Protein Concepts Dictionary

Tableau information

Concept source:  d2ie3a_  amino acid (a.a.) range (LEU29)(SER49)

nSSEs in this Concept: 3

String of secondary struct.elems. (SSEs) defining this concept: HHH

Each SSE's a.a.range: (start resi) (end resi) SSEtype (H=Helix; E=Strand) followed by a numeric SSE ID:
	   (LEU29)   (LEU35) H1
	   (LEU35)   (ALA41) H2
	   (GLY43)   (SER49) H3

Orientation angles° of SSE-pairs; those in contact shown in bold font
          H1                   
H2      -61.0°   H2            
H3     -129.9°  114.8°       
Footnote: Inferred from this concept's usages (listed below) was the angular variance of 1σ = ±12.4°  about each orientation angle shown above.

Loci of concept usages (shown as a range of a.a. residue ids) in SCOP(v2.05) domains, along with their brief legend taken from SCOP
 d1o7fa1 :   (LEU294)  (ARG321)   [view usage] : a.4.5.31 |DNA/RNA-binding 3-helical bundle |"Winged helix" DNA-binding domain |DEP domain |Regulatory domain of epac2, domain 2 |Mouse (Mus musculus) [TaxId: 10090]
 d1mx3a1 :   (GLU126)  (SER167)   [view usage] : c.2.1.4 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |Formate/glycerate dehydrogenases, NAD-domain |Transcription corepressor CtbP |Human (Homo sapiens), Ctbp1 [TaxId: 9606]
 d1htoa2 :   (SER291)  (VAL323)   [view usage] : d.128.1.1 |Glutamine synthetase/guanido kinase |Glutamine synthetase/guanido kinase |Glutamine synthetase catalytic domain |Glutamine synthetase, C-terminal domain |Mycobacterium tuberculosis [TaxId: 1773]
 d3zsna_ :   (ASP328)  (LEU367)   [view usage] : a.104.1.0 |Cytochrome P450 |Cytochrome P450 |automated matches |automated matches |Micromonospora griseorubida [TaxId: 28040]
 d1w07a2 :   (LYS473)  (LEU515)   [view usage] : a.29.3.2 |Bromodomain-like |Acyl-CoA dehydrogenase C-terminal domain-like |acyl-CoA oxidase C-terminal domains |Acyl-coenzyme A oxidase 1, domains 3 and 4 |Thale cress (Arabidopsis thaliana) [TaxId: 3702]
 d3fe1a1 :   (ASP154)  (ARG190)   [view usage] : c.55.1.0 |Ribonuclease H-like motif |Actin-like ATPase domain |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d3uk0a_ :   (THR245)  (VAL264)   [view usage] : c.93.1.0 |Periplasmic binding protein-like I |Periplasmic binding protein-like I |automated matches |automated matches |Rhodopseudomonas palustris [TaxId: 316057]
 d4pxhc_ :   (ASP339)  (TYR377)   [view usage] : a.104.1.0 |Cytochrome P450 |Cytochrome P450 |automated matches |automated matches |Streptomyces sp. [TaxId: 1001349]
 d1p8za2 :   (PHE352)  (VAL370)   [view usage] : c.55.1.1 |Ribonuclease H-like motif |Actin-like ATPase domain |Actin/HSP70 |Actin |Rabbit (Oryctolagus cuniculus) [TaxId: 9986]
 d3hbfa_ :   (PRO149)  (ASP172)   [view usage] : c.87.1.0 |UDP-Glycosyltransferase/glycogen phosphorylase |UDP-Glycosyltransferase/glycogen phosphorylase |automated matches |automated matches |Medicago truncatula [TaxId: 3880]
 d2y5na_ :   (ASP328)  (LEU367)   [view usage] : a.104.1.0 |Cytochrome P450 |Cytochrome P450 |automated matches |automated matches |Micromonospora griseorubida [TaxId: 28040]
