Protein Concepts Dictionary

Tableau information

Concept source:  d3ak4a_  amino acid (a.a.) range (PRO228)(THR254)

nSSEs in this Concept: 3

String of secondary struct.elems. (SSEs) defining this concept: HHE

Each SSE's a.a.range: (start resi) (end resi) SSEtype (H=Helix; E=Strand) followed by a numeric SSE ID:
	  (PRO228)  (SER240) H1
	  (SER240)  (MET246) H2
	  (GLY248)  (THR254) E3

Orientation angles° of SSE-pairs; those in contact shown in bold font
          H1                   
H2      -70.5°   H2            
E3      153.5°  122.3°       
Footnote: Inferred from this concept's usages (listed below) was the angular variance of 1σ = ±11.6°  about each orientation angle shown above.

Loci of concept usages (shown as a range of a.a. residue ids) in SCOP(v2.05) domains, along with their brief legend taken from SCOP
 d2cr2a1 :   (ARG118)  (VAL144)   [view usage] : b.8.1.1 |TRAF domain-like |TRAF domain-like |MATH domain |Speckle-type poz protein SPOP |Human (Homo sapiens) [TaxId: 9606]
 d4is3c_ :   (PRO218)  (ASP244)   [view usage] : c.2.1.0 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |automated matches |automated matches |Clostridium scindens [TaxId: 29347]
 d3m7mx_ :   (ALA207)  (PHE230)   [view usage] : d.193.1.1 |Hsp33 domain |Hsp33 domain |Hsp33 domain |automated matches |Escherichia coli K-12 [TaxId: 83333]
 d2z51a1 :     (THR5)   (LEU29)   [view usage] : d.52.8.0 |Alpha-lytic protease prodomain-like |Fe-S cluster assembly (FSCA) domain-like |automated matches |automated matches |Arabidopsis thaliana
 d3so4c2 :   (SER201)  (ASN232)   [view usage] : d.130.1.0 |S-adenosylmethionine synthetase |S-adenosylmethionine synthetase |automated matches |automated matches |Entamoeba (Entamoeba histolytica) [TaxId: 5759]
 d1nfra_ :   (PRO209)  (ASP235)   [view usage] : c.2.1.2 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |Tyrosine-dependent oxidoreductases |Putative oxidoreductase Rv2002 |Mycobacterium tuberculosis [TaxId: 1773]
 d3nfla_ :   (THR578)  (LEU600)   [view usage] : b.36.1.1 |PDZ domain-like |PDZ domain-like |PDZ domain |Tyrosine-protein phosphatase non-receptor type 4, PTPN4 |Human (Homo sapiens) [TaxId: 9606]
 d1hvqa_ :   (PRO231)  (TRP255)   [view usage] : c.1.8.5 |TIM beta/alpha-barrel |(Trans)glycosidases |Type II chitinase |Hevamine A (chitinase/lysozyme) |Rubber tree (Hevea brasiliensis) [TaxId: 3981]
 d4p8ba_ :   (TYR120)  (GLY153)   [view usage] : c.94.1.0 |Periplasmic binding protein-like II |Periplasmic binding protein-like II |automated matches |automated matches |Cupriavidus necator [TaxId: 381666]
 d3vzqa_ :   (ILE220)  (ASN240)   [view usage] : c.2.1.0 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |automated matches |automated matches |Cupriavidus necator [TaxId: 381666]
 d3f1la_ :   (THR216)  (GLN243)   [view usage] : c.2.1.0 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |automated matches |automated matches |Escherichia coli K-12 [TaxId: 83333]
 d3f1lb_ :   (THR216)  (GLN243)   [view usage] : c.2.1.0 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |automated matches |automated matches |Escherichia coli K-12 [TaxId: 83333]
 d3gr6d_ :   (GLN223)  (ASP249)   [view usage] : c.2.1.2 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |Tyrosine-dependent oxidoreductases |Enoyl-ACP reductase |Staphylococcus aureus [TaxId: 1280]
 d3vofa_ :   (GLY118)  (LEU147)   [view usage] : c.6.1.0 |7-stranded beta/alpha barrel |Glycosyl hydrolases family 6, cellulases |automated matches |automated matches |Inky cap fungus (Coprinopsis cinerea) [TaxId: 5346]
