Protein Concepts Dictionary

Tableau information

Concept source:  d3iweb1  amino acid (a.a.) range (PHE225)(PHE247)

nSSEs in this Concept: 4

String of secondary struct.elems. (SSEs) defining this concept: EEEE

Each SSE's a.a.range: (start resi) (end resi) SSEtype (H=Helix; E=Strand) followed by a numeric SSE ID:
	  (PHE225)  (PRO230) E1
	  (ASN232)  (TYR236) E2
	  (ASP237)  (LYS241) E3
	  (LYS241)  (PHE247) E4

Orientation angles° of SSE-pairs; those in contact shown in bold font
          E1                          
E2      -75.2°   E2                   
E3     -120.0°  160.7°   E3            
E4      155.9°  103.1°  -68.1°       
Footnote: Inferred from this concept's usages (listed below) was the angular variance of 1σ = ±10.2°  about each orientation angle shown above.

Loci of concept usages (shown as a range of a.a. residue ids) in SCOP(v2.05) domains, along with their brief legend taken from SCOP
 d1ebfa2 :   (ASN282)  (ASP306)   [view usage] : d.81.1.2 |FwdE/GAPDH domain-like |Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain |Homoserine dehydrogenase-like |Homoserine dehydrogenase |Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]
 d1e8vb_ :   (ARG485)  (SER508)   [view usage] : b.68.1.1 |6-bladed beta-propeller |Sialidases |Sialidases (neuraminidases) |Paramyxovirus hemagglutinin-neuraminidase head domain |Newcastle disease virus [TaxId: 11176]
 d1fjra_ :   (TYR163)  (CYS185)   [view usage] : b.102.1.1 |Methuselah ectodomain |Methuselah ectodomain |Methuselah ectodomain |Methuselah ectodomain |Fruit fly (Drosophila melanogaster) [TaxId: 7227]
 d2rhba2 :   (THR274)  (LEU297)   [view usage] : d.294.1.2 |EndoU-like |EndoU-like |Nsp15 C-terminal domain-like |Nsp15, C-terminal domain |SARS coronavirus [TaxId: 227859]
 d1i19a2 :    (ASP69)   (LYS95)   [view usage] : d.145.1.1 |FAD-binding/transporter-associated domain-like |FAD-binding/transporter-associated domain-like |FAD-linked oxidases, N-terminal domain |Cholesterol oxidase |Brevibacterium sterolicum [TaxId: 1702]
 d1xpna_ :    (GLY43)   (GLU70)   [view usage] : b.3.7.1 |Prealbumin-like |Hypothetical protein PA1324 |Hypothetical protein PA1324 |Hypothetical protein PA1324 |Pseudomonas aeruginosa [TaxId: 287]
 d3mr1b_ :   (ASN158)  (ASN205)   [view usage] : d.127.1.0 |Creatinase/aminopeptidase |Creatinase/aminopeptidase |automated matches |automated matches |Rickettsia prowazekii [TaxId: 782]
 d2r7da2 :   (GLU168)  (LYS196)   [view usage] : b.40.4.16 |OB-fold |Nucleic acid-binding proteins |RNB domain-like |Ribonuclease II family protein DR0020 |Deinococcus radiodurans [TaxId: 1299]
 d2x4ma_ :   (ASP187)  (GLY232)   [view usage] : f.4.4.0 |Transmembrane beta-barrels |OMPT-like |automated matches |automated matches |Yersinia pestis [TaxId: 632]
 d1xhxa2 :   (GLY549)  (ILE574)   [view usage] : e.8.1.1 |DNA/RNA polymerases |DNA/RNA polymerases |DNA polymerase I |phi29 DNA polymerase |Bacteriophage phi-29 [TaxId: 10756]