 d4e3ta_ :   (PHE313)  (SER359)   [view usage] : c.1.9.3 |TIM beta/alpha-barrel |Metallo-dependent hydrolases |Phosphotriesterase-like |automated matches |Brevundimonas diminuta [TaxId: 293]
 d1u7xa_ :   (SER106)  (ALA138)   [view usage] : c.26.1.1 |Adenine nucleotide alpha hydrolase-like |Nucleotidylyl transferase |Class I aminoacyl-tRNA synthetases (RS), catalytic domain |Tyrosyl-tRNA synthetase (TyrRS) |Methanococcus jannaschii [TaxId: 2190]
 d3rysa_ :    (HIS21)   (LYS53)   [view usage] : c.1.9.0 |TIM beta/alpha-barrel |Metallo-dependent hydrolases |automated matches |automated matches |Arthrobacter aurescens [TaxId: 290340]
 d1b8pa2 :   (ARG219)  (GLY259)   [view usage] : d.162.1.1 |LDH C-terminal domain-like |LDH C-terminal domain-like |Lactate & malate dehydrogenases, C-terminal domain |Malate dehydrogenase |Aquaspirillum arcticum [TaxId: 87645]
 d2gkpa1 :    (SER69)  (PHE105)   [view usage] : d.351.1.1 |NMB0488-like |NMB0488-like |NMB0488-like |Hypothetical protein NMB0488 |Neisseria meningitidis [TaxId: 487]
 d3zowp_ :    (CYS10)   (THR40)   [view usage] : a.3.1.1 |Cytochrome c |Cytochrome c |monodomain cytochrome c |Cytochrome c552 |Nitrosomonas europaea [TaxId: 915]
 d1sk8a_ :   (ASP339)  (ASP370)   [view usage] : c.60.1.2 |Phosphoglycerate mutase-like |Phosphoglycerate mutase-like |Histidine acid phosphatase |Phytase (myo-inositol-hexakisphosphate-3-phosphohydrolase) |Aspergillus fumigatus [TaxId: 5085]
 d3sbpg1 :   (GLY106)  (PHE123)   [view usage] : b.69.3.1 |7-bladed beta-propeller |Nitrous oxide reductase, N-terminal domain |Nitrous oxide reductase, N-terminal domain |automated matches |Pseudomonas stutzeri [TaxId: 316]
 d3sbpa1 :   (GLY106)  (PHE123)   [view usage] : b.69.3.1 |7-bladed beta-propeller |Nitrous oxide reductase, N-terminal domain |Nitrous oxide reductase, N-terminal domain |automated matches |Pseudomonas stutzeri [TaxId: 316]
 d2e74b1 :   (ASN122)  (LEU157)   [view usage] : f.32.1.1 |a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) |a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) |a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) |Subunit IV of the cytochrome b6f complex |Mastigocladus laminosus [TaxId: 83541]
 d2nyla1 :   (TRP257)  (THR281)   [view usage] : a.118.1.2 |alpha-alpha superhelix |ARM repeat |HEAT repeat |Constant regulatory domain of protein phosphatase 2a, pr65alpha |Human (Homo sapiens) [TaxId: 9606]
 d2fonb3 :   (GLN473)  (GLU514)   [view usage] : a.29.3.0 |Bromodomain-like |Acyl-CoA dehydrogenase C-terminal domain-like |automated matches |automated matches |Solanum lycopersicum [TaxId: 4081]
 d2vsga_ :   (THR262)  (LYS296)   [view usage] : h.4.1.1 |Antiparallel coiled-coil |Variant surface glycoprotein (N-terminal domain) |Variant surface glycoprotein (N-terminal domain) |Variant surface glycoprotein (N-terminal domain) |Trypanosome (Trypanosoma brucei) [TaxId: 5691]
 d4updb_ :   (PHE464)  (ALA502)   [view usage] : c.69.1.0 |alpha/beta-Hydrolases |alpha/beta-Hydrolases |automated matches |automated matches |Ophiostoma piceae [TaxId: 61273]
