Protein Concepts Dictionary

Tableau information

Concept source:  d1u45a1  amino acid (a.a.) range (LEU396)(ASN468)

nSSEs in this Concept: 3

String of secondary struct.elems. (SSEs) defining this concept: HHH

Each SSE's a.a.range: (start resi) (end resi) SSEtype (H=Helix; E=Strand) followed by a numeric SSE ID:
	  (LEU396)  (ASP402) H1
	  (ASP409)  (GLN418) H2
	  (GLU440)  (ASN468) H3

Orientation angles° of SSE-pairs; those in contact shown in bold font
          H1                   
H2       51.4°   H2            
H3       45.6°   48.1°       
Footnote: Inferred from this concept's usages (listed below) was the angular variance of 1σ = ±12.1°  about each orientation angle shown above.

Loci of concept usages (shown as a range of a.a. residue ids) in SCOP(v2.05) domains, along with their brief legend taken from SCOP
 d4pica_ :   (THR102)  (HIS150)   [view usage] : c.44.1.0 |Phosphotyrosine protein phosphatases I-like |Phosphotyrosine protein phosphatases I |automated matches |automated matches |Geobacillus stearothermophilus [TaxId: 1422]
 d1hjra_ :   (ALA102)  (ASN155)   [view usage] : c.55.3.6 |Ribonuclease H-like motif |Ribonuclease H-like |RuvC resolvase |RuvC resolvase |Escherichia coli [TaxId: 562]
 d4kzoa_ :   (LEU216)  (LYS243)   [view usage] : c.77.1.1 |Isocitrate/Isopropylmalate dehydrogenase-like |Isocitrate/Isopropylmalate dehydrogenase-like |Dimeric isocitrate & isopropylmalate dehydrogenases |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d4c9zb_ :    (CYS98)  (LEU120)   [view usage] : b.8.1.2 |TRAF domain-like |TRAF domain-like |SIAH, seven in absentia homolog |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d3m8ra1 :   (PRO373)  (GLU421)   [view usage] : c.55.3.5 |Ribonuclease H-like motif |Ribonuclease H-like |DnaQ-like 3'-5' exonuclease |Exonuclease domain of prokaryotic DNA polymerase |Thermus aquaticus [TaxId: 271]
 d3wccc_ :    (VAL81)  (GLU115)   [view usage] : a.128.1.0 |Terpenoid synthases |Terpenoid synthases |automated matches |automated matches |Trypanosoma cruzi [TaxId: 353153]
 d1an4a_ :   (HIS204)  (GLN256)   [view usage] : a.38.1.1 |HLH-like |HLH, helix-loop-helix DNA-binding domain |HLH, helix-loop-helix DNA-binding domain |Usf B/HLH domain |Human (Homo sapiens) [TaxId: 9606]
 d2xy8a_ :   (LEU131)  (GLY180)   [view usage] : c.55.3.5 |Ribonuclease H-like motif |Ribonuclease H-like |DnaQ-like 3'-5' exonuclease |automated matches |Escherichia coli [TaxId: 562]
 d2d5ra1 :   (VAL195)  (MET244)   [view usage] : c.55.3.9 |Ribonuclease H-like motif |Ribonuclease H-like |CAF1-like ribonuclease |CCR4-NOT transcription complex subunit 7, CAF1 |Human (Homo sapiens) [TaxId: 9606]
 d1af8a_ :     (THR6)   (ILE38)   [view usage] : a.28.1.1 |Acyl carrier protein-like |ACP-like |Acyl-carrier protein (ACP) |Actinorhodin polyketide synthase acyl carrier protein, ACT ACP |Streptomyces coelicolor, A3(2) [TaxId: 1902]
 d4etna_ :   (THR104)  (LYS147)   [view usage] : c.44.1.0 |Phosphotyrosine protein phosphatases I-like |Phosphotyrosine protein phosphatases I |automated matches |automated matches |Bacillus subtilis [TaxId: 1423]
 d4etma1 :   (ARG110)  (GLN155)   [view usage] : c.44.1.0 |Phosphotyrosine protein phosphatases I-like |Phosphotyrosine protein phosphatases I |automated matches |automated matches |Bacillus subtilis [TaxId: 1423]