 d2bgka1 :   (ALA233)  (ASP259)   [view usage] : c.2.1.2 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |Tyrosine-dependent oxidoreductases |Rhizome secoisolariciresinol dehydrogenase |Mayapple (Podophyllum peltatum) [TaxId: 35933]
 d4loja_ :   (ALA155)  (LEU203)   [view usage] : d.387.1.1 |STING C-terminal-like |STING, TM173 CTD-like |Tyrosinase cofactor MelC1 |automated matches |Mouse (Mus musculus) [TaxId: 10090]
 d4e4ya_ :   (PRO209)  (ASP235)   [view usage] : c.2.1.0 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |automated matches |automated matches |Francisella tularensis [TaxId: 177416]
 d2hgjg1 :     (LEU3)   (VAL37)   [view usage] : d.77.1.1 |RL5-like |RL5-like |Ribosomal protein L5 |Ribosomal protein L5 |Thermus thermophilus [TaxId: 274]
 d1r9la_ :   (ASN110)  (THR134)   [view usage] : c.94.1.1 |Periplasmic binding protein-like II |Periplasmic binding protein-like II |Phosphate binding protein-like |Glycine betaine-binding periplasmic protein ProX |Escherichia coli [TaxId: 562]
 d1fn9a_ :    (ARG78)  (ASN132)   [view usage] : d.196.1.1 |Outer capsid protein sigma 3 |Outer capsid protein sigma 3 |Outer capsid protein sigma 3 |Outer capsid protein sigma 3 |Reovirus [TaxId: 10891]
 d1hk8a_ :    (ASP67)   (CYS79)   [view usage] : c.7.1.3 |PFL-like glycyl radical enzymes |PFL-like glycyl radical enzymes |Class III anaerobic ribonucleotide reductase NRDD subunit |Class III anaerobic ribonucleotide reductase NRDD subunit |Bacteriophage T4 [TaxId: 10665]
 d3d2ud1 :    (PRO45)   (SER64)   [view usage] : b.1.1.4 |Immunoglobulin-like beta-sandwich |Immunoglobulin |I set domains |Ligand binding domain of lir-1 (ilt2) |Human (Homo sapiens) [TaxId: 9606]
 d3d9sc_ :   (SER160)  (ASN185)   [view usage] : f.19.1.0 |Aquaporin-like |Aquaporin-like |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1byqa_ :   (GLU199)  (GLU223)   [view usage] : d.122.1.1 |ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase |ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase |Heat shock protein 90, HSP90, N-terminal domain |HSP90 |Human (Homo sapiens) [TaxId: 9606]
 d2e7ga1 :    (GLU88)  (THR130)   [view usage] : d.52.7.1 |Alpha-lytic protease prodomain-like |Ribosome-binding factor A, RbfA |Ribosome-binding factor A, RbfA |Ribosome-binding factor A, RbfA |Human (Homo sapiens) [TaxId: 9606]
 d2kzfa_ :    (THR59)   (GLU97)   [view usage] : d.52.7.0 |Alpha-lytic protease prodomain-like |Ribosome-binding factor A, RbfA |automated matches |automated matches |Thermotoga maritima [TaxId: 2336]
 d4jp2a_ :   (VAL213)  (ASP233)   [view usage] : c.2.1.0 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |automated matches |automated matches |Thermus thermophilus HB8 [TaxId: 300852]
 d4nbua_ :   (PRO219)  (ASP245)   [view usage] : c.2.1.0 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |automated matches |automated matches |Bacillus sp. [TaxId: 161544]
 d1h2tc1 :   (LYS208)  (GLU227)   [view usage] : a.118.1.14 |alpha-alpha superhelix |ARM repeat |MIF4G domain-like |CBP80, 80KDa nuclear cap-binding protein |Human (Homo sapiens) [TaxId: 9606]
 d3ucxa_ :   (THR227)  (ASN254)   [view usage] : c.2.1.0 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |automated matches |automated matches |Mycobacterium smegmatis [TaxId: 246196]
