleic acid-binding proteins |Cold shock DNA-binding domain-like |Ribosomal protein S12 |Thermus thermophilus [TaxId: 274]
 d41bia_ :    (LEU69)  (SER114)   [view usage] : b.42.1.2 |beta-Trefoil |Cytokine |Interleukin-1 (IL-1) |Interleukin-1beta |Human (Homo sapiens) [TaxId: 9606]
 d1ivoa3 :   (LEU243)  (LYS269)   [view usage] : g.3.9.1 |Knottins (small inhibitors, toxins, lectins) |Growth factor receptor domain |Growth factor receptor domain |EGF receptor Cys-rich domains |Human (Homo sapiens) [TaxId: 9606]
 d1fl7d_ :     (ILE8)   (CYS51)   [view usage] : g.17.1.4 |Cystine-knot cytokines |Cystine-knot cytokines |Gonadodropin/Follitropin |Follicle stimulating hormone, follitropin, beta chain |Human (Homo sapiens) [TaxId: 9606]
 d2au7a_ :    (ASN54)   (ARG86)   [view usage] : b.40.5.1 |OB-fold |Inorganic pyrophosphatase |Inorganic pyrophosphatase |Inorganic pyrophosphatase |Escherichia coli [TaxId: 562]
 d1f1xa2 :   (PHE254)  (ASN286)   [view usage] : d.32.1.3 |Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase |Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase |Extradiol dioxygenases |Homoprotocatechuate 2,3-dioxygenase |Brevibacterium fuscum [TaxId: 47914]
 d4jysa_ :    (ASP76)  (GLU101)   [view usage] : d.26.1.0 |FKBP-like |FKBP-like |automated matches |automated matches |Plasmodium vivax [TaxId: 126793]
 d4jysa_ :   (ILE104)  (GLN139)   [view usage] : d.26.1.0 |FKBP-like |FKBP-like |automated matches |automated matches |Plasmodium vivax [TaxId: 126793]
 d2rmpa_ :    (ASP94)  (GLY116)   [view usage] : b.50.1.2 |Acid proteases |Acid proteases |Pepsin-like |Acid protease |Rhizomucor miehei [TaxId: 4839]
 d1l3aa_ :   (PRO112)  (SER154)   [view usage] : d.18.1.2 |ssDNA-binding transcriptional regulator domain |ssDNA-binding transcriptional regulator domain |Plant transcriptional regulator PBF-2 |Plant transcriptional regulator PBF-2 |Potato (Solanum tuberosum) [TaxId: 4113]
 d4mqwb_ :     (ILE8)   (CYS51)   [view usage] : g.17.1.4 |Cystine-knot cytokines |Cystine-knot cytokines |Gonadodropin/Follitropin |Follicle stimulating hormone, follitropin, beta chain |Human (Homo sapiens) [TaxId: 9606]
 d1eqqa_ :    (LEU83)  (LEU112)   [view usage] : b.40.4.3 |OB-fold |Nucleic acid-binding proteins |Single strand DNA-binding domain, SSB |ssDNA-binding protein |Escherichia coli [TaxId: 562]
 d1e4eb2 :   (CYS213)  (PRO261)   [view usage] : d.142.1.1 |ATP-grasp |Glutathione synthetase ATP-binding domain-like |ATP-binding domain of peptide synthetases |D-alanine:D-lactate ligase VanA, C-domain |Enterococcus faecium [TaxId: 1352]
 d1i1qa_ :    (ALA34)   (ALA72)   [view usage] : d.161.1.1 |ADC synthase |ADC synthase |ADC synthase |Anthranilate synthase aminodeoxyisochorismate synthase/lyase subunit, TrpE |Salmonella typhimurium [TaxId: 90371]
 d3keba_ :     (ASP3)   (PHE29)   [view usage] : c.47.1.0 |Thioredoxin fold |Thioredoxin-like |automated matches |automated matches |Chromobacterium violaceum [TaxId: 536]
 d3be1a2 :   (LEU249)  (THR275)   [view usage] : g.3.9.0 |Knottins (small inhibitors, toxins, lectins) |Growth factor receptor domain |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1eqqd_ :   (LEU683)  (LEU712)   [view usage] : b.40.4.3 |OB-fold |Nucleic acid-binding proteins |Single strand DNA-binding domain, SSB |ssDNA-binding protein |Escherichia coli [TaxId: 562]