 d1aa2a_ :    (MET35)  (MET109)   [view usage] : a.40.1.1 |CH domain-like |Calponin-homology domain, CH-domain |Calponin-homology domain, CH-domain |beta-spectrin |Human (Homo sapiens) [TaxId: 9606]
 d1af0a2 :   (TYR169)  (TYR246)   [view usage] : d.92.1.6 |Zincin-like |Metalloproteases ("zincins"), catalytic domain |Serralysin-like metalloprotease, catalytic (N-terminal) domain |Metalloprotease |Serratia marcescens [TaxId: 615]
 d1itla_ :    (ALA70)  (LYS126)   [view usage] : a.26.1.2 |4-helical cytokines |4-helical cytokines |Short-chain cytokines |Interleukin-4 (IL-4) |Human (Homo sapiens) [TaxId: 9606]
 d1jxea1 :   (PRO373)  (LEU420)   [view usage] : c.55.3.5 |Ribonuclease H-like motif |Ribonuclease H-like |DnaQ-like 3'-5' exonuclease |Exonuclease domain of prokaryotic DNA polymerase |Thermus aquaticus [TaxId: 271]
 d2f96a1 :   (ALA164)  (GLY217)   [view usage] : c.55.3.5 |Ribonuclease H-like motif |Ribonuclease H-like |DnaQ-like 3'-5' exonuclease |Ribonuclease T |Pseudomonas aeruginosa [TaxId: 287]
 d1bala_ :    (SER13)   (HIS47)   [view usage] : a.9.1.1 |Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex |Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex |Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex |E3-binding domain of dihydrolipoamide succinyltransferase |Escherichia coli [TaxId: 562]
 d1pzra_ :    (ASP63)  (ARG117)   [view usage] : a.38.2.1 |HLH-like |Docking domain B of the erythromycin polyketide synthase (DEBS) |Docking domain B of the erythromycin polyketide synthase (DEBS) |Erythronolide synthase |Saccharopolyspora erythraea [TaxId: 1836]
 d1j53a_ :   (LEU131)  (GLY180)   [view usage] : c.55.3.5 |Ribonuclease H-like motif |Ribonuclease H-like |DnaQ-like 3'-5' exonuclease |N-terminal exonuclease domain of the epsilon subunit of DNA polymerase III |Escherichia coli [TaxId: 562]
 d2idoc_ :   (LEU131)  (GLY180)   [view usage] : c.55.3.5 |Ribonuclease H-like motif |Ribonuclease H-like |DnaQ-like 3'-5' exonuclease |automated matches |Escherichia coli [TaxId: 562]
 d4kk3a_ :   (THR104)  (ASP148)   [view usage] : c.44.1.0 |Phosphotyrosine protein phosphatases I-like |Phosphotyrosine protein phosphatases I |automated matches |automated matches |Bacillus subtilis [TaxId: 224308]
 d3wfla_ :   (ASP208)  (VAL265)   [view usage] : c.1.8.0 |TIM beta/alpha-barrel |(Trans)glycosidases |automated matches |automated matches |Talaromyces trachyspermus [TaxId: 28566]
 d1lbua1 :    (GLU17)   (GLN77)   [view usage] : a.20.1.1 |PGBD-like |PGBD-like |Peptidoglycan binding domain, PGBD |Zn2+ DD-carboxypeptidase, N-terminal domain |Streptomyces albus G [TaxId: 1962]
 d2y21j_ :   (HIS276)  (VAL328)   [view usage] : a.274.1.1 |HAMP domain-like |HAMP domain-like |HAMP domain |automated matches |Archaeoglobus fulgidus [TaxId: 2234]
 d2g9xb1 :   (GLY171)  (LYS194)   [view usage] : a.74.1.1 |Cyclin-like |Cyclin-like |Cyclin |Cyclin A |Cow (Bos taurus) [TaxId: 9913]
 d1ck7a6 :    (THR45)   (LYS99)   [view usage] : a.20.1.2 |PGBD-like |PGBD-like |MMP N-terminal domain |Gelatinase A (MMP-2) |Human (Homo sapiens) [TaxId: 9606]