 d1slia2 :   (ASN465)  (ASN490)   [view usage] : b.68.1.1 |6-bladed beta-propeller |Sialidases |Sialidases (neuraminidases) |Leech intramolecular trans-sialidase, C-terminal domain |North american leech (Macrobdella decora) [TaxId: 6405]
 d2gina_ :    (LYS81)  (THR107)   [view usage] : b.159.1.1 |AOC barrel-like |Allene oxide cyclase-like |Allene oxide cyclase-like |Allene oxide cyclase, AOC |Thale cress (Arabidopsis thaliana), chloroplast AOC2 [TaxId: 3702]
 d1mr6a_ :     (MET1)   (THR63)   [view usage] : g.7.1.1 |Snake toxin-like |Snake toxin-like |Snake venom toxins |Bungarotoxin |Many-banded krait (Bungarus multicinctus), gamma-bungarotoxin [TaxId: 8616]
 d3qrdc_ :    (VAL60)  (VAL104)   [view usage] : d.17.1.2 |Cystatin-like |Cystatin/monellin |Cystatins |Cystatin C |Human (Homo sapiens) [TaxId: 9606]
 d4keha_ :   (ILE139)  (LEU164)   [view usage] : d.38.1.2 |Thioesterase/thiol ester dehydrase-isomerase |Thioesterase/thiol ester dehydrase-isomerase |beta-Hydroxydecanol thiol ester dehydrase |beta-Hydroxydecanol thiol ester dehydrase |Escherichia coli [TaxId: 562]
 d1ntya2 :  (ILE1428) (GLU1454)   [view usage] : b.55.1.1 |PH domain-like barrel |PH domain-like |Pleckstrin-homology domain (PH domain) |Triple functional domain protein TRIO |Human (Homo sapiens) [TaxId: 9606]
 d3mr1a_ :   (ASN158)  (ASN205)   [view usage] : d.127.1.0 |Creatinase/aminopeptidase |Creatinase/aminopeptidase |automated matches |automated matches |Rickettsia prowazekii [TaxId: 782]
 d1naqc_ :    (ALA38)   (LEU66)   [view usage] : d.58.5.2 |Ferredoxin-like |GlnB-like |Divalent ion tolerance proteins CutA (CutA1) |Cut A1 |Escherichia coli [TaxId: 562]
 d1fmba_ :    (GLU61)   (ASP84)   [view usage] : b.50.1.1 |Acid proteases |Acid proteases |Retroviral protease (retropepsin) |EIAV protease |Equine infectious anemia virus [TaxId: 11665]
 d1cb8a3 :   (ASN534)  (ILE567)   [view usage] : b.30.5.2 |Supersandwich |Galactose mutarotase-like |Hyaluronate lyase-like, central domain |Chondroitinase AC |Pedobacter heparinus (Flavobacterium heparinum) [TaxId: 984]
 d2wnre1 :   (ASP164)  (PRO186)   [view usage] : d.14.1.0 |Ribosomal protein S5 domain 2-like |Ribosomal protein S5 domain 2-like |automated matches |automated matches |Methanothermobacter thermautotrophicus [TaxId: 145262]
 d3mwza_ :    (GLY57)  (ASN100)   [view usage] : d.17.1.0 |Cystatin-like |Cystatin/monellin |automated matches |automated matches |Ixodes scapularis [TaxId: 6945]
 d2gtha2 :   (SER302)  (LEU325)   [view usage] : d.294.1.2 |EndoU-like |EndoU-like |Nsp15 C-terminal domain-like |Nsp15, C-terminal domain |Murine hepatitis virus, MHV [TaxId: 11138]
 d1ig0a1 :   (GLU258)  (SER278)   [view usage] : b.82.6.1 |Double-stranded beta-helix |Thiamin pyrophosphokinase, substrate-binding domain |Thiamin pyrophosphokinase, substrate-binding domain |Thiamin pyrophosphokinase, substrate-binding domain |Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]
 d2oolb1 :   (TRP191)  (PRO213)   [view usage] : d.110.2.1 |Profilin-like |GAF domain-like |GAF domain |Sensor protein PhyB2 |Rhodopseudomonas palustris [TaxId: 1076]