 d3rw7d_ :   (ARG279)  (LEU298)   [view usage] : c.10.2.3 |Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) |L domain-like |mRNA export factor tap |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d3exec_ :   (SER101)  (LYS129)   [view usage] : c.36.1.11 |Thiamin diphosphate-binding fold (THDP-binding) |Thiamin diphosphate-binding fold (THDP-binding) |Branched-chain alpha-keto acid dehydrogenase PP module |E1-beta subunit of pyruvate dehydrogenase (PP module) |Human (Homo sapiens) [TaxId: 9606]
 d2b51a1 :   (ILE231)  (ASP251)   [view usage] : d.218.1.10 |Nucleotidyltransferase |Nucleotidyltransferase |RNA editing terminal uridyl transferase 2, RET2, catalytic domain |RNA editing terminal uridyl transferase 2, TUTase 2, RET2 |Trypanosome (Trypanosoma brucei) [TaxId: 5691]
 d4jhla_ :    (VAL66)   (MSE88)   [view usage] : c.23.10.0 |Flavodoxin-like |SGNH hydrolase |automated matches |automated matches |Geobacillus stearothermophilus [TaxId: 1422]
 d1neza2 :    (PRO57)   (TYR99)   [view usage] : d.19.1.1 |MHC antigen-recognition domain |MHC antigen-recognition domain |MHC antigen-recognition domain |Class I MHC, alpha-1 and alpha-2 domains |Mouse (Mus musculus), tla(c), H-2 class [TaxId: 10090]
 d4l4pa_ :    (THR28)   (PRO49)   [view usage] : c.1.8.0 |TIM beta/alpha-barrel |(Trans)glycosidases |automated matches |automated matches |Caldicellulosiruptor bescii [TaxId: 521460]
 d3ewjb_ :   (VAL314)  (TYR340)   [view usage] : d.92.1.10 |Zincin-like |Metalloproteases ("zincins"), catalytic domain |TNF-alpha converting enzyme, TACE, catalytic domain |TNF-alpha converting enzyme, TACE, catalytic domain |Human (Homo sapiens) [TaxId: 9606]
 d2omob_ :    (THR68)   (TYR95)   [view usage] : d.58.4.11 |Ferredoxin-like |Dimeric alpha+beta barrel |PA3566-like |Hypothetical protein NE0621 |Nitrosomonas europaea [TaxId: 915]
 d4a19x_ :    (GLU48)   (GLU80)   [view usage] : i.1.1.2 |Ribosome and ribosomal fragments |Ribosome and ribosomal fragments |Large subunit |Eukaryotic, cytoplasmic (60S subunit) |Tetrahymena thermophila [TaxId: 5911]
 d1wg6a_ :    (ASN93)  (SER122)   [view usage] : b.36.1.1 |PDZ domain-like |PDZ domain-like |PDZ domain |Partitioning-defective 3-like protein, PAR3-L (RIKEN cDNA 2810455b10) |Mouse (Mus musculus) [TaxId: 10090]
 d4n4ub_ :   (SER110)  (PRO143)   [view usage] : c.94.1.0 |Periplasmic binding protein-like II |Periplasmic binding protein-like II |automated matches |automated matches |Bordetella bronchiseptica [TaxId: 257310]
 d2ktbb_ :   (SER213)  (ASP229)   [view usage] : a.29.2.0 |Bromodomain-like |Bromodomain |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1wkvb_ :    (ASN39)   (ASP62)   [view usage] : c.79.1.1 |Tryptophan synthase beta subunit-like PLP-dependent enzymes |Tryptophan synthase beta subunit-like PLP-dependent enzymes |Tryptophan synthase beta subunit-like PLP-dependent enzymes |O-acetylserine sulfhydrylase (Cysteine synthase) |Aeropyrum pernix [TaxId: 56636]
 d3a28a_ :   (PRO226)  (ASP252)   [view usage] : c.2.1.0 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |automated matches |automated matches |Brevibacterium saccharolyticum [TaxId: 1718]
 d1rkia1 :    (LEU48)   (ASP71)   [view usage] : d.308.1.2 |THUMP domain |THUMP domain-like |PAE0736-like |Hypothetical protein PAE0736 |Pyrobaculum aerophilum [TaxId: 13773]
 d1zvfb_ :     (ILE9)   (HIS30)   [view usage] : b.82.1.0 |Double-stranded beta-helix |RmlC-like cupins |automated matches |automated matches |Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]