 d1vpka1 :    (GLY40)   (PHE68)   [view usage] : d.131.1.1 |DNA clamp |DNA clamp |DNA polymerase III, beta subunit |DNA polymerase III, beta subunit |Thermotoga maritima [TaxId: 2336]
 d2omza1 :   (TRP417)  (THR446)   [view usage] : b.1.18.15 |Immunoglobulin-like beta-sandwich |E set domains |Internalin Ig-like domain |Internalin A |Listeria monocytogenes [TaxId: 1639]
 d1slia2 :   (LEU418)  (HIS462)   [view usage] : b.68.1.1 |6-bladed beta-propeller |Sialidases |Sialidases (neuraminidases) |Leech intramolecular trans-sialidase, C-terminal domain |North american leech (Macrobdella decora) [TaxId: 6405]
 d1zunb2 :   (MSE338)  (PRO363)   [view usage] : b.44.1.1 |Elongation factor/aminomethyltransferase common domain |EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain |EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain |Sulfate adenylate transferase subunit cysN/C, EF-Tu domain 3-like domain |Pseudomonas syringae pv. tomato [TaxId: 323]
 d2d1za2 :   (LEU366)  (GLY400)   [view usage] : b.42.2.0 |beta-Trefoil |Ricin B-like lectins |automated matches |automated matches |Streptomyces olivaceoviridis [TaxId: 1921]
 d1iu4a_ :   (ASN239)  (GLY275)   [view usage] : d.3.1.8 |Cysteine proteinases |Cysteine proteinases |Microbial transglutaminase |Microbial transglutaminase |Streptoverticillium mobaraense [TaxId: 35621]
 d4kqqa1 :   (ARG193)  (LEU221)   [view usage] : d.175.1.0 |Penicillin binding protein dimerisation domain |Penicillin binding protein dimerisation domain |automated matches |automated matches |Pseudomonas aeruginosa [TaxId: 208964]
 d3nuaa_ :    (ALA13)   (GLU45)   [view usage] : d.143.1.0 |SAICAR synthase-like |SAICAR synthase-like |automated matches |automated matches |Clostridium perfringens [TaxId: 195103]
 d1kv7a1 :    (GLY55)   (GLN81)   [view usage] : b.6.1.3 |Cupredoxin-like |Cupredoxins |Multidomain cupredoxins |multi-copper oxidase CueO |Escherichia coli [TaxId: 562]
 d4eeua_ :   (THR452)  (GLN489)   [view usage] : d.110.3.6 |Profilin-like |PYP-like sensor domain (PAS domain) |Flavin-binding PAS domain |automated matches |Thale cress (Arabidopsis thaliana) [TaxId: 3702]
 d2cu5a_ :    (VAL92)  (LEU128)   [view usage] : d.273.1.0 |YjbQ-like |YjbQ-like |automated matches |automated matches |Thermus thermophilus HB8 [TaxId: 300852]
 d1m9sa1 :   (GLU241)  (ILE271)   [view usage] : b.1.18.15 |Immunoglobulin-like beta-sandwich |E set domains |Internalin Ig-like domain |Internalin B |Listeria monocytogenes [TaxId: 1639]
 d2cu5b_ :    (VAL92)  (LEU128)   [view usage] : d.273.1.0 |YjbQ-like |YjbQ-like |automated matches |automated matches |Thermus thermophilus HB8 [TaxId: 300852]
 d1eqqb_ :   (LEU283)  (LEU312)   [view usage] : b.40.4.3 |OB-fold |Nucleic acid-binding proteins |Single strand DNA-binding domain, SSB |ssDNA-binding protein |Escherichia coli [TaxId: 562]
 d2o5fb_ :     (GLU7)   (ARG52)   [view usage] : d.113.1.2 |Nudix |Nudix |IPP isomerase-like |Hypothetical protein DR0079 |Deinococcus radiodurans str. R1 (Deinococcus radiodurans R1) [TaxId: 243230]
 d1sddb4 :  (THR2113) (PHE2150)   [view usage] : b.18.1.2 |Galactose-binding domain-like |Galactose-binding domain-like |Discoidin domain (FA58C, coagulation factor 5/8 C-terminal domain) |C2 domain of factor V |Cow (Bos taurus) [TaxId: 9913]
