Protein Concepts Dictionary

Tableau information

Concept source:  d1y2ac_  amino acid (a.a.) range (LEU246)(THR279)

nSSEs in this Concept: 3

String of secondary struct.elems. (SSEs) defining this concept: HHH

Each SSE's a.a.range: (start resi) (end resi) SSEtype (H=Helix; E=Strand) followed by a numeric SSE ID:
	  (LEU246)  (ILE252) H1
	  (LEU253)  (HIS262) H2
	  (ASP264)  (THR279) H3

Orientation angles° of SSE-pairs; those in contact shown in bold font
          H1                   
H2       43.2°   H2            
H3     -150.8° -138.4°       
Footnote: Inferred from this concept's usages (listed below) was the angular variance of 1σ = ±9.4°  about each orientation angle shown above.

Loci of concept usages (shown as a range of a.a. residue ids) in SCOP(v2.05) domains, along with their brief legend taken from SCOP
 d1alaa_ :   (GLN220)  (SER246)   [view usage] : a.65.1.1 |Annexin |Annexin |Annexin |Annexin V |Chicken (Gallus gallus) [TaxId: 9031]
 d3gw9a_ :   (ASP193)  (ASN253)   [view usage] : a.104.1.0 |Cytochrome P450 |Cytochrome P450 |automated matches |automated matches |Trypanosome (Trypanosoma brucei) [TaxId: 5691]
 d1ujwb_ :   (TYR323)  (GLU436)   [view usage] : h.4.9.1 |Antiparallel coiled-coil |Colicin E3 receptor domain |Colicin E3 receptor domain |Colicin E3 receptor domain |Escherichia coli [TaxId: 562]
 d1wu3i_ :     (LYS4)   (GLU99)   [view usage] : a.26.1.3 |4-helical cytokines |4-helical cytokines |Interferons/interleukin-10 (IL-10) |Interferon-beta |Mouse (Mus musculus) [TaxId: 10090]
 d2ysub1 :   (GLU324)  (LYS438)   [view usage] : h.4.9.1 |Antiparallel coiled-coil |Colicin E3 receptor domain |Colicin E3 receptor domain |Colicin E3 receptor domain |Escherichia coli [TaxId: 562]
 d4dvhb1 :    (SER21)   (ILE86)   [view usage] : a.2.11.0 |Long alpha-hairpin |Fe,Mn superoxide dismutase (SOD), N-terminal domain |automated matches |automated matches |Trypanosoma cruzi [TaxId: 353153]
 d1lwua_ :    (ASN95)  (ALA182)   [view usage] : h.1.8.1 |Parallel coiled-coil |Fibrinogen coiled-coil and central regions |Fibrinogen coiled-coil and central regions |Fibrinogen alpha chain |Sea lamprey (Petromyzon marinus) [TaxId: 7757]
 d1xsva_ :    (GLU74)  (GLU110)   [view usage] : a.4.13.3 |DNA/RNA-binding 3-helical bundle |Sigma3 and sigma4 domains of RNA polymerase sigma factors |YlxM/p13-like |Hypothetical protein SAV1236 |Staphylococcus aureus, strain Mu50 / ATCC 700699 [TaxId: 1280]
 d4f2na1 :    (SER51)  (LEU115)   [view usage] : a.2.11.0 |Long alpha-hairpin |Fe,Mn superoxide dismutase (SOD), N-terminal domain |automated matches |automated matches |Leishmania major [TaxId: 5664]
 d4m32a_ :   (SER103)  (ILE154)   [view usage] : a.25.1.0 |Ferritin-like |Ferritin-like |automated matches |automated matches |Mycobacterium smegmatis [TaxId: 246196]
 d2klya_ :   (SER115)  (GLY164)   [view usage] : d.20.1.1 |UBC-like |UBC-like |UBC-related |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d4phqa_ :     (ASP7)  (TYR104)   [view usage] : h.4.4.1 |Antiparallel coiled-coil |Bacterial hemolysins |Hemolysin E (HlyE, ClyA, SheA) |automated matches |Escherichia coli [TaxId: 83333]
