Protein Concepts Dictionary

Tableau information

Concept source:  d2g7ea_  amino acid (a.a.) range (PHE24)(LEU59)

nSSEs in this Concept: 3

String of secondary struct.elems. (SSEs) defining this concept: HEE

Each SSE's a.a.range: (start resi) (end resi) SSEtype (H=Helix; E=Strand) followed by a numeric SSE ID:
	   (PHE24)   (ARG36) H1
	   (GLU47)   (GLY52) E2
	   (LYS53)   (LEU59) E3

Orientation angles° of SSE-pairs; those in contact shown in bold font
          H1                   
E2     -126.5°   E2            
E3       56.2°  157.1°       
Footnote: Inferred from this concept's usages (listed below) was the angular variance of 1σ = ±7.2°  about each orientation angle shown above.

Loci of concept usages (shown as a range of a.a. residue ids) in SCOP(v2.05) domains, along with their brief legend taken from SCOP
 d2uz5a_ :     (ASN2)   (LYS35)   [view usage] : d.26.1.0 |FKBP-like |FKBP-like |automated matches |automated matches |Legionella pneumophila [TaxId: 446]
 d1s2ha_ :    (GLY10)   (ASP58)   [view usage] : d.135.1.1 |The spindle assembly checkpoint protein mad2 |The spindle assembly checkpoint protein mad2 |The spindle assembly checkpoint protein mad2 |The spindle assembly checkpoint protein mad2 |Human (Homo sapiens) [TaxId: 9606]
 d1nyoa_ :   (SER108)  (GLY136)   [view usage] : b.118.1.1 |FAS1 domain |FAS1 domain |FAS1 domain |Immunogenic protein MPT70 |Mycobacterium tuberculosis [TaxId: 1773]
 d2xzm7_ :    (ARG47)   (LEU68)   [view usage] : i.1.1.3 |Ribosome and ribosomal fragments |Ribosome and ribosomal fragments |Small subunit |Eukaryotic, cytoplasmic (40S subunit) |Tetrahymena thermophila [TaxId: 5911]
 d3o2ma_ :    (ASN63)  (ASP112)   [view usage] : d.144.1.7 |Protein kinase-like (PK-like) |Protein kinase-like (PK-like) |Protein kinases, catalytic subunit |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1ouoa_ :    (SER23)   (ASN58)   [view usage] : d.4.1.6 |His-Me finger endonucleases |His-Me finger endonucleases |Endonuclease I |Periplasmic endonuclease Vvn |Vibrio vulnificus [TaxId: 672]
 d1iaih2 :   (ASN163)  (THR190)   [view usage] : b.1.1.2 |Immunoglobulin-like beta-sandwich |Immunoglobulin |C1 set domains (antibody constant domain-like) |Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma |Mouse (Mus musculus) [TaxId: 10090]
 d3n0sa_ :   (LYS112)  (GLY137)   [view usage] : c.140.1.0 |TTHA0583/YokD-like |TTHA0583/YokD-like |automated matches |automated matches |Bacillus anthracis [TaxId: 198094]
 d3h3ub2 :   (SER187)  (SER214)   [view usage] : a.4.5.0 |DNA/RNA-binding 3-helical bundle |"Winged helix" DNA-binding domain |automated matches |automated matches |Mycobacterium tuberculosis [TaxId: 83332]
 d2kmta_ :    (PRO42)   (THR69)   [view usage] : b.34.6.1 |SH3-like barrel |Cell growth inhibitor/plasmid maintenance toxic component |CcdB |CcdB |Vibrio fischeri [TaxId: 668]
 d3k5la1 :   (VAL225)  (LYS270)   [view usage] : c.55.3.5 |Ribonuclease H-like motif |Ribonuclease H-like |DnaQ-like 3'-5' exonuclease |automated matches |Escherichia coli [TaxId: 562]
