Tableau information
Concept source: d1b43a1 amino acid (a.a.) range (LEU246)(LEU279)
nSSEs in this Concept: 3
String of secondary struct.elems. (SSEs) defining this concept: HHH
Each SSE's a.a.range: (start resi) (end resi) SSEtype (H=Helix; E=Strand) followed by a numeric SSE ID:
(LEU246) (SER256) H1
(ASP258) (PHE263) H2
(TYR272) (LEU279) H3
Orientation angles° of SSE-pairs; those in contact shown in bold font
H1
H2 121.4° H2
H3 -82.8° 149.3°
Footnote: Inferred from this concept's usages (listed below) was the angular variance of 1σ = ±7.8° about each orientation angle shown above.
Loci of concept usages (shown as a range of a.a. residue ids) in SCOP(v2.05) domains, along with their brief legend taken from SCOP
d1f20a1 : (GLN1133) (LEU1167) [view usage] : b.43.4.1 |Reductase/isomerase/elongation factor common domain |Riboflavin synthase domain-like |NADPH-cytochrome p450 reductase FAD-binding domain-like |Neuronal nitric-oxide synthase FAD/NADP+ domain |Norway rat (Rattus norvegicus) [TaxId: 10116]
d2d48a_ : (ASP62) (SER128) [view usage] : a.26.1.2 |4-helical cytokines |4-helical cytokines |Short-chain cytokines |automated matches |Human (Homo sapiens) [TaxId: 9606]
d3bwya_ : (THR4) (HIS57) [view usage] : c.66.1.1 |S-adenosyl-L-methionine-dependent methyltransferases |S-adenosyl-L-methionine-dependent methyltransferases |COMT-like |Catechol O-methyltransferase, COMT |Human (Homo sapiens) [TaxId: 9606]
d1g3na_ : (ILE262) (GLN301) [view usage] : d.144.1.7 |Protein kinase-like (PK-like) |Protein kinase-like (PK-like) |Protein kinases, catalytic subunit |Cyclin-dependent PK, CDK6 |Human (Homo sapiens) [TaxId: 9606]
d1xm5c_ : (CYS3089) (GLY3145) [view usage] : d.92.1.15 |Zincin-like |Metalloproteases ("zincins"), catalytic domain |Predicted metal-dependent hydrolase |Hypothetical protein YbeY |Escherichia coli [TaxId: 562]
d1orva2 : (HIS592) (ILE624) [view usage] : c.69.1.24 |alpha/beta-Hydrolases |alpha/beta-Hydrolases |DPP6 catalytic domain-like |Dipeptidyl peptidase IV/CD26, C-terminal domain |Pig (Sus scrofa) [TaxId: 9823]
d4bp0a_ : (SER130) (SER163) [view usage] : d.157.1.0 |Metallo-hydrolase/oxidoreductase |Metallo-hydrolase/oxidoreductase |automated matches |automated matches |Pseudomonas aeruginosa [TaxId: 287]
d4oufb_ : (SER1108) (VAL1129) [view usage] : a.29.2.1 |Bromodomain-like |Bromodomain |Bromodomain |CREB-binding protein, CBP |Human (Homo sapiens) [TaxId: 9606]
d1hija_ : (ASP62) (SER128) [view usage] : a.26.1.2 |4-helical cytokines |4-helical cytokines |Short-chain cytokines |Interleukin-4 (IL-4) |Human (Homo sapiens) [TaxId: 9606]
d4fila_ : (ASP129) (LYS172) [view usage] : c.92.2.0 |Chelatase-like |"Helical backbone" metal receptor |automated matches |automated matches |Staphylococcus aureus [TaxId: 1280]
d2ogfa_ : (THR6) (GLN61) [view usage] : d.316.1.0 |MK0786-like |MK0786-like |automated matches |automated matches |Methanocaldococcus jannaschii [TaxId: 2190]
d1zx3a1 : (SER28) (TYR93) [view usage] : a.43.1.6 |Ribbon-helix-helix |Ribbon-helix-helix |NE0241-like |Hypothetical protein NE0241 |Nitrosomonas europaea [TaxId: 915]
d4mhva_ : (ALA77) (GLY133) [view usage] : a.60.1.0 |SAM domain-like |SAM/Pointed domain |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
d2j5ib_ : (ARG198) (ASP249) [view usage] : c.14.1.0 |ClpP/crotonase |ClpP/crotonase |automated matches |automated matches |Pseudomonas fluorescens [TaxId: 294]