 d2imld_ :    (GLY11)   (LYS46)   [view usage] : b.45.1.4 |Split barrel-like |FMN-binding split barrel |MTH863-like |Hypothetical protein AF1834 |Archaeoglobus fulgidus [TaxId: 2234]
 d4iyaa_ :    (GLY52)   (ASN93)   [view usage] : f.6.1.0 |Leukocidin-like |Leukocidin-like |automated matches |automated matches |Staphylococcus phage [TaxId: 71366]
 d2x4mc_ :   (TRP199)  (PHE242)   [view usage] : f.4.4.0 |Transmembrane beta-barrels |OMPT-like |automated matches |automated matches |Yersinia pestis [TaxId: 632]
 d3l60a_ :   (ASN237)  (VAL272)   [view usage] : c.43.1.0 |CoA-dependent acyltransferases |CoA-dependent acyltransferases |automated matches |automated matches |Mycobacterium tuberculosis [TaxId: 1773]
 d1eo8a_ :    (PRO21)   (ASN54)   [view usage] : b.19.1.2 |Viral protein domain |Viral protein domain |Influenza hemagglutinin headpiece |Hemagglutinin |Influenza A virus, different strains [TaxId: 11320]
 d117ea_ :    (GLN98)  (THR131)   [view usage] : b.40.5.1 |OB-fold |Inorganic pyrophosphatase |Inorganic pyrophosphatase |Inorganic pyrophosphatase |Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]
 d1zsob_ :    (HIS-1)   (ASN41)   [view usage] : b.166.1.1 |MAL13P1.257-like |MAL13P1.257-like |MAL13P1.257-like |Hypothetical protein MAL13P1.257 |Malaria parasite (Plasmodium falciparum) [TaxId: 5833]
 d1zsoa1 :     (THR4)   (ASN41)   [view usage] : b.166.1.1 |MAL13P1.257-like |MAL13P1.257-like |MAL13P1.257-like |Hypothetical protein MAL13P1.257 |Malaria parasite (Plasmodium falciparum) [TaxId: 5833]
 d3hhqf_ :    (GLN37)   (ILE65)   [view usage] : b.85.4.0 |beta-clip |dUTPase-like |automated matches |automated matches |Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]
 d4tw1d_ :    (GLY85)  (ASP127)   [view usage] : f.6.1.0 |Leukocidin-like |Leukocidin-like |automated matches |automated matches |Staphylococcus aureus [TaxId: 451516]
 d2imla1 :    (GLY11)   (LYS46)   [view usage] : b.45.1.4 |Split barrel-like |FMN-binding split barrel |MTH863-like |Hypothetical protein AF1834 |Archaeoglobus fulgidus [TaxId: 2234]
 d1mqla_ :    (PRO21)   (ASN54)   [view usage] : b.19.1.2 |Viral protein domain |Viral protein domain |Influenza hemagglutinin headpiece |Hemagglutinin |Influenza A virus, different strains [TaxId: 11320]
 d2viua_ :    (PRO21)   (PRO55)   [view usage] : b.19.1.2 |Viral protein domain |Viral protein domain |Influenza hemagglutinin headpiece |Hemagglutinin |Influenza A virus, different strains [TaxId: 11320]
 d3u01a_ :    (TYR64)  (GLY100)   [view usage] : d.5.1.1 |RNase A-like |RNase A-like |Ribonuclease A-like |automated matches |Frog (Rana pipiens) [TaxId: 8404]
 d1ssna_ :    (ALA85)  (LYS136)   [view usage] : d.15.5.1 |beta-Grasp (ubiquitin-like) |Staphylokinase/streptokinase |Staphylokinase/streptokinase |Staphylokinase |Staphylococcus aureus [TaxId: 1280]
 d2imlb_ :    (GLY11)   (LYS46)   [view usage] : b.45.1.4 |Split barrel-like |FMN-binding split barrel |MTH863-like |Hypothetical protein AF1834 |Archaeoglobus fulgidus [TaxId: 2234]
 d2o5fa_ :     (GLU7)   (ARG52)   [view usage] : d.113.1.2 |Nudix |Nudix |IPP isomerase-like |Hypothetical protein DR0079 |Deinococcus radiodurans str. R1 (Deinococcus radiodurans R1) [TaxId: 243230]
 d2q11a_ :    (ASP83)  (LYS107)   [view usage] : b.50.1.2 |Acid proteases |Acid proteases |Pepsin-like |beta-secretase (memapsin) |Human (Homo sapiens) [TaxId: 9606]