 d1vs6q1 :     (GLY6)   (GLY72)   [view usage] : a.144.2.1 |PABP domain-like |Ribosomal protein L20 |Ribosomal protein L20 |Ribosomal protein L20 |Escherichia coli [TaxId: 562]
 d3ngya_ :   (ALA152)  (GLY205)   [view usage] : c.55.3.5 |Ribonuclease H-like motif |Ribonuclease H-like |DnaQ-like 3'-5' exonuclease |automated matches |Escherichia coli [TaxId: 562]
 d2fv5b_ :   (LEU395)  (SER464)   [view usage] : d.92.1.10 |Zincin-like |Metalloproteases ("zincins"), catalytic domain |TNF-alpha converting enzyme, TACE, catalytic domain |TNF-alpha converting enzyme, TACE, catalytic domain |Human (Homo sapiens) [TaxId: 9606]
 d4akza_ :   (PRO135)  (TYR155)   [view usage] : d.17.4.26 |Cystatin-like |NTF2-like |VirB8-like |Type IV secretion system protein VirB8 |Brucella melitensis [TaxId: 29459]
 d3l2fb1 :    (THR63)  (HIS110)   [view usage] : a.83.1.0 |Guanido kinase N-terminal domain |Guanido kinase N-terminal domain |automated matches |automated matches |Namalycastis sp. [TaxId: 243920]
 d1eaka1 :    (THR45)   (LYS99)   [view usage] : a.20.1.2 |PGBD-like |PGBD-like |MMP N-terminal domain |Gelatinase A (MMP-2) |Human (Homo sapiens) [TaxId: 9606]
 d4trib_ :    (PRO84)  (GLY124)   [view usage] : a.104.1.0 |Cytochrome P450 |Cytochrome P450 |automated matches |automated matches |Mycobacterium smegmatis [TaxId: 246196]
 d1bgxt3 :   (PRO373)  (LEU420)   [view usage] : c.55.3.5 |Ribonuclease H-like motif |Ribonuclease H-like |DnaQ-like 3'-5' exonuclease |Exonuclease domain of prokaryotic DNA polymerase |Thermus aquaticus [TaxId: 271]
 d1xtnb_ :    (TYR45)   (TYR98)   [view usage] : d.189.1.1 |PX domain |PX domain |PX domain |Serine/threonine-protein kinase Sgk3, Cisk |Mouse (Mus musculus) [TaxId: 10090]
 d3l2eb1 :    (THR63)  (HIS110)   [view usage] : a.83.1.0 |Guanido kinase N-terminal domain |Guanido kinase N-terminal domain |automated matches |automated matches |Namalycastis sp. [TaxId: 243920]
 d2oqmb_ :    (VAL63)  (ALA108)   [view usage] : a.213.1.3 |DinB/YfiT-like putative metalloenzymes |DinB/YfiT-like putative metalloenzymes |Sden0562-like |Hypothetical protein Sden0562 |Shewanella denitrificans [TaxId: 192073]
 d3ihoa_ :   (GLY538)  (ASN573)   [view usage] : a.96.1.2 |DNA-glycosylase |DNA-glycosylase |Mismatch glycosylase |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d2guia_ :   (LEU131)  (GLY180)   [view usage] : c.55.3.5 |Ribonuclease H-like motif |Ribonuclease H-like |DnaQ-like 3'-5' exonuclease |automated matches |Escherichia coli [TaxId: 562]
 d2e7ua_ :   (GLU239)  (GLY256)   [view usage] : c.67.1.0 |PLP-dependent transferase-like |PLP-dependent transferases |automated matches |automated matches |Thermus thermophilus HB8 [TaxId: 300852]
 d1j5sa_ :    (PRO96)  (THR135)   [view usage] : c.1.9.8 |TIM beta/alpha-barrel |Metallo-dependent hydrolases |Uronate isomerase-like |Uronate isomerase TM0064 |Thermotoga maritima [TaxId: 2336]
 d4nhff_ :   (ALA130)  (VAL149)   [view usage] : d.17.4.0 |Cystatin-like |NTF2-like |automated matches |automated matches |Bartonella grahamii [TaxId: 634504]

List of distinct SCOP folds where this concept is used (in one or more of its domains):
   c.1,    c.67,   a.104,   a.128,    d.92,    c.77,    c.55,    a.96,    d.17,    a.74,    a.83,    a.40,    a.26,    c.44,    a.28,    a.38,   a.144,     b.8,   d.189,   a.213,  
a.20, a.9, a.274