 d1u7ma1 :     (TYR3)   (ASN52)   [view usage] : k.8.1.1 |Designed four-helix bundle protein |Designed four-helix bundle protein |Designed four-helix bundle protein |Artificial diiron protein |Synthetic, different variants
 d2z55a_ :    (ARG11)   (GLY67)   [view usage] : f.13.1.1 |Family A G protein-coupled receptor-like |Family A G protein-coupled receptor-like |Bacteriorhodopsin-like |automated matches |Halobacterium sp. [TaxId: 29285]
 d2nn4a1 :     (THR3)   (THR62)   [view usage] : a.272.1.1 |YqgQ-like |YqgQ-like |YqgQ-like |Hypothetical protein YqgQ |Bacillus subtilis [TaxId: 1423]
 d1v8ga2 :   (HIS154)  (THR180)   [view usage] : c.27.1.1 |Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain |Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain |Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain |Anthranilate phosphoribosyltransferase (TrpD) |Thermus thermophilus [TaxId: 274]
 d4kysb_ :   (SER354)  (ASN375)   [view usage] : c.94.1.0 |Periplasmic binding protein-like II |Periplasmic binding protein-like II |automated matches |automated matches |Clostridium botulinum [TaxId: 441770]
 d1zdna1 :   (ILE109)  (GLY156)   [view usage] : d.20.1.1 |UBC-like |UBC-like |UBC-related |Ubiquitin conjugating enzyme, UBC |Human (Homo sapiens), E2 S [TaxId: 9606]
 d1h8ee1 :   (GLU366)  (LEU414)   [view usage] : a.69.1.1 |Left-handed superhelix |C-terminal domain of alpha and beta subunits of F1 ATP synthase |C-terminal domain of alpha and beta subunits of F1 ATP synthase |F1 ATP synthase beta subunit, domain 3 |Cow (Bos taurus) [TaxId: 9913]
 d1s05a_ :     (ASP3)   (PHE55)   [view usage] : a.24.3.2 |Four-helical up-and-down bundle |Cytochromes |Cytochrome c'-like |Cytochrome c-556 |Rhodopseudomonas palustris [TaxId: 1076]
 d4j7kb_ :     (PRO8)   (TYR65)   [view usage] : a.25.3.0 |Ferritin-like |EsxAB dimer-like |automated matches |automated matches |Bacillus anthracis [TaxId: 260799]
 d1ng9a1 :   (THR335)  (ASP386)   [view usage] : a.113.1.1 |DNA repair protein MutS, domain III |DNA repair protein MutS, domain III |DNA repair protein MutS, domain III |DNA repair protein MutS, domain III |Escherichia coli [TaxId: 562]
 d1fyzc_ :   (ASN137)  (ILE193)   [view usage] : a.25.1.2 |Ferritin-like |Ferritin-like |Ribonucleotide reductase-like |Methane monooxygenase hydrolase beta subunit |Methylococcus capsulatus [TaxId: 414]
 d2ij5a_ :   (PRO153)  (ASN195)   [view usage] : a.104.1.1 |Cytochrome P450 |Cytochrome P450 |Cytochrome P450 |Cyp121 monooxygenase (P450 Mt2) |Mycobacterium tuberculosis [TaxId: 1773]
 d4phoa_ :     (ASP7)  (PHE101)   [view usage] : h.4.4.1 |Antiparallel coiled-coil |Bacterial hemolysins |Hemolysin E (HlyE, ClyA, SheA) |automated matches |Escherichia coli [TaxId: 83333]
 d1ft1a_ :    (ARG69)  (LEU119)   [view usage] : a.118.6.1 |alpha-alpha superhelix |Protein prenylyltransferase |Protein prenylyltransferase |Protein farnesyltransferase alpha-subunit |Norway rat (Rattus norvegicus) [TaxId: 10116]
 d1wp1a_ :   (SER339)  (GLY447)   [view usage] : f.5.1.1 |Outer membrane efflux proteins (OEP) |Outer membrane efflux proteins (OEP) |Outer membrane efflux proteins (OEP) |Outer membrane protein OprM |Pseudomonas aeruginosa [TaxId: 287]