 d1dp4a_ :   (VAL391)  (VAL420)   [view usage] : c.93.1.1 |Periplasmic binding protein-like I |Periplasmic binding protein-like I |L-arabinose binding protein-like |Hormone binding domain of the atrial natriuretic peptide receptor |Norway rat (Rattus norvegicus) [TaxId: 10116]
 d3d03a_ :   (HIS217)  (GLN251)   [view usage] : d.159.1.11 |Metallo-dependent phosphatases |Metallo-dependent phosphatases |GpdQ-like |Glycerophosphodiesterase GpdQ |Enterobacter aerogenes [TaxId: 548]
 d2rbla_ :   (ILE833)  (PHE889)   [view usage] : b.1.2.1 |Immunoglobulin-like beta-sandwich |Fibronectin type III |Fibronectin type III |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d3c0da1 :    (GLU66)  (GLU111)   [view usage] : b.33.1.3 |ISP domain |ISP domain |NirD-like |NADH-nitrite reductase small subunit NirD |Vibrio parahaemolyticus [TaxId: 670]
 d1vkza3 :   (LEU185)  (GLY224)   [view usage] : d.142.1.2 |ATP-grasp |Glutathione synthetase ATP-binding domain-like |BC ATP-binding domain-like |Glycinamide ribonucleotide synthetase (GAR-syn), domain 2 |Thermotoga maritima [TaxId: 2336]
 d3vmfa3 :   (PRO345)  (ILE387)   [view usage] : b.44.1.0 |Elongation factor/aminomethyltransferase common domain |EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain |automated matches |automated matches |Aeropyrum pernix [TaxId: 272557]
 d2ox7a1 :    (ASP37)   (GLN69)   [view usage] : b.172.1.1 |YopX-like |YopX-like |YopX-like |Hypothetical protein EF1440 |Enterococcus faecalis [TaxId: 1351]
 d1mcoh2 :   (SER119)  (SER157)   [view usage] : b.1.1.2 |Immunoglobulin-like beta-sandwich |Immunoglobulin |C1 set domains (antibody constant domain-like) |Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma |Human (Homo sapiens) [TaxId: 9606]
 d1p4ta_ :    (LEU88)  (TYR132)   [view usage] : f.4.1.1 |Transmembrane beta-barrels |OMPA-like |Outer membrane protein |Outer membrane protein NspA |Neisseria meningitidis [TaxId: 487]
 d2zjph1 :    (HIS79)  (GLY112)   [view usage] : b.39.1.1 |Ribosomal protein L14 |Ribosomal protein L14 |Ribosomal protein L14 |Ribosomal protein L14 |Deinococcus radiodurans [TaxId: 1299]
 d3bn6a_ :    (THR71)  (ASP106)   [view usage] : b.18.1.0 |Galactose-binding domain-like |Galactose-binding domain-like |automated matches |automated matches |Cow (Bos taurus) [TaxId: 9913]
 d3bzma_ :    (TRP95)  (LEU123)   [view usage] : d.161.1.1 |ADC synthase |ADC synthase |ADC synthase |automated matches |Escherichia coli [TaxId: 562]
 d1wcdj1 :   (TYR214)  (THR250)   [view usage] : b.121.4.9 |Nucleoplasmin-like/VP (viral coat and capsid proteins) |Positive stranded ssRNA viruses |Birnaviridae-like VP |Birnavirus VP2 |Infectious bursal disease virus [TaxId: 10995]
 d2ox5a_ :     (ALA4)   (ILE47)   [view usage] : b.1.18.0 |Immunoglobulin-like beta-sandwich |E set domains |automated matches |automated matches |Paracoccus denitrificans [TaxId: 266]

List of distinct SCOP folds where this concept is used (in one or more of its domains):
  b.68,    b.19,   d.159,    b.47,    c.93,    b.50,     f.4,    b.40,    c.47,    b.18,   b.121,     d.3,     b.6,    b.85,    d.32,     b.1,    b.45,   d.110,    c.43,   d.143,  
b.42, d.142, d.131, d.273, b.22, d.5, d.15, d.175, d.113, d.26, g.17, b.33, b.44, f.6, d.161, d.18, g.3, b.172, b.166, b.39