Protein Concepts Dictionary

Tableau information

Concept source:  d1vr5a1  amino acid (a.a.) range (GLU113)(ASP137)

nSSEs in this Concept: 3

String of secondary struct.elems. (SSEs) defining this concept: HHE

Each SSE's a.a.range: (start resi) (end resi) SSEtype (H=Helix; E=Strand) followed by a numeric SSE ID:
	  (GLU113)  (TYR118) H1
	  (TYR123)  (TRP129) H2
	  (ARG132)  (ASP137) E3

Orientation angles° of SSE-pairs; those in contact shown in bold font
          H1                   
H2     -103.8°   H2            
E3     -151.2°   88.8°       
Footnote: Inferred from this concept's usages (listed below) was the angular variance of 1σ = ±7.3°  about each orientation angle shown above.

Loci of concept usages (shown as a range of a.a. residue ids) in SCOP(v2.05) domains, along with their brief legend taken from SCOP
 d4dnob_ :   (TYR136)  (GLN153)   [view usage] : c.69.1.0 |alpha/beta-Hydrolases |alpha/beta-Hydrolases |automated matches |automated matches |Pseudomonas aeruginosa [TaxId: 208963]
 d3kwka_ :   (ALA147)  (TYR178)   [view usage] : d.90.1.0 |FMN-dependent nitroreductase-like |FMN-dependent nitroreductase-like |automated matches |automated matches |Bacteroides thetaiotaomicron [TaxId: 226186]
 d3kd2a_ :   (TYR136)  (GLU153)   [view usage] : c.69.1.0 |alpha/beta-Hydrolases |alpha/beta-Hydrolases |automated matches |automated matches |Pseudomonas aeruginosa [TaxId: 208963]
 d4dc9d_ :   (GLY110)  (ASP149)   [view usage] : c.37.1.11 |P-loop containing nucleoside triphosphate hydrolases |P-loop containing nucleoside triphosphate hydrolases |RecA protein-like (ATPase-domain) |DNA repair protein Rad51, catalytic domain |Methanococcus voltae [TaxId: 2188]
 d1acfa_ :    (THR38)   (ALA63)   [view usage] : d.110.1.1 |Profilin-like |Profilin (actin-binding protein) |Profilin (actin-binding protein) |Profilin (actin-binding protein) |Acanthamoeba castellanii [TaxId: 5755]
 d1ru3a_ :   (HIS446)  (THR472)   [view usage] : e.26.1.3 |Prismane protein-like |Prismane protein-like |Acetyl-CoA synthase |Monomeric acetyl-CoA synthase |Carboxydothermus hydrogenoformans [TaxId: 129958]
 d1rkib_ :    (SER47)   (ASP71)   [view usage] : d.308.1.2 |THUMP domain |THUMP domain-like |PAE0736-like |Hypothetical protein PAE0736 |Pyrobaculum aerophilum [TaxId: 13773]
 d1ywha3 :   (ALA244)  (THR267)   [view usage] : g.7.1.3 |Snake toxin-like |Snake toxin-like |Extracellular domain of cell surface receptors |Urokinase plasminogen activator surface receptor uPAR |Human (Homo sapiens) [TaxId: 9606]
 d2y40b_ :   (TYR215)  (THR235)   [view usage] : c.77.1.1 |Isocitrate/Isopropylmalate dehydrogenase-like |Isocitrate/Isopropylmalate dehydrogenase-like |Dimeric isocitrate & isopropylmalate dehydrogenases |automated matches |Thermus thermophilus [TaxId: 274]
 d4dmhb_ :   (TYR136)  (GLU153)   [view usage] : c.69.1.0 |alpha/beta-Hydrolases |alpha/beta-Hydrolases |automated matches |automated matches |Pseudomonas aeruginosa [TaxId: 208963]
 d1xbna_ :     (THR4)   (LEU40)   [view usage] : d.278.1.1 |Ligand-binding domain in the NO signalling and Golgi transport |Ligand-binding domain in the NO signalling and Golgi transport |H-NOX domain |Methyl-accepting chemotaxis protein |Thermoanaerobacter tengcongensis [TaxId: 119072]
 d4nbra_ :   (THR207)  (PRO233)   [view usage] : c.2.1.0 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |automated matches |automated matches |Brucella abortus [TaxId: 262698]
 d2vk3a_ :    (THR43)   (GLY66)   [view usage] : d.110.1.1 |Profilin-like |Profilin (actin-binding protein) |Profilin (actin-binding protein) |automated matches |Norway rat (Rattus norvegicus) [TaxId: 10116]
 d3i99a1 :    (SER39)   (GLY61)   [view usage] : d.145.1.0 |FAD-binding/transporter-associated domain-like |FAD-binding/transporter-associated domain-like |automated matches |automated matches |Vibrio cholerae [TaxId: 243277]