 d4az9b_ :    (TYR39)  (ASN101)   [view usage] : d.189.1.0 |PX domain |PX domain |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1h16a_ :   (ILE189)  (LYS239)   [view usage] : c.7.1.1 |PFL-like glycyl radical enzymes |PFL-like glycyl radical enzymes |PFL-like |Pyruvate formate-lyase, PFL |Escherichia coli [TaxId: 562]
 d4az9a_ :    (SER40)  (ASN101)   [view usage] : d.189.1.0 |PX domain |PX domain |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1wdza1 :     (ARG5)  (LEU102)   [view usage] : a.238.1.3 |BAR/IMD domain-like |BAR/IMD domain-like |IMD domain |BAP2/IRSp53 N-terminal domain |Human (Homo sapiens) [TaxId: 9606]
 d1e6yb1 :  (ALA2321) (HIS2362)   [view usage] : a.89.1.1 |Methyl-coenzyme M reductase alpha and beta chain C-terminal domain |Methyl-coenzyme M reductase alpha and beta chain C-terminal domain |Methyl-coenzyme M reductase alpha and beta chain C-terminal domain |Beta chain |Methanosarcina barkeri [TaxId: 2208]
 d1sjja_ :   (LEU665)  (THR738)   [view usage] : i.15.1.1 |Muscle protein complexes |Muscle protein complexes |Muscle protein complexes |Actinin |Chicken (Gallus gallus) [TaxId: 9031]
 d1oaoc_ :    (LEU62)  (TYR118)   [view usage] : e.26.1.3 |Prismane protein-like |Prismane protein-like |Acetyl-CoA synthase |Bifunctional carbon monoxide dehydrogenase/acetyl-CoA synthase (CODH/ACS) alpha (ACS) subunit |Moorella thermoacetica [TaxId: 1525]
 d1fzic_ :   (ASN137)  (ILE193)   [view usage] : a.25.1.2 |Ferritin-like |Ferritin-like |Ribonucleotide reductase-like |Methane monooxygenase hydrolase beta subunit |Methylococcus capsulatus [TaxId: 414]
 d3ongd_ :   (THR108)  (TYR155)   [view usage] : d.20.1.1 |UBC-like |UBC-like |UBC-related |automated matches |Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]
 d2ekea_ :   (THR108)  (TYR155)   [view usage] : d.20.1.1 |UBC-like |UBC-like |UBC-related |Ubiquitin conjugating enzyme, UBC |Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]
 d1jcha3 :   (ALA318)  (LYS450)   [view usage] : h.4.9.1 |Antiparallel coiled-coil |Colicin E3 receptor domain |Colicin E3 receptor domain |Colicin E3 receptor domain |Escherichia coli [TaxId: 562]
 d3gw9b_ :   (ARG195)  (ASN253)   [view usage] : a.104.1.0 |Cytochrome P450 |Cytochrome P450 |automated matches |automated matches |Trypanosome (Trypanosoma brucei) [TaxId: 5691]
 d1r8lb_ :   (LEU333)  (PHE364)   [view usage] : c.1.8.3 |TIM beta/alpha-barrel |(Trans)glycosidases |beta-glycanases |Beta-1,4-galactanase |Bacillus licheniformis [TaxId: 1402]
 d3llrd_ :    (PHE76)  (GLY107)   [view usage] : b.34.9.0 |SH3-like barrel |Tudor/PWWP/MBT |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1t0rb_ :   (THR114)  (CYS179)   [view usage] : a.25.1.2 |Ferritin-like |Ferritin-like |Ribonucleotide reductase-like |Toluene, o-xylene monooxygenase oxygenase subunit TouE |Pseudomonas stutzeri [TaxId: 316]
 d4phqc_ :     (CYS6)  (LEU100)   [view usage] : h.4.4.1 |Antiparallel coiled-coil |Bacterial hemolysins |Hemolysin E (HlyE, ClyA, SheA) |automated matches |Escherichia coli [TaxId: 83333]
