Protein Concepts Dictionary

Tableau information

Concept source:  d1c5md_  amino acid (a.a.) range (ARG63)(LEU108)

nSSEs in this Concept: 4

String of secondary struct.elems. (SSEs) defining this concept: EEEE

Each SSE's a.a.range: (start resi) (end resi) SSEtype (H=Helix; E=Strand) followed by a numeric SSE ID:
	   (ARG63)   (GLY69) E1
	   (GLU80)   (GLU84) E2
	   (GLU86)   (HIS91) E3
	  (ASP102)  (LEU108) E4

Orientation angles° of SSE-pairs; those in contact shown in bold font
          E1                          
E2      148.7°   E2                   
E3       98.1°  -79.6°   E3            
E4      -77.1°   96.3°  163.7°       
Footnote: Inferred from this concept's usages (listed below) was the angular variance of 1σ = ±12.1°  about each orientation angle shown above.

Loci of concept usages (shown as a range of a.a. residue ids) in SCOP(v2.05) domains, along with their brief legend taken from SCOP
 d1gl4a1 :   (SER400)  (THR445)   [view usage] : d.22.1.2 |GFP-like |GFP-like |Domain G2 of nidogen-1 |Domain G2 of nidogen-1 |Mouse (Mus musculus) [TaxId: 10090]
 d1kjza2 :   (LYS350)  (LYS377)   [view usage] : b.44.1.1 |Elongation factor/aminomethyltransferase common domain |EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain |EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain |Initiation factor eIF2 gamma subunit |Pyrococcus abyssi [TaxId: 29292]
 d4m7ga_ :    (ASP51)   (THR93)   [view usage] : b.47.1.0 |Trypsin-like serine proteases |Trypsin-like serine proteases |automated matches |automated matches |Saccharopolyspora erythraea [TaxId: 1836]
 d2ynaa_ :    (ILE17)   (PRO39)   [view usage] : b.47.1.0 |Trypsin-like serine proteases |Trypsin-like serine proteases |automated matches |automated matches |Tylonycteris bat coronavirus hku4 [TaxId: 694007]
 d1s0ua2 :   (GLY377)  (LEU407)   [view usage] : b.44.1.1 |Elongation factor/aminomethyltransferase common domain |EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain |EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain |Initiation factor eIF2 gamma subunit |Methanococcus jannaschii [TaxId: 2190]
 d4aa9a_ :    (GLY18)   (SER44)   [view usage] : b.50.1.2 |Acid proteases |Acid proteases |Pepsin-like |automated matches |Camel (Camelus dromedarius) [TaxId: 9838]
 d1t9fa_ :   (LEU105)  (HIS155)   [view usage] : b.42.6.1 |beta-Trefoil |MIR domain |MIR domain |Hypothetical protein R12E2.13 (1D10) |Nematode (Caenorhabditis elegans) [TaxId: 6239]
 d1e0ta1 :    (ILE72)  (SER103)   [view usage] : b.58.1.1 |PK beta-barrel domain-like |PK beta-barrel domain-like |Pyruvate kinase beta-barrel domain |Pyruvate kinase (PK) |Escherichia coli [TaxId: 562]
 d2d04f_ :    (ARG53)   (PRO99)   [view usage] : b.78.1.0 |beta-Prism II |alpha-D-mannose-specific plant lectins |automated matches |automated matches |Curculigo latifolia [TaxId: 4676]