d4rc5b_ : (ALA185) (GLY227) [view usage] : a.25.1.6 |Ferritin-like |Ferritin-like |PMT1231-like |automated matches |Synechococcus elongatus [TaxId: 1140]
d2juza1 : (SER8) (ARG72) [view usage] : a.284.1.1 |YejL-like |YejL-like |YejL-like |Uncharacterized protein HI0840 |Haemophilus influenzae [TaxId: 727]
d1pbwa_ : (ALA200) (GLN252) [view usage] : a.116.1.1 |GTPase activation domain, GAP |GTPase activation domain, GAP |BCR-homology GTPase activation domain (BH-domain) |p85 alpha subunit RhoGAP domain |Human (Homo sapiens) [TaxId: 9606]
d1oz9a_ : (SER90) (LYS148) [view usage] : d.92.1.15 |Zincin-like |Metalloproteases ("zincins"), catalytic domain |Predicted metal-dependent hydrolase |Hypothetical protein Aq_1354 |Aquifex aeolicus [TaxId: 63363]
d2jrxb_ : (ASP9) (SER67) [view usage] : a.284.1.1 |YejL-like |YejL-like |YejL-like |Uncharacterized protein YejL |Escherichia coli [TaxId: 562]
d2cl5a_ : (THR4) (GLU56) [view usage] : c.66.1.1 |S-adenosyl-L-methionine-dependent methyltransferases |S-adenosyl-L-methionine-dependent methyltransferases |COMT-like |automated matches |Norway rat (Rattus norvegicus) [TaxId: 10116]
d2yaya_ : (ARG153) (LYS214) [view usage] : a.204.1.0 |all-alpha NTP pyrophosphatases |all-alpha NTP pyrophosphatases |automated matches |automated matches |Leishmania major [TaxId: 5664]
d1r6ea_ : (ASN170) (LEU236) [view usage] : a.168.1.1 |SopE-like GEF domain |SopE-like GEF domain |SopE-like GEF domain |Effector protein SopE2 |Salmonella typhimurium [TaxId: 90371]
d4rc7b_ : (ALA185) (GLY227) [view usage] : a.25.1.6 |Ferritin-like |Ferritin-like |PMT1231-like |automated matches |Synechococcus elongatus [TaxId: 1140]
d2juzb_ : (ASP9) (HIS75) [view usage] : a.284.1.1 |YejL-like |YejL-like |YejL-like |Uncharacterized protein HI0840 |Haemophilus influenzae [TaxId: 727]
d1aora1 : (PHE395) (MET417) [view usage] : a.110.1.1 |Aldehyde ferredoxin oxidoreductase, C-terminal domains |Aldehyde ferredoxin oxidoreductase, C-terminal domains |Aldehyde ferredoxin oxidoreductase, C-terminal domains |Aldehyde ferredoxin oxidoreductase |Pyrococcus furiosus [TaxId: 2261]
d4pyna_ : (THR47) (SER101) [view usage] : c.66.1.1 |S-adenosyl-L-methionine-dependent methyltransferases |S-adenosyl-L-methionine-dependent methyltransferases |COMT-like |Catechol O-methyltransferase, COMT |Norway rat (Rattus norvegicus) [TaxId: 10116]
d1fura_ : (GLY417) (TRP453) [view usage] : a.127.1.1 |L-aspartase-like |L-aspartase-like |L-aspartase/fumarase |Fumarase |Escherichia coli [TaxId: 562]
d1xm5a_ : (CYS1089) (GLY1145) [view usage] : d.92.1.15 |Zincin-like |Metalloproteases ("zincins"), catalytic domain |Predicted metal-dependent hydrolase |Hypothetical protein YbeY |Escherichia coli [TaxId: 562]
d3mdqa2 : (SER239) (MSE271) [view usage] : c.55.1.0 |Ribonuclease H-like motif |Actin-like ATPase domain |automated matches |automated matches |Cytophaga hutchinsonii [TaxId: 269798]
d3pxaa1 : (TYR1716) (GLU1754) [view usage] : c.15.1.3 |BRCT domain |BRCT domain |BRCT domain |Breast cancer associated protein, BRCA1 |Human (Homo sapiens) [TaxId: 9606]
d2bw3a1 : (SER87) (LEU141) [view usage] : a.270.1.1 |Hermes dimerisation domain |Hermes dimerisation domain |Hermes dimerisation domain |Transposase Hermes, dimerisation domain |House fly (Musca domestica) [TaxId: 7370]