 d1by1a_ :    (SER51)   (LEU95)   [view usage] : a.87.1.1 |DBL homology domain (DH-domain) |DBL homology domain (DH-domain) |DBL homology domain (DH-domain) |beta-pix |Human (Homo sapiens) [TaxId: 9606]
 d4axhb1 :   (THR392)  (ARG414)   [view usage] : d.157.1.0 |Metallo-hydrolase/oxidoreductase |Metallo-hydrolase/oxidoreductase |automated matches |automated matches |Pseudomonas sp. [TaxId: 1007495]
 d3cqxa1 :   (ASN151)  (LYS188)   [view usage] : c.55.1.1 |Ribonuclease H-like motif |Actin-like ATPase domain |Actin/HSP70 |automated matches |Mouse (Mus musculus) [TaxId: 10090]
 d1ar1a_ :   (THR213)  (GLY261)   [view usage] : f.24.1.1 |Cytochrome c oxidase subunit I-like |Cytochrome c oxidase subunit I-like |Cytochrome c oxidase subunit I-like |Bacterial aa3 type cytochrome c oxidase subunit I |Paracoccus denitrificans [TaxId: 266]
 d3vpqa2 :   (ASP171)  (ALA199)   [view usage] : a.45.1.0 |GST C-terminal domain-like |GST C-terminal domain-like |automated matches |automated matches |Silkworm (Bombyx mori) [TaxId: 7091]
 d3nvia_ :   (ARG131)  (PRO172)   [view usage] : a.183.1.0 |Nop domain |Nop domain |automated matches |automated matches |Pyrococcus furiosus [TaxId: 186497]
 d3r9sa_ :   (ALA185)  (GLY216)   [view usage] : c.14.1.0 |ClpP/crotonase |ClpP/crotonase |automated matches |automated matches |Mycobacterium avium [TaxId: 243243]
 d2y5nb_ :   (ASP328)  (LEU367)   [view usage] : a.104.1.0 |Cytochrome P450 |Cytochrome P450 |automated matches |automated matches |Micromonospora griseorubida [TaxId: 28040]
 d2qypa_ :     (ASP2)   (THR53)   [view usage] : a.64.1.1 |Saposin-like |Saposin |NKL-like |Saposin C |Human (Homo sapiens) [TaxId: 9606]
 d1n83a_ :   (LEU304)  (PHE372)   [view usage] : a.123.1.1 |Nuclear receptor ligand-binding domain |Nuclear receptor ligand-binding domain |Nuclear receptor ligand-binding domain |Orphan nuclear receptor ROR-alpha |Human (Homo sapiens) [TaxId: 9606]
 d3zkka_ :   (GLN328)  (ALA378)   [view usage] : c.94.1.0 |Periplasmic binding protein-like II |Periplasmic binding protein-like II |automated matches |automated matches |Bifidobacterium animalis [TaxId: 580050]
 d2i6ea1 :   (ALA217)  (ASN258)   [view usage] : c.94.1.1 |Periplasmic binding protein-like II |Periplasmic binding protein-like II |Phosphate binding protein-like |Hypothetical protein DR0370 |Deinococcus radiodurans [TaxId: 1299]
 d1iz9a2 :   (PHE218)  (ILE249)   [view usage] : d.162.1.1 |LDH C-terminal domain-like |LDH C-terminal domain-like |Lactate & malate dehydrogenases, C-terminal domain |Malate dehydrogenase |Thermus thermophilus [TaxId: 274]
 d4olqc_ :    (ASP66)   (SER97)   [view usage] : c.14.1.0 |ClpP/crotonase |ClpP/crotonase |automated matches |automated matches |Hyphomonas neptunium [TaxId: 228405]
 d3d2eb1 :   (ASN151)  (THR188)   [view usage] : c.55.1.1 |Ribonuclease H-like motif |Actin-like ATPase domain |Actin/HSP70 |Heat shock protein 70kDa, ATPase fragment |Human (Homo sapiens) [TaxId: 9606]
 d1uhna_ :   (HIS115)  (GLY156)   [view usage] : a.39.1.5 |EF Hand-like |EF-hand |Calmodulin-like |Calcineurin B-like protein 2 |Thale cress (Arabidopsis thaliana) [TaxId: 3702]