 d2cmba_ :    (ARG56)   (GLN85)   [view usage] : c.45.1.2 |(Phosphotyrosine protein) phosphatases II |(Phosphotyrosine protein) phosphatases II |Higher-molecular-weight phosphotyrosine protein phosphatases |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1n7za_ :   (GLY265)  (PHE334)   [view usage] : b.127.1.1 |Baseplate structural protein gp8 |Baseplate structural protein gp8 |Baseplate structural protein gp8 |Baseplate structural protein gp8 |Bacteriophage T4 [TaxId: 10665]
 d1g90a_ :    (TYR48)   (GLY98)   [view usage] : f.4.1.1 |Transmembrane beta-barrels |OMPA-like |Outer membrane protein |Outer membrane protein A (OMPA) transmembrane domain |Escherichia coli [TaxId: 562]
 d3i78a_ :    (SER63)  (LYS107)   [view usage] : b.47.1.1 |Trypsin-like serine proteases |Trypsin-like serine proteases |Prokaryotic proteases |Trypsin |Streptomyces griseus, strain k1 [TaxId: 1911]
 d2znra_ :   (ILE291)  (ASN327)   [view usage] : c.97.3.1 |Cytidine deaminase-like |JAB1/MPN domain |JAB1/MPN domain |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d4df3a_ :    (GLY15)   (ASN56)   [view usage] : c.66.1.0 |S-adenosyl-L-methionine-dependent methyltransferases |S-adenosyl-L-methionine-dependent methyltransferases |automated matches |automated matches |Aeropyrum pernix [TaxId: 56636]
 d1nh1a_ :   (ASP143)  (ALA181)   [view usage] : e.45.1.1 |Antivirulence factor |Antivirulence factor |Antivirulence factor |Type III effector AvrB |Pseudomonas syringae [TaxId: 317]
 d3op1b2 :   (VAL226)  (ASP260)   [view usage] : b.43.5.0 |Reductase/isomerase/elongation factor common domain |Riboflavin kinase-like |automated matches |automated matches |Pneumococcus (Streptococcus pneumoniae) [TaxId: 1313]
 d2vv6a_ :   (VAL222)  (THR257)   [view usage] : d.110.3.2 |Profilin-like |PYP-like sensor domain (PAS domain) |Heme-binding PAS domain |Histidine kinase FixL heme domain |Bradyrhizobium japonicum [TaxId: 375]
 d1ogmx2 :   (THR349)  (PRO378)   [view usage] : b.80.1.10 |Single-stranded right-handed beta-helix |Pectin lyase-like |Dextranase, catalytic domain |Dextranase, catalytic domain |Penicillium minioluteum [TaxId: 28574]
 d3zpyb_ :   (THR294)  (GLU345)   [view usage] : b.29.1.0 |Concanavalin A-like lectins/glucanases |Concanavalin A-like lectins/glucanases |automated matches |automated matches |Zobellia galactanivorans [TaxId: 63186]
 d1s66u_ :    (ARG97)  (ASP132)   [view usage] : d.110.3.2 |Profilin-like |PYP-like sensor domain (PAS domain) |Heme-binding PAS domain |Direct oxygen sensor protein, DOS |Escherichia coli [TaxId: 562]
 d1h8ga_ :   (GLY291)  (LYS318)   [view usage] : b.109.1.1 |beta-hairpin stack |Cell wall binding repeat |Cell wall binding repeat |Choline binding domain of autolysin C-LytA |Pneumococcus (Streptococcus pneumoniae) [TaxId: 1313]
 d2ox7b_ :     (PRO5)   (ASP37)   [view usage] : b.172.1.1 |YopX-like |YopX-like |YopX-like |Hypothetical protein EF1440 |Enterococcus faecalis [TaxId: 1351]
 d3h7oa_ :    (THR15)   (THR41)   [view usage] : b.47.1.0 |Trypsin-like serine proteases |Trypsin-like serine proteases |automated matches |automated matches |Sarcoptes scabiei [TaxId: 197185]
 d1wjqa_ :    (LYS17)   (PHE48)   [view usage] : b.34.9.3 |SH3-like barrel |Tudor/PWWP/MBT |MBT repeat |Lethal(3)malignant brain tumor-like 3 protein, L3MBTL3 (KIAA1798) |Human (Homo sapiens) [TaxId: 9606]