d1nx9a2 : (ASN113) (GLY142) [view usage] : c.69.1.21 |alpha/beta-Hydrolases |alpha/beta-Hydrolases |PepX catalytic domain-like |Alpha-amino acid ester hydrolase |Acetobacter pasteurianus [TaxId: 438]
d4a5sb2 : (HIS592) (ILE624) [view usage] : c.69.1.0 |alpha/beta-Hydrolases |alpha/beta-Hydrolases |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
d1e6vb2 : (SER119) (VAL161) [view usage] : d.58.31.2 |Ferredoxin-like |Methyl-coenzyme M reductase subunits |Methyl-coenzyme M reductase alpha and beta chain N-terminal domain |Beta chain |Methanopyrus kandleri [TaxId: 2320]
d2ezka_ : (SER126) (ASP166) [view usage] : a.4.1.2 |DNA/RNA-binding 3-helical bundle |Homeodomain-like |Recombinase DNA-binding domain |Ibeta subdomain of the mu end DNA-binding domain of phage mu transposase |Bacteriophage Mu [TaxId: 10677]
d4nr4a_ : (SER1108) (VAL1129) [view usage] : a.29.2.1 |Bromodomain-like |Bromodomain |Bromodomain |automated matches |Human (Homo sapiens) [TaxId: 9606]
d1h1da_ : (THR4) (TYR57) [view usage] : c.66.1.1 |S-adenosyl-L-methionine-dependent methyltransferases |S-adenosyl-L-methionine-dependent methyltransferases |COMT-like |Catechol O-methyltransferase, COMT |Norway rat (Rattus norvegicus) [TaxId: 10116]
d1t5ja_ : (SER150) (ILE190) [view usage] : a.209.1.1 |ADP-ribosylglycohydrolase |ADP-ribosylglycohydrolase |ADP-ribosylglycohydrolase |Hypothetical protein MJ1187 |Methanococcus jannaschii [TaxId: 2190]
d2vkdb_ : (ARG175) (ASN236) [view usage] : c.68.1.22 |Nucleotide-diphospho-sugar transferases |Nucleotide-diphospho-sugar transferases |Glycosylating toxin catalytic domain-like |automated matches |Clostridium sordellii [TaxId: 1505]
d3pxba1 : (SER1715) (GLU1754) [view usage] : c.15.1.3 |BRCT domain |BRCT domain |BRCT domain |Breast cancer associated protein, BRCA1 |Human (Homo sapiens) [TaxId: 9606]
d3u81a_ : (THR4) (SER58) [view usage] : c.66.1.1 |S-adenosyl-L-methionine-dependent methyltransferases |S-adenosyl-L-methionine-dependent methyltransferases |COMT-like |Catechol O-methyltransferase, COMT |Norway rat (Rattus norvegicus) [TaxId: 10116]
d1mpxa2 : (ASP83) (GLY111) [view usage] : c.69.1.21 |alpha/beta-Hydrolases |alpha/beta-Hydrolases |PepX catalytic domain-like |Alpha-amino acid ester hydrolase |Xanthomonas citri [TaxId: 346]
d2dzda2 : (GLN298) (GLY331) [view usage] : d.142.1.0 |ATP-grasp |Glutathione synthetase ATP-binding domain-like |automated matches |automated matches |Geobacillus thermodenitrificans [TaxId: 33940]
d1jswb_ : (HIS421) (ASP455) [view usage] : a.127.1.1 |L-aspartase-like |L-aspartase-like |L-aspartase/fumarase |L-aspartate ammonia lyase |Escherichia coli [TaxId: 562]
d2jpqb_ : (THR8) (LEU69) [view usage] : a.284.1.1 |YejL-like |YejL-like |YejL-like |Hypothetical protein VP2129 |Vibrio parahaemolyticus [TaxId: 670]
d4jjnh_ : (SER58) (THR128) [view usage] : a.22.1.1 |Histone-fold |Histone-fold |Nucleosome core histones |automated matches |Baker's yeast (Saccharomyces cerevisiae) [TaxId: 559292]
d2c6fb_ : (SER281) (GLY316) [view usage] : d.92.1.0 |Zincin-like |Metalloproteases ("zincins"), catalytic domain |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
d1hs6a3 : (SER290) (THR355) [view usage] : d.92.1.13 |Zincin-like |Metalloproteases ("zincins"), catalytic domain |Zn aminopeptidase catalytic domain |Leukotriene A4 hydrolase catalytic domain |Human (Homo sapiens) [TaxId: 9606]