 d1ajea_ :   (GLN116)  (ILE137)   [view usage] : c.37.1.8 |P-loop containing nucleoside triphosphate hydrolases |P-loop containing nucleoside triphosphate hydrolases |G proteins |CDC42 |Human (Homo sapiens) [TaxId: 9606]
 d2ahmf_ :   (GLN173)  (LEU194)   [view usage] : d.302.1.1 |Coronavirus NSP8-like |Coronavirus NSP8-like |Coronavirus NSP8-like |Nonstructural protein 8, NSP8 |SARS coronavirus [TaxId: 227859]
 d1fbub_ :   (PRO195)  (ASN227)   [view usage] : a.4.5.22 |DNA/RNA-binding 3-helical bundle |"Winged helix" DNA-binding domain |Heat-shock transcription factor |Heat-shock transcription factor |Milk yeast (Kluyveromyces lactis) [TaxId: 28985]
 d2huha1 :   (ASP190)  (VAL216)   [view usage] : b.7.5.1 |C2 domain-like |Smr-associated domain-like |Smr-associated domain |Putative DNA mismatch repair protein BT2179 |Bacteroides thetaiotaomicron [TaxId: 818]
 d4cbya_ :   (HIS678)  (LYS705)   [view usage] : c.42.1.2 |Arginase/deacetylase |Arginase/deacetylase |Histone deacetylase, HDAC |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1mpxa2 :   (ALA314)  (PRO337)   [view usage] : c.69.1.21 |alpha/beta-Hydrolases |alpha/beta-Hydrolases |PepX catalytic domain-like |Alpha-amino acid ester hydrolase |Xanthomonas citri [TaxId: 346]
 d1fbqa_ :   (PRO195)  (ASN227)   [view usage] : a.4.5.22 |DNA/RNA-binding 3-helical bundle |"Winged helix" DNA-binding domain |Heat-shock transcription factor |Heat-shock transcription factor |Milk yeast (Kluyveromyces lactis) [TaxId: 28985]
 d1d2na_ :   (LYS657)  (PRO676)   [view usage] : c.37.1.20 |P-loop containing nucleoside triphosphate hydrolases |P-loop containing nucleoside triphosphate hydrolases |Extended AAA-ATPase domain |Hexamerization domain of N-ethylmalemide-sensitive fusion (NSF) protein |Chinese hamster (Cricetulus griseus) [TaxId: 10029]
 d2ahmg1 :   (GLN173)  (LEU194)   [view usage] : d.302.1.1 |Coronavirus NSP8-like |Coronavirus NSP8-like |Coronavirus NSP8-like |Nonstructural protein 8, NSP8 |SARS coronavirus [TaxId: 227859]
 d4ixtb_ :   (SER189)  (GLN214)   [view usage] : c.2.1.2 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |Tyrosine-dependent oxidoreductases |automated matches |Rhizobium radiobacter [TaxId: 358]
 d1d1jb_ :    (THR43)   (GLY66)   [view usage] : d.110.1.1 |Profilin-like |Profilin (actin-binding protein) |Profilin (actin-binding protein) |Profilin (actin-binding protein) |Human (Homo sapiens), isoform II [TaxId: 9606]
 d3e11a1 :     (ASP5)   (ASP37)   [view usage] : d.92.1.17 |Zincin-like |Metalloproteases ("zincins"), catalytic domain |TTHA0227-like |Uncharacterized protein Acel_2062 |Acidothermus cellulolyticus [TaxId: 28049]
 d1ugqa_ :   (GLU128)  (SER162)   [view usage] : d.149.1.1 |Nitrile hydratase alpha chain |Nitrile hydratase alpha chain |Nitrile hydratase alpha chain |Cobalt-containing nitrile hydratase |Pseudonocardia thermophila [TaxId: 1848]
 d1t82a_ :     (MSE1)   (SER28)   [view usage] : d.38.1.5 |Thioesterase/thiol ester dehydrase-isomerase |Thioesterase/thiol ester dehydrase-isomerase |PaaI/YdiI-like |Putative thioesterase SO4397 |Shewanella oneidensis [TaxId: 70863]
 d2avwa_ :   (PHE172)  (ASP226)   [view usage] : d.3.1.12 |Cysteine proteinases |Cysteine proteinases |IgG-specific endopeptidase IdeS (Sib38) |automated matches |Streptococcus pyogenes [TaxId: 293653]
 d1vb3a1 :   (PHE186)  (ASN212)   [view usage] : c.79.1.1 |Tryptophan synthase beta subunit-like PLP-dependent enzymes |Tryptophan synthase beta subunit-like PLP-dependent enzymes |Tryptophan synthase beta subunit-like PLP-dependent enzymes |Threonine synthase |Escherichia coli [TaxId: 562]
 d2ipla_ :   (LYS113)  (GLU149)   [view usage] : c.93.1.1 |Periplasmic binding protein-like I |Periplasmic binding protein-like I |L-arabinose binding protein-like |Galactose/glucose-binding protein |Escherichia coli [TaxId: 562]