 d1qa7b_ :    (MET54)   (PRO91)   [view usage] : b.47.1.4 |Trypsin-like serine proteases |Trypsin-like serine proteases |Viral cysteine protease of trypsin fold |3C cysteine protease (picornain 3C) |Human hepatitis A virus [TaxId: 208726]
 d1vs5l1 :    (VAL62)   (GLY99)   [view usage] : b.40.4.5 |OB-fold |Nucleic acid-binding proteins |Cold shock DNA-binding domain-like |Ribosomal protein S12 |Escherichia coli [TaxId: 562]
 d2hafa1 :    (ASN20)   (ASN55)   [view usage] : d.310.1.1 |VC0467-like |VC0467-like |VC0467-like |Hypothetical protein VC0467 |Vibrio cholerae [TaxId: 666]
 d2z77d_ :    (VAL94)  (TRP128)   [view usage] : d.17.4.3 |Cystatin-like |NTF2-like |Ketosteroid isomerase-like |Hypothetical protein Rv0760c |Mycobacterium tuberculosis H37Rv [TaxId: 83332]
 d2aj7b_ :    (VAL91)  (ASP130)   [view usage] : b.158.1.1 |BH3618-like |BH3618-like |BH3618-like |Hypothetical protein BH3618 |Bacillus halodurans [TaxId: 86665]
 d2cmza1 :   (GLY202)  (PRO232)   [view usage] : e.76.1.2 |Viral glycoprotein ectodomain-like |Viral glycoprotein ectodomain-like |Spike glycoprotein-like |Spike glycoprotein |Vesicular stomatitis indiana virus [TaxId: 11277]
 d3tloa_ :    (ASN64)   (VAL90)   [view usage] : b.47.1.4 |Trypsin-like serine proteases |Trypsin-like serine proteases |Viral cysteine protease of trypsin fold |Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) |Human coronavirus [TaxId: 443239]
 d2a15a1 :    (ILE92)  (TRP128)   [view usage] : d.17.4.3 |Cystatin-like |NTF2-like |Ketosteroid isomerase-like |Hypothetical protein Rv0760c |Mycobacterium tuberculosis [TaxId: 1773]
 d2dfka2 :   (MET272)  (LYS298)   [view usage] : b.55.1.1 |PH domain-like barrel |PH domain-like |Pleckstrin-homology domain (PH domain) |Rho guanine nucleotide exchange factor 9, Collybistin |Norway rat (Rattus norvegicus) [TaxId: 10116]
 d2ox7c_ :     (PRO5)   (ASP37)   [view usage] : b.172.1.1 |YopX-like |YopX-like |YopX-like |Hypothetical protein EF1440 |Enterococcus faecalis [TaxId: 1351]
 d1wrua2 :     (THR4)   (PRO41)   [view usage] : b.106.1.1 |Phage tail proteins |Phage tail proteins |Baseplate protein-like |Baseplate protein gpP |Bacteriophage Mu [TaxId: 10677]
 d4ilgc_ :  (ILE2201) (SER2239)   [view usage] : c.97.3.0 |Cytidine deaminase-like |JAB1/MPN domain |automated matches |automated matches |Baker's yeast (Saccharomyces cerevisiae) [TaxId: 559292]
 d1pytc_ :   (TRP429)  (THR454)   [view usage] : b.47.1.2 |Trypsin-like serine proteases |Trypsin-like serine proteases |Eukaryotic proteases |Procarboxypeptidase A-S6 subunit III (zymogen E) |Cow (Bos taurus) [TaxId: 9913]
 d2vh4a_ :   (VAL360)  (LEU420)   [view usage] : e.1.1.0 |Serpins |Serpins |automated matches |automated matches |Thermoanaerobacter tengcongensis [TaxId: 273068]
 d1by3a_ :   (VAL490)  (ALA539)   [view usage] : f.4.3.3 |Transmembrane beta-barrels |Porins |Ligand-gated protein channel |Ferric hydroxamate uptake receptor FhuA |Escherichia coli [TaxId: 562]