 d3dvua_ :     (SER6)   (LYS65)   [view usage] : f.1.4.1 |Toxins' membrane translocation domains |Bcl-2 inhibitors of programmed cell death |Bcl-2 inhibitors of programmed cell death |Bcl-2 homolog V-bcl-2 |Murid herpesvirus 4 [TaxId: 33708]
 d4aw3a_ :   (ASP328)  (ARG366)   [view usage] : a.104.1.0 |Cytochrome P450 |Cytochrome P450 |automated matches |automated matches |Micromonospora griseorubida [TaxId: 28040]
 d3o8yb2 :   (SER171)  (ILE214)   [view usage] : a.119.1.0 |Lipoxigenase |Lipoxigenase |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d4bgva1 :   (THR125)  (ILE147)   [view usage] : c.2.1.0 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |automated matches |automated matches |Picrophilus torridus [TaxId: 82076]
 d1y37a_ :   (PRO158)  (ASP185)   [view usage] : c.69.1.0 |alpha/beta-Hydrolases |alpha/beta-Hydrolases |automated matches |automated matches |Burkholderia sp. [TaxId: 384033]
 d1bc9a_ :   (LYS160)  (GLN181)   [view usage] : a.118.3.1 |alpha-alpha superhelix |Sec7 domain |Sec7 domain |Cytohesin-1/b2-1 |Human (Homo sapiens) [TaxId: 9606]
 d1ii2a1 :   (PRO469)  (ALA515)   [view usage] : c.91.1.1 |PEP carboxykinase-like |PEP carboxykinase-like |PEP carboxykinase C-terminal domain |Phosphoenolpyruvate (PEP) carboxykinase (ATP-oxaloacetate carboxy-lyase) |Trypanosoma cruzi [TaxId: 5693]
 d4jeia_ :   (ASN270)  (GLN291)   [view usage] : c.69.1.0 |alpha/beta-Hydrolases |alpha/beta-Hydrolases |automated matches |automated matches |Yarrowia lipolytica [TaxId: 4952]
 d1xtnb_ :    (TYR98)  (GLN119)   [view usage] : d.189.1.1 |PX domain |PX domain |PX domain |Serine/threonine-protein kinase Sgk3, Cisk |Mouse (Mus musculus) [TaxId: 10090]
 d3o8aa_ :   (GLY350)  (PHE417)   [view usage] : c.1.4.1 |TIM beta/alpha-barrel |FMN-linked oxidoreductases |FMN-linked oxidoreductases |automated matches |Plasmodium falciparum [TaxId: 36329]
 d3sbpd1 :   (GLY106)  (PHE123)   [view usage] : b.69.3.1 |7-bladed beta-propeller |Nitrous oxide reductase, N-terminal domain |Nitrous oxide reductase, N-terminal domain |automated matches |Pseudomonas stutzeri [TaxId: 316]
 d4g6ub_ :    (LEU68)  (PHE104)   [view usage] : d.351.1.0 |NMB0488-like |NMB0488-like |automated matches |automated matches |Escherichia coli [TaxId: 83334]
 d1f1ha2 :   (GLU292)  (VAL323)   [view usage] : d.128.1.1 |Glutamine synthetase/guanido kinase |Glutamine synthetase/guanido kinase |Glutamine synthetase catalytic domain |Glutamine synthetase, C-terminal domain |Salmonella typhimurium [TaxId: 90371]
 d3hbja_ :   (GLY148)  (ASP172)   [view usage] : c.87.1.0 |UDP-Glycosyltransferase/glycogen phosphorylase |UDP-Glycosyltransferase/glycogen phosphorylase |automated matches |automated matches |Medicago truncatula [TaxId: 3880]

List of distinct SCOP folds where this concept is used (in one or more of its domains):
   c.1,   a.119,    c.69,    c.94,   a.104,     c.2,    b.69,   a.118,    c.26,   d.157,    c.93,    c.14,    c.55,    c.87,    c.60,   a.123,    f.24,     a.4,    a.39,   d.162,  
d.128, c.91, a.45, a.3, a.29, f.1, a.87, h.4, a.64, d.189, a.183, f.32, d.351