 d3lmsa_ :    (TRP73)  (VAL110)   [view usage] : c.56.5.0 |Phosphorylase/hydrolase-like |Zn-dependent exopeptidases |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d2dmfa1 :    (VAL12)   (GLY35)   [view usage] : d.20.1.3 |UBC-like |UBC-like |RWD domain |E3 ubiquitin-protein ligase RNF25 |Human (Homo sapiens) [TaxId: 9606]
 d1f2ka_ :  (SER1038) (ALA1063)   [view usage] : d.110.1.1 |Profilin-like |Profilin (actin-binding protein) |Profilin (actin-binding protein) |Profilin (actin-binding protein) |Acanthamoeba castellanii [TaxId: 5755]
 d1qnda_ :     (ALA9)   (LYS40)   [view usage] : d.106.1.1 |SCP-like |SCP-like |Sterol carrier protein, SCP |Sterol carrier protein 2 (SCP2) |Human (Homo sapiens) [TaxId: 9606]
 d1d1jc_ :    (THR43)   (GLY66)   [view usage] : d.110.1.1 |Profilin-like |Profilin (actin-binding protein) |Profilin (actin-binding protein) |Profilin (actin-binding protein) |Human (Homo sapiens), isoform II [TaxId: 9606]
 d4cbyb_ :   (HIS678)  (LYS705)   [view usage] : c.42.1.2 |Arginase/deacetylase |Arginase/deacetylase |Histone deacetylase, HDAC |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d3ckma1 :   (ALA468)  (SER487)   [view usage] : c.93.1.1 |Periplasmic binding protein-like I |Periplasmic binding protein-like I |L-arabinose binding protein-like |YraM C-terminal domain |Haemophilus influenzae [TaxId: 727]
 d1prqa_ :    (THR38)   (ALA63)   [view usage] : d.110.1.1 |Profilin-like |Profilin (actin-binding protein) |Profilin (actin-binding protein) |Profilin (actin-binding protein) |Acanthamoeba castellanii [TaxId: 5755]
 d1t82c_ :     (ASP2)   (SER28)   [view usage] : d.38.1.5 |Thioesterase/thiol ester dehydrase-isomerase |Thioesterase/thiol ester dehydrase-isomerase |PaaI/YdiI-like |Putative thioesterase SO4397 |Shewanella oneidensis [TaxId: 70863]
 d2fvya_ :   (LYS113)  (GLU149)   [view usage] : c.93.1.1 |Periplasmic binding protein-like I |Periplasmic binding protein-like I |L-arabinose binding protein-like |Galactose/glucose-binding protein |Escherichia coli [TaxId: 562]
 d2avwb_ :   (PRO173)  (ASP226)   [view usage] : d.3.1.12 |Cysteine proteinases |Cysteine proteinases |IgG-specific endopeptidase IdeS (Sib38) |automated matches |Streptococcus pyogenes [TaxId: 293653]
 d1mzoa_ :   (GLU713)  (ARG731)   [view usage] : c.7.1.1 |PFL-like glycyl radical enzymes |PFL-like glycyl radical enzymes |PFL-like |Pyruvate formate-lyase, PFL |Escherichia coli [TaxId: 562]
 d2arva_ :    (SER57)   (CYS81)   [view usage] : g.17.1.2 |Cystine-knot cytokines |Cystine-knot cytokines |Transforming growth factor (TGF)-beta |Activin A (Inhibin beta A) |Human (Homo sapiens) [TaxId: 9606]
 d2xt0a_ :   (ASP123)  (ASN147)   [view usage] : c.69.1.0 |alpha/beta-Hydrolases |alpha/beta-Hydrolases |automated matches |automated matches |Plesiocystis pacifica [TaxId: 191768]
 d4cbyd_ :   (HIS678)  (LYS705)   [view usage] : c.42.1.2 |Arginase/deacetylase |Arginase/deacetylase |Histone deacetylase, HDAC |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1jkma_ :   (SER202)  (ILE231)   [view usage] : c.69.1.2 |alpha/beta-Hydrolases |alpha/beta-Hydrolases |Carboxylesterase |Carboxylesterase |Bacillus subtilis, brefeldin A esterase [TaxId: 1423]
 d1d1ja_ :    (PRO44)   (GLY66)   [view usage] : d.110.1.1 |Profilin-like |Profilin (actin-binding protein) |Profilin (actin-binding protein) |Profilin (actin-binding protein) |Human (Homo sapiens), isoform II [TaxId: 9606]

List of distinct SCOP folds where this concept is used (in one or more of its domains):
  c.69,    c.94,     c.2,    c.79,    c.56,    d.92,    c.77,    c.93,    c.42,    c.37,     c.7,     d.3,    d.20,   d.110,   d.278,    d.38,   d.106,     a.4,    d.90,   d.145,  
e.26, b.7, g.17, d.308, g.7, d.149, d.302