 d2yb6a_ :   (VAL102)  (SER148)   [view usage] : d.20.1.1 |UBC-like |UBC-like |UBC-related |Ubiquitin conjugating enzyme, UBC |Human (Homo sapiens), ubc2b [TaxId: 9606]
 d2g38c_ :    (LEU11)   (THR81)   [view usage] : a.25.4.1 |Ferritin-like |PE/PPE dimer-like |PE |PE25 |Mycobacterium tuberculosis [TaxId: 1773]
 d2ybfa_ :   (ASP101)  (SER148)   [view usage] : d.20.1.1 |UBC-like |UBC-like |UBC-related |Ubiquitin conjugating enzyme, UBC |Human (Homo sapiens), ubc2b [TaxId: 9606]
 d3d5ka_ :   (SER339)  (GLY447)   [view usage] : f.5.1.1 |Outer membrane efflux proteins (OEP) |Outer membrane efflux proteins (OEP) |Outer membrane efflux proteins (OEP) |Outer membrane protein OprM |Pseudomonas aeruginosa [TaxId: 287]
 d1pgja1 :   (GLN400)  (THR440)   [view usage] : a.100.1.1 |6-phosphogluconate dehydrogenase C-terminal domain-like |6-phosphogluconate dehydrogenase C-terminal domain-like |Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain |6-phosphogluconate dehydrogenase (6PGD) |Trypanosome (Trypanosoma brucei) [TaxId: 5691]
 d1n4pa_ :    (ARG69)  (THR120)   [view usage] : a.118.6.1 |alpha-alpha superhelix |Protein prenylyltransferase |Protein prenylyltransferase |Protein farnesyltransferase alpha-subunit |Norway rat (Rattus norvegicus) [TaxId: 10116]
 d2xlva_ :     (PRO5)   (GLY60)   [view usage] : a.24.3.2 |Four-helical up-and-down bundle |Cytochromes |Cytochrome c'-like |automated matches |Achromobacter xylosoxidans [TaxId: 85698]
 d3h8ka_ :   (SER115)  (GLY164)   [view usage] : d.20.1.1 |UBC-like |UBC-like |UBC-related |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d4pe3a_ :   (ASP113)  (ASN129)   [view usage] : c.94.1.0 |Periplasmic binding protein-like II |Periplasmic binding protein-like II |automated matches |automated matches |Rhodobacter sphaeroides [TaxId: 349101]
 d1il6a_ :    (THR21)  (LYS129)   [view usage] : a.26.1.1 |4-helical cytokines |4-helical cytokines |Long-chain cytokines |Interleukin-6 |Human (Homo sapiens) [TaxId: 9606]
 d1oaod_ :    (LEU62)  (TYR118)   [view usage] : e.26.1.3 |Prismane protein-like |Prismane protein-like |Acetyl-CoA synthase |Bifunctional carbon monoxide dehydrogenase/acetyl-CoA synthase (CODH/ACS) alpha (ACS) subunit |Moorella thermoacetica [TaxId: 1525]
 d2ccya_ :     (PRO5)   (LEU53)   [view usage] : a.24.3.2 |Four-helical up-and-down bundle |Cytochromes |Cytochrome c'-like |Cytochrome c' |Rhodospirillum molischianum [TaxId: 1083]
 d1zj8a3 :   (LEU521)  (ARG555)   [view usage] : d.134.1.1 |Nitrite and sulphite reductase 4Fe-4S domain-like |Nitrite and sulphite reductase 4Fe-4S domain-like |Nitrite and sulphite reductase 4Fe-4S domain-like |Sulfite reductase NirA |Mycobacterium tuberculosis [TaxId: 1773]
 d4j11b_ :     (PRO8)   (TYR65)   [view usage] : a.25.3.0 |Ferritin-like |EsxAB dimer-like |automated matches |automated matches |Bacillus anthracis [TaxId: 260799]
 d3fe7a_ :    (LEU31)   (LEU85)   [view usage] : a.42.1.0 |SWIB/MDM2 domain |SWIB/MDM2 domain |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1dova_ :   (VAL201)  (ALA261)   [view usage] : a.24.9.1 |Four-helical up-and-down bundle |alpha-catenin/vinculin-like |alpha-catenin/vinculin |alpha-catenin |Mouse (Mus musculus) [TaxId: 10090]
