Protein Concepts Dictionary

Tableau information

Concept source:  d2deba1  amino acid (a.a.) range (VAL483)(PHE516)

nSSEs in this Concept: 3

String of secondary struct.elems. (SSEs) defining this concept: EEH

Each SSE's a.a.range: (start resi) (end resi) SSEtype (H=Helix; E=Strand) followed by a numeric SSE ID:
	  (VAL483)  (ALA493) E1
	  (ARG498)  (ARG503) E2
	  (SER506)  (PHE516) H3

Orientation angles° of SSE-pairs; those in contact shown in bold font
          E1                   
E2      148.7°   E2            
H3      138.5°  -39.8°       
Footnote: Inferred from this concept's usages (listed below) was the angular variance of 1σ = ±9.5°  about each orientation angle shown above.

Loci of concept usages (shown as a range of a.a. residue ids) in SCOP(v2.05) domains, along with their brief legend taken from SCOP
 d1jawa1 :   (ASN155)  (LEU174)   [view usage] : c.55.2.1 |Ribonuclease H-like motif |Creatinase/prolidase N-terminal domain |Creatinase/prolidase N-terminal domain |Aminopeptidase P |Escherichia coli [TaxId: 562]
 d1clea_ :   (LEU502)  (PRO529)   [view usage] : c.69.1.17 |alpha/beta-Hydrolases |alpha/beta-Hydrolases |Fungal lipases |Type-B carboxylesterase/lipase |Candida cylindracea, cholesterol esterase [TaxId: 44322]
 d3su4a_ :  (LYS1155) (ARG1180)   [view usage] : b.47.1.3 |Trypsin-like serine proteases |Trypsin-like serine proteases |Viral proteases |automated matches |Hepatitis C virus subtype 1a [TaxId: 31646]
 d1u34a_ :    (ALA99)  (ILE121)   [view usage] : g.76.1.1 |Hormone receptor domain |Hormone receptor domain |Hormone receptor domain |Corticotropin releasing factor receptor 2, CRFR-2beta |Mouse (Mus musculus) [TaxId: 10090]
 d3d5by1 :    (GLY41)   (ARG73)   [view usage] : b.34.5.1 |SH3-like barrel |Translation proteins SH3-like domain |Ribosomal proteins L24p and L21e |Ribosomal proteins L24 (L24p) |Thermus thermophilus [TaxId: 274]
 d1llfa_ :   (MET503)  (PRO529)   [view usage] : c.69.1.17 |alpha/beta-Hydrolases |alpha/beta-Hydrolases |Fungal lipases |Type-B carboxylesterase/lipase |Candida cylindracea, cholesterol esterase [TaxId: 44322]
 d1ty0a1 :    (ASP31)   (LYS47)   [view usage] : b.40.2.2 |OB-fold |Bacterial enterotoxins |Superantigen toxins, N-terminal domain |Streptococcal pyrogenic exotoxin Spe-J |Streptococcus pyogenes [TaxId: 1314]
 d3ouqa1 :     (VAL6)   (TYR27)   [view usage] : a.138.1.0 |Multiheme cytochromes |Multiheme cytochromes |automated matches |automated matches |Geobacter sulfurreducens [TaxId: 35554]
 d1ki9b_ :    (SER93)  (LEU113)   [view usage] : c.37.1.1 |P-loop containing nucleoside triphosphate hydrolases |P-loop containing nucleoside triphosphate hydrolases |Nucleotide and nucleoside kinases |Adenylate kinase |Methanococcus thermolithotrophicus [TaxId: 2186]
 d4hasb_ :   (VAL172)  (GLU219)   [view usage] : d.189.1.0 |PX domain |PX domain |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1f8wa3 :   (GLN324)  (LEU349)   [view usage] : d.87.1.1 |CO dehydrogenase flavoprotein C-domain-like |FAD/NAD-linked reductases, dimerisation (C-terminal) domain |FAD/NAD-linked reductases, dimerisation (C-terminal) domain |NADH peroxidase |Enterococcus faecalis [TaxId: 1351]
 d3u5cc_ :   (LYS157)  (GLY192)   [view usage] : i.1.1.1 |Ribosome and ribosomal fragments |Ribosome and ribosomal fragments |Ribosome complexes |Eukaryotic, cytoplasmic (80S ribosome functional complex) |Saccharomyces cerevisiae [TaxId: 559292]
 d3kica_ :   (ASN540)  (THR569)   [view usage] : b.121.5.2 |Nucleoplasmin-like/VP (viral coat and capsid proteins) |ssDNA viruses |Parvoviridae-like VP |automated matches |Adeno-associated virus 3b [TaxId: 68742]
 d1pkpa1 :    (GLU84)  (GLY119)   [view usage] : d.14.1.1 |Ribosomal protein S5 domain 2-like |Ribosomal protein S5 domain 2-like |Translational machinery components |Ribosomal protein S5, C-terminal domain |Bacillus stearothermophilus [TaxId: 1422]