d1bbna_ : (ASP66) (CYS131) [view usage] : a.26.1.2 |4-helical cytokines |4-helical cytokines |Short-chain cytokines |Interleukin-4 (IL-4) |Human (Homo sapiens) [TaxId: 9606]
d1p28a_ : (GLY64) (SER117) [view usage] : a.39.2.1 |EF Hand-like |Insect pheromone/odorant-binding proteins |Insect pheromone/odorant-binding proteins |Pheromone binding protein PBPLma |Madeira cockroach (Leucophaea maderae) [TaxId: 36963]
d1mbza1 : (ASP401) (ASN440) [view usage] : c.26.2.1 |Adenine nucleotide alpha hydrolase-like |Adenine nucleotide alpha hydrolases-like |N-type ATP pyrophosphatases |beta-Lactam synthetase |Streptomyces clavuligerus [TaxId: 1901]
d1qmga1 : (ASN502) (LYS527) [view usage] : a.100.1.2 |6-phosphogluconate dehydrogenase C-terminal domain-like |6-phosphogluconate dehydrogenase C-terminal domain-like |Acetohydroxy acid isomeroreductase (ketol-acid reductoisomerase, KARI) |Class II ketol-acid reductoisomerase |Spinach (Spinacia oleracea) [TaxId: 3562]
d1tlla1 : (GLN1133) (LEU1167) [view usage] : b.43.4.1 |Reductase/isomerase/elongation factor common domain |Riboflavin synthase domain-like |NADPH-cytochrome p450 reductase FAD-binding domain-like |Neuronal nitric-oxide synthase FAD/NADP+ domain |Norway rat (Rattus norvegicus) [TaxId: 10116]
d1ja1a1 : (GLU411) (LEU447) [view usage] : b.43.4.1 |Reductase/isomerase/elongation factor common domain |Riboflavin synthase domain-like |NADPH-cytochrome p450 reductase FAD-binding domain-like |NADPH-cytochrome p450 reductase |Norway rat (Rattus norvegicus) [TaxId: 10116]
d3c9ua1 : (ARG2) (ASP26) [view usage] : d.79.4.1 |Bacillus chorismate mutase-like |PurM N-terminal domain-like |PurM N-terminal domain-like |Thiamine monophosphate kinase (ThiL) N-terminal domain |Aquifex aeolicus [TaxId: 63363]
d2jssa2 : (SER23) (THR93) [view usage] : a.22.1.1 |Histone-fold |Histone-fold |Nucleosome core histones |Histone H2B |Baker's yeast (Saccharomyces cerevisiae), H2B.2 [TaxId: 4932]
d2aaaa2 : (PHE137) (ASP163) [view usage] : c.1.8.1 |TIM beta/alpha-barrel |(Trans)glycosidases |Amylase, catalytic domain |Fungal alpha-amylases |Aspergillus niger, acid amylase [TaxId: 5061]
d2ejra3 : (ALA712) (PRO741) [view usage] : d.16.1.5 |FAD-linked reductases, C-terminal domain |FAD-linked reductases, C-terminal domain |L-aminoacid/polyamine oxidase |Lysine-specific histone demethylase 1, LSD1 |Human (Homo sapiens) [TaxId: 9606]
d1yhma_ : (PHE116) (SER173) [view usage] : a.128.1.0 |Terpenoid synthases |Terpenoid synthases |automated matches |automated matches |Trypanosoma cruzi [TaxId: 5693]
d3d0ga_ : (VAL293) (ASN330) [view usage] : d.92.1.5 |Zincin-like |Metalloproteases ("zincins"), catalytic domain |Neurolysin-like |Angiotensin converting enzyme 2, ACE2 |Paguma larvata
d2c3ea_ : (SER45) (TRP70) [view usage] : f.42.1.1 |Mitochondrial carrier |Mitochondrial carrier |Mitochondrial carrier |automated matches |Cow (Bos taurus) [TaxId: 9913]
d1wlma1 : (GLY16) (THR58) [view usage] : a.39.1.11 |EF Hand-like |EF-hand |p25-alpha |Protein cgi-38 |Mouse (Mus musculus) [TaxId: 10090]
d2gtqa2 : (GLU393) (GLN438) [view usage] : d.92.1.13 |Zincin-like |Metalloproteases ("zincins"), catalytic domain |Zn aminopeptidase catalytic domain |Aminopeptidase N (APN) catalytic domain |Neisseria meningitidis [TaxId: 122586]
d4rc5a_ : (ALA185) (VAL231) [view usage] : a.25.1.6 |Ferritin-like |Ferritin-like |PMT1231-like |automated matches |Synechococcus elongatus [TaxId: 1140]