 d2ftrb_ :    (ASP69)  (MSE105)   [view usage] : d.58.4.15 |Ferredoxin-like |Dimeric alpha+beta barrel |EthD-like |Hypothetical protein BH0200 |Bacillus halodurans [TaxId: 86665]
 d1iyfa_ :    (ARG51)   (ARG72)   [view usage] : d.15.1.1 |beta-Grasp (ubiquitin-like) |Ubiquitin-like |Ubiquitin-related |Ubiquitin-like domain of parkin |Human (Homo sapiens) [TaxId: 9606]
 d4lojb_ :   (HIS156)  (LEU203)   [view usage] : d.387.1.1 |STING C-terminal-like |STING, TM173 CTD-like |Tyrosinase cofactor MelC1 |automated matches |Mouse (Mus musculus) [TaxId: 10090]
 d2fv5b_ :   (ASP313)  (TYR340)   [view usage] : d.92.1.10 |Zincin-like |Metalloproteases ("zincins"), catalytic domain |TNF-alpha converting enzyme, TACE, catalytic domain |TNF-alpha converting enzyme, TACE, catalytic domain |Human (Homo sapiens) [TaxId: 9606]
 d1l9ga_ :     (ARG4)   (ASN36)   [view usage] : c.18.1.2 |Uracil-DNA glycosylase-like |Uracil-DNA glycosylase-like |Mug-like |Thermophilic uracil-DNA glycosylase |Thermotoga maritima [TaxId: 2336]
 d3refb_ :   (TRP114)  (GLY131)   [view usage] : c.37.1.0 |P-loop containing nucleoside triphosphate hydrolases |P-loop containing nucleoside triphosphate hydrolases |automated matches |automated matches |Entamoeba (Entamoeba histolytica) [TaxId: 5759]
 d2idbb2 :   (ASP327)  (GLU359)   [view usage] : d.333.1.1 |UbiD C-terminal domain-like |UbiD C-terminal domain-like |UbiD C-terminal domain-like |3-octaprenyl-4-hydroxybenzoate carboxy-lyase UbiD |Escherichia coli [TaxId: 562]
 d4orsa_ :    (ASN51)   (PRO71)   [view usage] : b.60.1.0 |Lipocalins |Lipocalins |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d3e11b_ :     (ASP5)   (VAL35)   [view usage] : d.92.1.17 |Zincin-like |Metalloproteases ("zincins"), catalytic domain |TTHA0227-like |Uncharacterized protein Acel_2062 |Acidothermus cellulolyticus [TaxId: 28049]
 d3f1ka_ :   (THR216)  (GLN243)   [view usage] : c.2.1.0 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |automated matches |automated matches |Escherichia coli K-12 [TaxId: 83333]
 d1flka1 :   (GLN476)  (ASP497)   [view usage] : b.8.1.1 |TRAF domain-like |TRAF domain-like |MATH domain |TNF receptor associated factor 3 (TRAF3) |Human (Homo sapiens) [TaxId: 9606]
 d1av4a3 :   (LEU101)  (SER138)   [view usage] : d.17.2.1 |Cystatin-like |Amine oxidase N-terminal region |Amine oxidase N-terminal region |Copper amine oxidase, domains 1 and 2 |Arthrobacter globiformis [TaxId: 1665]
 d2oyna1 :    (GLY18)   (LYS47)   [view usage] : b.43.5.2 |Reductase/isomerase/elongation factor common domain |Riboflavin kinase-like |CTP-dependent riboflavin kinase-like |CTP-dependent riboflavin kinase, Rfk |Methanococcus jannaschii [TaxId: 2190]
 d2wyva_ :   (GLN223)  (ASP249)   [view usage] : c.2.1.2 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |Tyrosine-dependent oxidoreductases |automated matches |Thermus thermophilus HB8 [TaxId: 300852]
 d3pjfb_ :   (ILE222)  (ASP248)   [view usage] : c.2.1.2 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |Tyrosine-dependent oxidoreductases |automated matches |Escherichia coli K-12 [TaxId: 83333]
 d3regb_ :   (TRP114)  (GLY131)   [view usage] : c.37.1.0 |P-loop containing nucleoside triphosphate hydrolases |P-loop containing nucleoside triphosphate hydrolases |automated matches |automated matches |Entamoeba (Entamoeba histolytica) [TaxId: 5759]
 d2ivda2 :   (HIS346)  (MET365)   [view usage] : d.16.1.5 |FAD-linked reductases, C-terminal domain |FAD-linked reductases, C-terminal domain |L-aminoacid/polyamine oxidase |Protoporphyrinogen oxidase |Myxococcus xanthus [TaxId: 34]