 d1crla_ :   (MET503)  (LEU525)   [view usage] : c.69.1.17 |alpha/beta-Hydrolases |alpha/beta-Hydrolases |Fungal lipases |Type-B carboxylesterase/lipase |Fungus (Candida rugosa), formerly Cylindracea [TaxId: 5481]
 d4fiua1 :   (SER111)  (GLY128)   [view usage] : b.19.1.2 |Viral protein domain |Viral protein domain |Influenza hemagglutinin headpiece |Hemagglutinin |Influenza A virus, different strains [TaxId: 11320]
 d4v19s_ :    (ILE90)  (LEU116)   [view usage] : i.1.1.2 |Ribosome and ribosomal fragments |Ribosome and ribosomal fragments |Large subunit |Eukaryotic, mitochondrial (54S or 39S subunit) |Pig (Sus scrofa) [TaxId: 9823]
 d1gk2a_ :   (VAL404)  (ARG452)   [view usage] : a.127.1.2 |L-aspartase-like |L-aspartase-like |HAL/PAL-like |Histidine ammonia-lyase (HAL) |Pseudomonas putida [TaxId: 303]
 d1fjge1 :    (GLU79)  (GLY114)   [view usage] : d.14.1.1 |Ribosomal protein S5 domain 2-like |Ribosomal protein S5 domain 2-like |Translational machinery components |Ribosomal protein S5, C-terminal domain |Thermus thermophilus [TaxId: 274]
 d2e9fc_ :   (ALA277)  (ALA297)   [view usage] : a.127.1.0 |L-aspartase-like |L-aspartase-like |automated matches |automated matches |Thermus thermophilus HB8 [TaxId: 300852]
 d3gc8b_ :     (GLY7)   (CYS39)   [view usage] : d.144.1.7 |Protein kinase-like (PK-like) |Protein kinase-like (PK-like) |Protein kinases, catalytic subunit |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1gz7a_ :   (MET503)  (SER527)   [view usage] : c.69.1.17 |alpha/beta-Hydrolases |alpha/beta-Hydrolases |Fungal lipases |Type-B carboxylesterase/lipase |Candida rugosa, lipase 2 isoform [TaxId: 5481]
 d4hasa_ :   (PRO177)  (ALA221)   [view usage] : d.189.1.0 |PX domain |PX domain |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1g4wr2 :   (GLY392)  (GLN411)   [view usage] : c.45.1.2 |(Phosphotyrosine protein) phosphatases II |(Phosphotyrosine protein) phosphatases II |Higher-molecular-weight phosphotyrosine protein phosphatases |SptP tyrosine phosphatase, catalytic domain |Salmonella typhimurium [TaxId: 90371]
 d2ljza_ :   (PHE125)  (SER142)   [view usage] : g.90.1.1 |E6 C-terminal domain-like |E6 C-terminal domain-like |E6 C-terminal domain-like |automated matches |Human papillomavirus [TaxId: 333760]
 d4a17m_ :   (TYR183)  (GLY206)   [view usage] : i.1.1.2 |Ribosome and ribosomal fragments |Ribosome and ribosomal fragments |Large subunit |Eukaryotic, cytoplasmic (60S subunit) |Tetrahymena thermophila [TaxId: 5911]
 d2i2to1 :    (HIS34)   (LEU62)   [view usage] : c.55.4.1 |Ribonuclease H-like motif |Translational machinery components |Ribosomal protein L18 and S11 |Ribosomal protein L18 (L18p) |Escherichia coli [TaxId: 562]
 d2w99b_ :    (VAL71)  (ALA107)   [view usage] : d.144.1.7 |Protein kinase-like (PK-like) |Protein kinase-like (PK-like) |Protein kinases, catalytic subunit |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1z24a1 :    (LYS54)   (THR83)   [view usage] : b.60.1.1 |Lipocalins |Lipocalins |Retinol binding protein-like |Insecticyanin |Tobacco hornworm (Manduca sexta) [TaxId: 7130]
 d2z1aa2 :   (PRO155)  (GLU178)   [view usage] : d.159.1.2 |Metallo-dependent phosphatases |Metallo-dependent phosphatases |5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain |5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain |Thermus thermophilus [TaxId: 274]
 d2wu9a2 :   (ARG418)  (ARG446)   [view usage] : c.95.1.0 |Thiolase-like |Thiolase-like |automated matches |automated matches |Thale cress (Arabidopsis thaliana) [TaxId: 3702]
 d1m35a1 :   (ASN155)  (LEU174)   [view usage] : c.55.2.1 |Ribonuclease H-like motif |Creatinase/prolidase N-terminal domain |Creatinase/prolidase N-terminal domain |Aminopeptidase P |Escherichia coli [TaxId: 562]
 d4f8xa_ :   (GLY309)  (GLY354)   [view usage] : c.1.8.0 |TIM beta/alpha-barrel |(Trans)glycosidases |automated matches |automated matches |Penicillium canescens [TaxId: 5083]