 d1eypa_ :     (SER4)   (LEU30)   [view usage] : d.36.1.1 |Chalcone isomerase |Chalcone isomerase |Chalcone isomerase |Chalcone isomerase |Alfalfa (Medicago sativa) [TaxId: 3879]
 d1jx0a_ :     (SER4)   (LEU30)   [view usage] : d.36.1.1 |Chalcone isomerase |Chalcone isomerase |Chalcone isomerase |Chalcone isomerase |Alfalfa (Medicago sativa) [TaxId: 3879]
 d1baia_ :    (ARG10)   (SER46)   [view usage] : b.50.1.1 |Acid proteases |Acid proteases |Retroviral protease (retropepsin) |Rous sarcoma virus protease |Rous sarcoma virus, strain pr-C [TaxId: 11886]
 d2vv6c_ :   (VAL222)  (THR257)   [view usage] : d.110.3.2 |Profilin-like |PYP-like sensor domain (PAS domain) |Heme-binding PAS domain |Histidine kinase FixL heme domain |Bradyrhizobium japonicum [TaxId: 375]
 d1fq3a_ :    (SER61)  (GLN107)   [view usage] : b.47.1.2 |Trypsin-like serine proteases |Trypsin-like serine proteases |Eukaryotic proteases |Granzyme B |Human (Homo sapiens) [TaxId: 9606]
 d1k8wa3 :   (ARG282)  (ARG307)   [view usage] : b.122.1.1 |PUA domain-like |PUA domain-like |PUA domain |Pseudouridine synthase II TruB, C-terminal domain |Escherichia coli [TaxId: 562]
 d2ox7a1 :     (PRO5)   (ASP37)   [view usage] : b.172.1.1 |YopX-like |YopX-like |YopX-like |Hypothetical protein EF1440 |Enterococcus faecalis [TaxId: 1351]
 d1ix5a_ :   (GLY110)  (ASP133)   [view usage] : d.26.1.1 |FKBP-like |FKBP-like |FKBP immunophilin/proline isomerase |Archaeal FKBP |Methanococcus thermolithotrophicus [TaxId: 2186]
 d2wtra1 :   (SER126)  (PRO175)   [view usage] : b.1.18.11 |Immunoglobulin-like beta-sandwich |E set domains |Arrestin/Vps26-like |Arrestin |Cow (Bos taurus), beta-arrestin 1 [TaxId: 9913]
 d2f5ka1 :    (VAL17)   (GLY48)   [view usage] : b.34.13.3 |SH3-like barrel |Chromo domain-like |Chromo barrel domain |Mortality factor 4-like protein 1, MRG15 |Human (Homo sapiens) [TaxId: 9606]
 d1kk0a2 :   (LYS350)  (LYS377)   [view usage] : b.44.1.1 |Elongation factor/aminomethyltransferase common domain |EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain |EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain |Initiation factor eIF2 gamma subunit |Pyrococcus abyssi [TaxId: 29292]
 d2exda1 :   (ILE112)  (ARG139)   [view usage] : b.40.12.1 |OB-fold |NfeD domain-like |NfeD domain-like |Hypothetical protein PH0471 |Pyrococcus horikoshii [TaxId: 53953]
 d3u1jb_ :    (GLU93)  (ALA127)   [view usage] : b.47.1.3 |Trypsin-like serine proteases |Trypsin-like serine proteases |Viral proteases |NS3 protease |Dengue virus 3 [TaxId: 408693]
 d3kmaa_ :    (ASN75)  (ILE103)   [view usage] : b.85.7.2 |beta-clip |SET domain |Viral histone H3 Lysine 27 Methyltransferase |Viral histone H3 Lysine 27 Methyltransferase |Paramecium bursaria chlorella virus 1, PBCV-1 [TaxId: 10506]

List of distinct SCOP folds where this concept is used (in one or more of its domains):
  b.80,    b.29,    b.47,    c.66,    c.45,    b.50,     f.4,    b.40,    b.85,   b.122,     b.1,    c.97,   d.110,    b.42,    d.17,    b.55,     e.1,    b.34,   b.109,    b.43,  
d.26, b.44, e.76, b.106, d.36, b.58, d.310, b.172, d.22, b.78, b.158, e.45, b.127