 d3d0sb2 :   (GLU189)  (SER214)   [view usage] : a.4.5.0 |DNA/RNA-binding 3-helical bundle |"Winged helix" DNA-binding domain |automated matches |automated matches |Mycobacterium tuberculosis [TaxId: 1773]
 d1xs5a_ :   (SER114)  (ARG150)   [view usage] : c.94.1.1 |Periplasmic binding protein-like II |Periplasmic binding protein-like II |Phosphate binding protein-like |Putative lipoprotein (NlpA family) |Treponema pallidum [TaxId: 160]
 d1g9ng_ :   (ASP368)  (ASN386)   [view usage] : d.172.1.1 |gp120 core |gp120 core |gp120 core |gp120 core |Human immunodeficiency virus type 1 [TaxId: 11676]
 d2nygd_ :   (GLY113)  (GLY139)   [view usage] : c.140.1.2 |TTHA0583/YokD-like |TTHA0583/YokD-like |Aminoglycoside 3-N-acetyltransferase-like |Uncharacterized protein YokD |Bacillus subtilis [TaxId: 1423]
 d3e5xa2 :   (HIS191)  (ASN218)   [view usage] : a.4.5.4 |DNA/RNA-binding 3-helical bundle |"Winged helix" DNA-binding domain |CAP C-terminal domain-like |Chlorophenol reduction protein CprK |Desulfitobacterium hafniense [TaxId: 49338]
 d1li4a1 :   (VAL308)  (ARG329)   [view usage] : c.2.1.4 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |Formate/glycerate dehydrogenases, NAD-domain |S-adenosylhomocystein hydrolase |Human (Homo sapiens) [TaxId: 9606]
 d4fp5d_ :    (ASP57)   (ALA98)   [view usage] : b.40.2.1 |OB-fold |Bacterial enterotoxins |Bacterial AB5 toxins, B-subunits |automated matches |Escherichia coli [TaxId: 562]
 d2g7ea_ :    (PHE24)   (LEU59)   [view usage] : d.4.1.6 |His-Me finger endonucleases |His-Me finger endonucleases |Endonuclease I |automated matches |Vibrio cholerae [TaxId: 666]
 d1e9sb_ :   (PRO464)  (LYS487)   [view usage] : c.37.1.11 |P-loop containing nucleoside triphosphate hydrolases |P-loop containing nucleoside triphosphate hydrolases |RecA protein-like (ATPase-domain) |Bacterial conjugative coupling protein TrwB |Escherichia coli [TaxId: 562]
 d4a17w_ :    (GLU53)   (ASP98)   [view usage] : i.1.1.2 |Ribosome and ribosomal fragments |Ribosome and ribosomal fragments |Large subunit |Eukaryotic, cytoplasmic (60S subunit) |Tetrahymena thermophila [TaxId: 5911]
 d1ekma1 :   (GLY324)  (LYS360)   [view usage] : b.30.2.1 |Supersandwich |Amine oxidase catalytic domain |Amine oxidase catalytic domain |Copper amine oxidase, domain 3 |Yeast (Hansenula polymorpha) [TaxId: 4905]
 d1hcua_ :   (SER451)  (SER491)   [view usage] : a.102.2.1 |alpha/alpha toroid |Seven-hairpin glycosidases |Class I alpha-1;2-mannosidase, catalytic domain |Class I alpha-1;2-mannosidase, catalytic domain |Trichoderma reesei [TaxId: 51453]
 d1by5a_ :   (SER326)  (ASP394)   [view usage] : f.4.3.3 |Transmembrane beta-barrels |Porins |Ligand-gated protein channel |Ferric hydroxamate uptake receptor FhuA |Escherichia coli [TaxId: 562]
 d3r95a_ :     (THR8)   (TYR22)   [view usage] : d.108.1.0 |Acyl-CoA N-acyltransferases (Nat) |Acyl-CoA N-acyltransferases (Nat) |automated matches |automated matches |Escherichia coli [TaxId: 562]
 d3bz6a1 :    (GLN66)   (HIS95)   [view usage] : a.4.5.75 |DNA/RNA-binding 3-helical bundle |"Winged helix" DNA-binding domain |PSPTO2686-like |Hypothetical protein PSPTO2686 |Pseudomonas syringae pv. tomato [TaxId: 323]