d1jexa_ : (GLY42) (LYS72) [view usage] : d.120.1.1 |Cytochrome b5-like heme/steroid binding domain |Cytochrome b5-like heme/steroid binding domain |Cytochrome b5 |Cytochrome b5 |Norway rat (Rattus norvegicus) [TaxId: 10116]
d4c2qa_ : (ASP300) (LYS338) [view usage] : d.92.1.5 |Zincin-like |Metalloproteases ("zincins"), catalytic domain |Neurolysin-like |automated matches |Human (Homo sapiens) [TaxId: 9606]
d4rc7a_ : (ALA185) (ALA230) [view usage] : a.25.1.6 |Ferritin-like |Ferritin-like |PMT1231-like |automated matches |Synechococcus elongatus [TaxId: 1140]
d1faha_ : (GLU143) (TYR198) [view usage] : a.104.1.1 |Cytochrome P450 |Cytochrome P450 |Cytochrome P450 |Cytochrome P450 bm-3 |Bacillus megaterium [TaxId: 1404]
d3scka_ : (VAL293) (ASN330) [view usage] : d.92.1.5 |Zincin-like |Metalloproteases ("zincins"), catalytic domain |Neurolysin-like |Angiotensin converting enzyme 2, ACE2 |Paguma larvata
d2b8xa_ : (ASP62) (SER128) [view usage] : a.26.1.2 |4-helical cytokines |4-helical cytokines |Short-chain cytokines |automated matches |Human (Homo sapiens) [TaxId: 9606]
d2juwa1 : (SER8) (SER71) [view usage] : a.284.1.1 |YejL-like |YejL-like |YejL-like |Uncharacterized protein SO2176 |Shewanella oneidensis [TaxId: 70863]
d1dgja1 : (SER122) (SER166) [view usage] : a.56.1.1 |CO dehydrogenase ISP C-domain like |CO dehydrogenase ISP C-domain like |CO dehydrogenase ISP C-domain like |Aldehyde oxidoreductase, domain 2 |Desulfovibrio desulfuricans [TaxId: 876]
d4gxga_ : (ASN63) (LYS87) [view usage] : a.224.1.1 |Glycolipid transfer protein, GLTP |Glycolipid transfer protein, GLTP |Glycolipid transfer protein, GLTP |Glycolipid transfer protein, GLTP |Human (Homo sapiens) [TaxId: 9606]
d2cm7a_ : (ILE246) (HIS296) [view usage] : c.45.1.2 |(Phosphotyrosine protein) phosphatases II |(Phosphotyrosine protein) phosphatases II |Higher-molecular-weight phosphotyrosine protein phosphatases |Tyrosine phosphatase |Human (Homo sapiens), 1B [TaxId: 9606]
d1la3a_ : (ASN3) (PHE56) [view usage] : a.39.1.5 |EF Hand-like |EF-hand |Calmodulin-like |Recoverin |Cow (Bos taurus) [TaxId: 9913]
d1ocrj_ : (VAL5) (PRO56) [view usage] : f.23.4.1 |Single transmembrane helix |Mitochondrial cytochrome c oxidase subunit VIIa |Mitochondrial cytochrome c oxidase subunit VIIa |Mitochondrial cytochrome c oxidase subunit VIIa |Cow (Bos taurus) [TaxId: 9913]
d1nm8a1 : (GLY59) (SER98) [view usage] : c.43.1.3 |CoA-dependent acyltransferases |CoA-dependent acyltransferases |Choline/Carnitine O-acyltransferase |Carnitine acetyltransferase |Human (Homo sapiens) [TaxId: 9606]
d2b4ka2 : (ASN113) (GLY142) [view usage] : c.69.1.21 |alpha/beta-Hydrolases |alpha/beta-Hydrolases |PepX catalytic domain-like |Alpha-amino acid ester hydrolase |Acetobacter pasteurianus [TaxId: 438]
d1hzia_ : (ASP62) (SER128) [view usage] : a.26.1.2 |4-helical cytokines |4-helical cytokines |Short-chain cytokines |Interleukin-4 (IL-4) |Human (Homo sapiens) [TaxId: 9606]
List of distinct SCOP folds where this concept is used (in one or more of its domains):
c.1, c.69, a.104, d.58, c.68, c.26, a.128, c.92, d.157, c.66, d.92, c.14, c.45, a.127, d.144, c.55, c.43, a.25, d.79, d.142,
a.100, a.4, a.39, b.43, d.16, a.224, a.29, a.116, a.26, d.120, c.15, a.60, a.209, a.56, a.204, a.22, f.23, f.42, a.110, a.284,
a.43, a.168, d.316, a.270