 d1gqaa_ :     (ALA3)   (LYS51)   [view usage] : a.24.3.2 |Four-helical up-and-down bundle |Cytochromes |Cytochrome c'-like |Cytochrome c' |Rhodobacter sphaeroides [TaxId: 1063]
 d1ijya_ :    (SER82)  (ARG107)   [view usage] : a.141.1.1 |Frizzled cysteine-rich domain |Frizzled cysteine-rich domain |Frizzled cysteine-rich domain |Frizzled 8 (FZ8) |Mouse (Mus musculus) [TaxId: 10090]
 d4h3ea1 :    (SER52)  (ILE117)   [view usage] : a.2.11.0 |Long alpha-hairpin |Fe,Mn superoxide dismutase (SOD), N-terminal domain |automated matches |automated matches |Trypanosoma cruzi [TaxId: 353153]
 d2aaka_ :   (ASP101)  (TRP149)   [view usage] : d.20.1.1 |UBC-like |UBC-like |UBC-related |Ubiquitin conjugating enzyme, UBC |Thale cress (Arabidopsis thaliana) [TaxId: 3702]
 d1khca_ :   (PHE290)  (ALA320)   [view usage] : b.34.9.2 |SH3-like barrel |Tudor/PWWP/MBT |PWWP domain |DNA methyltransferase DNMT3B |Mouse (Mus musculus) [TaxId: 10090]
 d1avha_ :   (GLN220)  (SER246)   [view usage] : a.65.1.1 |Annexin |Annexin |Annexin |Annexin V |Human (Homo sapiens) [TaxId: 9606]
 d3p0ca_ :    (TYR50)  (HIS116)   [view usage] : d.189.1.0 |PX domain |PX domain |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d4w4ka_ :     (PRO8)   (THR89)   [view usage] : a.25.4.1 |Ferritin-like |PE/PPE dimer-like |PE |automated matches |Mycobacterium tuberculosis [TaxId: 652616]
 d2g38a1 :    (ALA10)   (ALA84)   [view usage] : a.25.4.1 |Ferritin-like |PE/PPE dimer-like |PE |PE25 |Mycobacterium tuberculosis [TaxId: 1773]
 d3flga_ :    (PHE79)  (GLY110)   [view usage] : b.34.9.2 |SH3-like barrel |Tudor/PWWP/MBT |PWWP domain |DNA methyltransferase DNMT3B |Human (Homo sapiens) [TaxId: 9606]
 d1e6ye1 :  (ALA5321) (HIS5362)   [view usage] : a.89.1.1 |Methyl-coenzyme M reductase alpha and beta chain C-terminal domain |Methyl-coenzyme M reductase alpha and beta chain C-terminal domain |Methyl-coenzyme M reductase alpha and beta chain C-terminal domain |Beta chain |Methanosarcina barkeri [TaxId: 2208]
 d1v9db_ :   (GLU883)  (GLY911)   [view usage] : a.207.1.1 |Formin homology 2 domain (FH2 domain) |Formin homology 2 domain (FH2 domain) |Formin homology 2 domain (FH2 domain) |Diaphanous protein homolog 1, dia1 |Mouse (Mus musculus) [TaxId: 10090]
 d2fwra1 :   (ALA272)  (ASN332)   [view usage] : c.37.1.19 |P-loop containing nucleoside triphosphate hydrolases |P-loop containing nucleoside triphosphate hydrolases |Tandem AAA-ATPase domain |DNA repair protein RAD25 |Archaeoglobus fulgidus [TaxId: 2234]
 d1fyzd_ :   (ASN137)  (ILE193)   [view usage] : a.25.1.2 |Ferritin-like |Ferritin-like |Ribonucleotide reductase-like |Methane monooxygenase hydrolase beta subunit |Methylococcus capsulatus [TaxId: 414]

List of distinct SCOP folds where this concept is used (in one or more of its domains):
   c.1,    c.94,   a.104,   a.118,    a.65,    c.37,     c.7,    i.15,    d.20,    a.25,   d.134,   a.100,    b.34,     a.4,    f.13,    e.26,    a.24,    a.42,    a.26,     h.4,  
c.27, a.113, a.69, a.2, k.8, a.89, d.189, a.238, h.1, a.207, a.141, f.5, a.272