 d1klka_ :    (GLY58)   (GLY89)   [view usage] : c.71.1.1 |Dihydrofolate reductase-like |Dihydrofolate reductase-like |Dihydrofolate reductases |Dihydrofolate reductases, eukaryotic type |Fungus (Pneumocystis carinii) [TaxId: 4754]
 d1go4d_ :    (THR12)   (ASP58)   [view usage] : d.135.1.1 |The spindle assembly checkpoint protein mad2 |The spindle assembly checkpoint protein mad2 |The spindle assembly checkpoint protein mad2 |The spindle assembly checkpoint protein mad2 |Human (Homo sapiens) [TaxId: 9606]
 d3neya_ :   (SER335)  (LYS362)   [view usage] : c.37.1.0 |P-loop containing nucleoside triphosphate hydrolases |P-loop containing nucleoside triphosphate hydrolases |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1hcuc_ :   (PHE452)  (SER491)   [view usage] : a.102.2.1 |alpha/alpha toroid |Seven-hairpin glycosidases |Class I alpha-1;2-mannosidase, catalytic domain |Class I alpha-1;2-mannosidase, catalytic domain |Trichoderma reesei [TaxId: 51453]
 d1h16a_ :   (GLY528)  (GLY561)   [view usage] : c.7.1.1 |PFL-like glycyl radical enzymes |PFL-like glycyl radical enzymes |PFL-like |Pyruvate formate-lyase, PFL |Escherichia coli [TaxId: 562]
 d1kywa1 :    (LEU81)  (LEU108)   [view usage] : a.4.5.29 |DNA/RNA-binding 3-helical bundle |"Winged helix" DNA-binding domain |Plant O-methyltransferase, N-terminal domain |Caffeic acid/5-hydroxyferulic acid 3/5-O-methyltransferase |Alfalfa (Medicago sativa) [TaxId: 3879]
 d4fnfa_ :    (TYR55)   (ALA98)   [view usage] : b.40.2.1 |OB-fold |Bacterial enterotoxins |Bacterial AB5 toxins, B-subunits |automated matches |Escherichia coli [TaxId: 562]
 d1dyra_ :    (ARG59)   (GLY89)   [view usage] : c.71.1.1 |Dihydrofolate reductase-like |Dihydrofolate reductase-like |Dihydrofolate reductases |Dihydrofolate reductases, eukaryotic type |Fungus (Pneumocystis carinii) [TaxId: 4754]
 d1l0li_ :     (SER3)   (LEU26)   [view usage] : d.184.1.3 |Non-globular alpha+beta subunits of globular proteins |Non-globular alpha+beta subunits of globular proteins |Ubiquinol-cytochrome c reductase 8 kDa protein |Ubiquinol-cytochrome c reductase 8 kDa protein |Cow (Bos taurus) [TaxId: 9913]
 d1oupb_ :    (SER23)   (PRO57)   [view usage] : d.4.1.6 |His-Me finger endonucleases |His-Me finger endonucleases |Endonuclease I |Periplasmic endonuclease Vvn |Vibrio vulnificus [TaxId: 672]
 d1c8za_ :   (LEU250)  (LEU287)   [view usage] : d.23.1.1 |Tubby C-terminal domain-like |Tubby C-terminal domain-like |Transcriptional factor tubby, C-terminal domain |Transcriptional factor tubby, C-terminal domain |Mouse (Mus musculus) [TaxId: 10090]
 d2evra2 :   (ALA145)  (LEU179)   [view usage] : d.3.1.16 |Cysteine proteinases |Cysteine proteinases |NlpC/P60 |Cell wall-associated hydrolase Spr C-terminal domain |Nostoc punctiforme [TaxId: 272131]
 d3cpfa2 :   (ASP118)  (ALA146)   [view usage] : b.40.4.0 |OB-fold |Nucleic acid-binding proteins |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1u5tc2 :   (PRO169)  (ILE199)   [view usage] : a.4.5.54 |DNA/RNA-binding 3-helical bundle |"Winged helix" DNA-binding domain |Vacuolar sorting protein domain |Vacuolar protein sorting-associated protein VPS25 |Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]