 d1f48a1 :   (ALA112)  (ASP142)   [view usage] : c.37.1.10 |P-loop containing nucleoside triphosphate hydrolases |P-loop containing nucleoside triphosphate hydrolases |Nitrogenase iron protein-like |Arsenite-translocating ATPase ArsA |Escherichia coli [TaxId: 562]
 d2ftra1 :    (ASP69)  (ASP106)   [view usage] : d.58.4.15 |Ferredoxin-like |Dimeric alpha+beta barrel |EthD-like |Hypothetical protein BH0200 |Bacillus halodurans [TaxId: 86665]
 d3gr6g_ :   (GLN223)  (ASP249)   [view usage] : c.2.1.2 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |Tyrosine-dependent oxidoreductases |Enoyl-ACP reductase |Staphylococcus aureus [TaxId: 1280]
 d3vaya_ :   (PHE107)  (ASN128)   [view usage] : c.108.1.0 |HAD-like |HAD-like |automated matches |automated matches |Pseudomonas syringae [TaxId: 223283]
 d2ddfb_ :   (ASP313)  (TYR340)   [view usage] : d.92.1.10 |Zincin-like |Metalloproteases ("zincins"), catalytic domain |TNF-alpha converting enzyme, TACE, catalytic domain |TNF-alpha converting enzyme, TACE, catalytic domain |Human (Homo sapiens) [TaxId: 9606]
 d2wyuc_ :   (GLN223)  (ASP249)   [view usage] : c.2.1.2 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |Tyrosine-dependent oxidoreductases |automated matches |Thermus thermophilus HB8 [TaxId: 300852]
 d2omoa1 :    (LEU72)   (GLY92)   [view usage] : d.58.4.11 |Ferredoxin-like |Dimeric alpha+beta barrel |PA3566-like |Hypothetical protein NE0621 |Nitrosomonas europaea [TaxId: 915]
 d1i13a_ :    (THR14)   (LEU51)   [view usage] : c.61.1.1 |PRTase-like |PRTase-like |Phosphoribosyltransferases (PRTases) |Hypoxanthine PRTase |Trypanosoma cruzi [TaxId: 5693]
 d1ipea_ :   (MET231)  (ASP251)   [view usage] : c.2.1.2 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |Tyrosine-dependent oxidoreductases |Tropinone reductase |Jimsonweed (Datura stramonium), II [TaxId: 4076]
 d3i1ja_ :   (ALA219)  (GLN246)   [view usage] : c.2.1.0 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |automated matches |automated matches |Pseudomonas syringae [TaxId: 323]
 d2pgca1 :   (MSE172)  (ILE205)   [view usage] : d.58.4.23 |Ferredoxin-like |Dimeric alpha+beta barrel |Marine metagenome family DABB3 |Uncharacterized protein GOS_2596953 |Environmental samples
 d1jkma_ :   (GLY173)  (SER202)   [view usage] : c.69.1.2 |alpha/beta-Hydrolases |alpha/beta-Hydrolases |Carboxylesterase |Carboxylesterase |Bacillus subtilis, brefeldin A esterase [TaxId: 1423]
 d3raja_ :   (ASP252)  (ASN277)   [view usage] : c.23.14.3 |Flavodoxin-like |N-(deoxy)ribosyltransferase-like |ADP ribosyl cyclase-like |ADP ribosyl cyclase |Human (Homo sapiens) [TaxId: 9606]
 d1ck4a_ :   (MET225)  (VAL255)   [view usage] : c.62.1.1 |vWA-like |vWA-like |Integrin A (or I) domain |Integrin alpha1-beta1 |Norway rat (Rattus norvegicus) [TaxId: 10116]
 d4r9va_ :   (ARG470)  (ALA497)   [view usage] : c.87.1.0 |UDP-Glycosyltransferase/glycogen phosphorylase |UDP-Glycosyltransferase/glycogen phosphorylase |automated matches |automated matches |Photobacterium damselae [TaxId: 38293]

List of distinct SCOP folds where this concept is used (in one or more of its domains):
   c.1,    c.10,    b.82,    c.69,    c.94,     c.2,     c.6,    d.58,     i.1,   a.118,   c.108,    c.79,    d.92,   d.122,    c.23,    c.37,    c.36,     c.7,    c.18,    b.60,  
c.87, c.62, b.1, d.17, d.19, c.61, d.193, d.15, b.43, d.16, a.29, f.19, d.218, d.130, b.36, d.52, d.308, d.333, d.77, b.8,
d.387, d.196