 d1yela1 :    (PRO35)   (GLY58)   [view usage] : b.142.1.2 |DNA-binding pseudobarrel domain |DNA-binding pseudobarrel domain |B3 DNA binding domain |At1g16640 |Thale cress (Arabidopsis thaliana) [TaxId: 3702]
 d3q62b_ :   (ILE140)  (LYS167)   [view usage] : d.38.1.2 |Thioesterase/thiol ester dehydrase-isomerase |Thioesterase/thiol ester dehydrase-isomerase |beta-Hydroxydecanol thiol ester dehydrase |automated matches |Yersinia pseudotuberculosis [TaxId: 214092]
 d4l1pb_ :   (GLY407)  (ARG429)   [view usage] : b.34.21.1 |SH3-like barrel |Plus3-like |Plus3 |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1w26a3 :   (ASP162)  (ALA188)   [view usage] : d.26.1.1 |FKBP-like |FKBP-like |FKBP immunophilin/proline isomerase |Trigger factor PPIase domain |Escherichia coli [TaxId: 562]
 d4kehb_ :   (ILE139)  (LEU164)   [view usage] : d.38.1.2 |Thioesterase/thiol ester dehydrase-isomerase |Thioesterase/thiol ester dehydrase-isomerase |beta-Hydroxydecanol thiol ester dehydrase |beta-Hydroxydecanol thiol ester dehydrase |Escherichia coli [TaxId: 562]
 d3u1ua_ :   (GLY407)  (ARG429)   [view usage] : b.34.21.1 |SH3-like barrel |Plus3-like |Plus3 |RNA polymerase-associated protein RTF1 homolog |Human (Homo sapiens) [TaxId: 9606]
 d2h85a2 :   (THR274)  (LEU297)   [view usage] : d.294.1.2 |EndoU-like |EndoU-like |Nsp15 C-terminal domain-like |Nsp15, C-terminal domain |SARS coronavirus [TaxId: 227859]
 d1g0va_ :    (GLY78)  (PRO108)   [view usage] : b.50.1.2 |Acid proteases |Acid proteases |Pepsin-like |Acid protease |Baker's yeast (Saccharomyces cerevisiae), proteinase A [TaxId: 4932]
 d1t11a3 :   (GLY161)  (GLU188)   [view usage] : d.26.1.1 |FKBP-like |FKBP-like |FKBP immunophilin/proline isomerase |Trigger factor PPIase domain |Vibrio cholerae [TaxId: 666]
 d2kl2a_ :    (GLY32)   (GLU69)   [view usage] : d.269.1.1 |Gamma-glutamyl cyclotransferase-like |Gamma-glutamyl cyclotransferase-like |Gamma-glutamyl cyclotransferase-like |Hypothetical protein LOC223267 |Mouse (Mus musculus) [TaxId: 10090]
 d1wq9b_ :    (VAL59)   (MET86)   [view usage] : g.17.1.1 |Cystine-knot cytokines |Cystine-knot cytokines |Platelet-derived growth factor-like |Vascular endothelial growth factor, VEGF |Russell's viper (Daboia russelli russelli) [TaxId: 8707]
 d2pl5a1 :     (GLY8)   (GLY39)   [view usage] : c.69.1.40 |alpha/beta-Hydrolases |alpha/beta-Hydrolases |O-acetyltransferase |Homoserine O-acetyltransferase |Leptospira interrogans [TaxId: 173]
 d4wjka_ :   (ASP301)  (PRO331)   [view usage] : b.69.8.0 |7-bladed beta-propeller |Integrin alpha N-terminal domain |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]

List of distinct SCOP folds where this concept is used (in one or more of its domains):
  b.68,     e.8,    b.82,    c.69,    d.58,    b.69,    b.30,    b.50,     f.4,    b.40,    d.14,    d.81,   d.127,   d.108,   d.110,    d.17,    d.38,    b.55,    b.34,   d.145,  
b.3, d.26, g.17, g.7, b.102, b.159, d.294, b.142, d.269