 d1s31a_ :   (LEU306)  (LEU343)   [view usage] : d.23.1.1 |Tubby C-terminal domain-like |Tubby C-terminal domain-like |Transcriptional factor tubby, C-terminal domain |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1bkba2 :   (GLU110)  (ILE134)   [view usage] : b.40.4.5 |OB-fold |Nucleic acid-binding proteins |Cold shock DNA-binding domain-like |C-terminal domain of eukaryotic initiation translation factor 5a (eIF5a) |Pyrobaculum aerophilum [TaxId: 13773]
 d1hzea_ :    (PRO29)   (ASP62)   [view usage] : b.43.4.3 |Reductase/isomerase/elongation factor common domain |Riboflavin synthase domain-like |Riboflavin synthase |Riboflavin synthase |Escherichia coli [TaxId: 562]
 d2a3zb_ :   (ILE184)  (GLY218)   [view usage] : d.151.1.1 |DNase I-like |DNase I-like |DNase I-like |Deoxyribonuclease I |Cow (Bos taurus) [TaxId: 9913]
 d4fo2a_ :    (ASP57)   (ALA98)   [view usage] : b.40.2.1 |OB-fold |Bacterial enterotoxins |Bacterial AB5 toxins, B-subunits |automated matches |Escherichia coli [TaxId: 562]
 d1ufhb_ :    (ALA39)   (HIS79)   [view usage] : d.108.1.1 |Acyl-CoA N-acyltransferases (Nat) |Acyl-CoA N-acyltransferases (Nat) |N-acetyl transferase, NAT |Putative acetyltransferase YycN |Bacillus subtilis [TaxId: 1423]
 d1tzoa2 :   (PRO184)  (SER204)   [view usage] : b.179.1.1 |Anthrax protective antigen N-terminal-like |PA14-like |PA14 |PA14 |Bacillus anthracis
 d3ugja7 :  (ASP1205) (THR1249)   [view usage] : c.23.16.1 |Flavodoxin-like |Class I glutamine amidotransferase-like |Class I glutamine amidotransferases (GAT) |FGAM synthase PurL, amidotransferase domain |Salmonella enterica [TaxId: 90371]
 d1qb5d_ :    (ASP57)   (ALA98)   [view usage] : b.40.2.1 |OB-fold |Bacterial enterotoxins |Bacterial AB5 toxins, B-subunits |Heat-labile toxin |Escherichia coli, type IIB [TaxId: 562]
 d1gmwd1 :    (PRO21)   (LEU43)   [view usage] : b.107.1.1 |Urease metallochaperone UreE, N-terminal domain |Urease metallochaperone UreE, N-terminal domain |Urease metallochaperone UreE, N-terminal domain |Urease metallochaperone UreE, N-terminal domain |Klebsiella aerogenes [TaxId: 28451]
 d1kv9a2 :     (ASP4)   (LEU33)   [view usage] : b.70.1.1 |8-bladed beta-propeller |Quinoprotein alcohol dehydrogenase-like |Quinoprotein alcohol dehydrogenase-like |Quinoprotein alcohol dehydrogenase, N-terminal domain |Pseudomonas putida, hk5 [TaxId: 303]
 d1mufa2 :   (THR251)  (VAL277)   [view usage] : b.85.7.1 |beta-clip |SET domain |Histone lysine methyltransferases |Histone H3 K4-specific methyltransferase SET7/9 catalytic domain |Human (Homo sapiens) [TaxId: 9606]
 d2czjg1 :    (LEU89)  (LYS123)   [view usage] : b.111.1.1 |Small protein B (SmpB) |Small protein B (SmpB) |Small protein B (SmpB) |Small protein B (SmpB) |Thermus thermophilus [TaxId: 274]
 d4j98a_ :   (THR524)  (GLU565)   [view usage] : d.144.1.7 |Protein kinase-like (PK-like) |Protein kinase-like (PK-like) |Protein kinases, catalytic subunit |Fibroblast growth factor receptor 2 |Human (Homo sapiens) [TaxId: 9606]
 d2zmea2 :   (GLU207)  (LEU236)   [view usage] : a.4.5.0 |DNA/RNA-binding 3-helical bundle |"Winged helix" DNA-binding domain |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1peua2 :   (ILE592)  (ALA624)   [view usage] : c.7.1.2 |PFL-like glycyl radical enzymes |PFL-like glycyl radical enzymes |R1 subunit of ribonucleotide reductase, C-terminal domain |R1 subunit of ribonucleotide reductase, C-terminal domain |Salmonella typhimurium [TaxId: 90371]
 d2vnda_ :    (PHE24)   (LEU59)   [view usage] : d.4.1.6 |His-Me finger endonucleases |His-Me finger endonucleases |Endonuclease I |automated matches |Vibrio cholerae [TaxId: 666]
 d2g7fa_ :    (PHE24)   (LEU59)   [view usage] : d.4.1.6 |His-Me finger endonucleases |His-Me finger endonucleases |Endonuclease I |automated matches |Vibrio cholerae [TaxId: 666]
 d1a7aa1 :   (VAL308)  (ARG329)   [view usage] : c.2.1.4 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |Formate/glycerate dehydrogenases, NAD-domain |S-adenosylhomocystein hydrolase |Human (Homo sapiens) [TaxId: 9606]
 d1bvsa3 :    (THR31)   (SER63)   [view usage] : b.40.4.2 |OB-fold |Nucleic acid-binding proteins |DNA helicase RuvA subunit, N-terminal domain |DNA helicase RuvA subunit, N-terminal domain |Mycobacterium leprae [TaxId: 1769]
 d2ivka_ :    (PHE24)   (ASN58)   [view usage] : d.4.1.6 |His-Me finger endonucleases |His-Me finger endonucleases |Endonuclease I |automated matches |Vibrio vulnificus [TaxId: 672]
 d1cm5a_ :   (GLY528)  (GLY561)   [view usage] : c.7.1.1 |PFL-like glycyl radical enzymes |PFL-like glycyl radical enzymes |PFL-like |Pyruvate formate-lyase, PFL |Escherichia coli [TaxId: 562]
 d1b3ra1 :   (VAL307)  (LEU328)   [view usage] : c.2.1.4 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |Formate/glycerate dehydrogenases, NAD-domain |S-adenosylhomocystein hydrolase |Norway rat (Rattus norvegicus) [TaxId: 10116]
 d2hbwa2 :   (ALA145)  (LEU179)   [view usage] : d.3.1.16 |Cysteine proteinases |Cysteine proteinases |NlpC/P60 |automated matches |Anabaena variabilis [TaxId: 240292]
 d1od2b1 :  (THR1659) (LYS1691)   [view usage] : c.14.1.4 |ClpP/crotonase |ClpP/crotonase |Biotin dependent carboxylase carboxyltransferase domain |Acetyl-coenzyme A carboxylase |Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]
 d2joka_ :   (ARG142)  (PRO169)   [view usage] : a.168.1.1 |SopE-like GEF domain |SopE-like GEF domain |SopE-like GEF domain |Effector protein BopE |Burkholderia pseudomallei [TaxId: 28450]
 d2axza2 :   (GLU270)  (GLU306)   [view usage] : a.118.8.4 |alpha-alpha superhelix |TPR-like |PrgX C-terminal domain-like |automated matches |Enterococcus faecalis [TaxId: 1351]

List of distinct SCOP folds where this concept is used (in one or more of its domains):
  b.70,    c.94,     c.2,     i.1,   a.118,   c.140,    b.30,   a.102,    c.14,    c.23,     f.4,   d.144,    b.40,    c.37,     c.7,    c.55,   d.151,     d.3,    c.71,    b.85,  
b.1, d.108, b.179, b.34, a.4, b.43, d.26, d.4, d.23, d.184, b.118, d.172, a.168, d.135, b.111, b.107