 d1y4zb1 :    (GLY65)   (ILE88)   [view usage] : d.58.1.5 |Ferredoxin-like |4Fe-4S ferredoxins |Ferredoxin domains from multidomain proteins |Respiratory nitrate reductase 1 beta chain |Escherichia coli [TaxId: 562]
 d3o9ma_ :   (GLN498)  (MET532)   [view usage] : c.69.1.0 |alpha/beta-Hydrolases |alpha/beta-Hydrolases |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d4juea_ :    (GLY55)   (GLY90)   [view usage] : d.20.1.1 |UBC-like |UBC-like |UBC-related |automated matches |Plasmodium falciparum [TaxId: 36329]
 d1gk3a_ :   (VAL404)  (ARG452)   [view usage] : a.127.1.2 |L-aspartase-like |L-aspartase-like |HAL/PAL-like |Histidine ammonia-lyase (HAL) |Pseudomonas putida [TaxId: 303]
 d4jk8b_ :  (ASN1804) (LEU1833)   [view usage] : c.55.3.14 |Ribonuclease H-like motif |Ribonuclease H-like |Prp8 beta-finger domain-like |Pre-mRNA-splicing factor 8, Prp8 |Human (Homo sapiens) [TaxId: 9606]
 d2h4ta1 :   (ALA484)  (PHE516)   [view usage] : c.43.1.0 |CoA-dependent acyltransferases |CoA-dependent acyltransferases |automated matches |automated matches |Norway rat (Rattus norvegicus) [TaxId: 10116]
 d1kn3a_ :   (GLY108)  (HIS159)   [view usage] : b.17.1.1 |PEBP-like |PEBP-like |Phosphatidylethanolamine binding protein |Phosphatidylethanolamine binding protein, PEBP |Mouse (Mus musculus), PEBP-2 [TaxId: 10090]
 d3pnka_ :   (PHE204)  (VAL244)   [view usage] : c.119.1.2 |DAK1/DegV-like |DAK1/DegV-like |DAK1 |automated matches |Escherichia coli K-12 [TaxId: 83333]
 d1khtb_ :    (SER93)  (LEU113)   [view usage] : c.37.1.1 |P-loop containing nucleoside triphosphate hydrolases |P-loop containing nucleoside triphosphate hydrolases |Nucleotide and nucleoside kinases |Adenylate kinase |Methanococcus voltae [TaxId: 2188]
 d1d9ua_ :    (LYS51)   (GLY82)   [view usage] : d.2.1.4 |Lysozyme-like |Lysozyme-like |Lambda lysozyme |Lambda lysozyme |Bacteriophage lambda [TaxId: 10710]
 d4hwra1 :   (ILE466)  (SER494)   [view usage] : d.104.1.1 |Class II aaRS and biotin synthetases |Class II aaRS and biotin synthetases |Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain |automated matches |Escherichia coli K-12 [TaxId: 83333]
 d2exra1 :   (ALA102)  (HIS119)   [view usage] : d.145.1.0 |FAD-binding/transporter-associated domain-like |FAD-binding/transporter-associated domain-like |automated matches |automated matches |Thale cress (Arabidopsis thaliana) [TaxId: 3702]
 d1nksa_ :    (ALA94)  (ILE114)   [view usage] : c.37.1.1 |P-loop containing nucleoside triphosphate hydrolases |P-loop containing nucleoside triphosphate hydrolases |Nucleotide and nucleoside kinases |Adenylate kinase |Sulfolobus acidocaldarius [TaxId: 2285]
 d2bspa_ :    (LYS54)   (LYS79)   [view usage] : b.80.1.1 |Single-stranded right-handed beta-helix |Pectin lyase-like |Pectate lyase-like |Pectate lyase |Bacillus subtilis [TaxId: 1423]
 d1e3qa_ :   (GLN500)  (THR535)   [view usage] : c.69.1.1 |alpha/beta-Hydrolases |alpha/beta-Hydrolases |Acetylcholinesterase-like |Acetylcholinesterase |Pacific electric ray (Torpedo californica) [TaxId: 7787]
 d2cyja1 :    (HIS20)   (HIS42)   [view usage] : c.103.1.1 |MTH938-like |MTH938-like |MTH938-like |Hypothetical protein PH1505 |Pyrococcus horikoshii [TaxId: 53953]
 d4jkab_ :  (ASN1804) (LEU1833)   [view usage] : c.55.3.14 |Ribonuclease H-like motif |Ribonuclease H-like |Prp8 beta-finger domain-like |Pre-mRNA-splicing factor 8, Prp8 |Human (Homo sapiens) [TaxId: 9606]
 d4nwla_ :   (ARG155)  (ARG180)   [view usage] : b.47.1.3 |Trypsin-like serine proteases |Trypsin-like serine proteases |Viral proteases |automated matches |Hepatitis C virus subtype 1a [TaxId: 31646]
 d2iqqa1 :   (ASN123)  (LYS158)   [view usage] : d.81.2.1 |FwdE/GAPDH domain-like |Serine metabolism enzymes domain |Serine dehydratase beta chain-like |L-serine dehydratase SdhL, N-terminal domain |Legionella pneumophila [TaxId: 446]
 d3n5id_ :   (GLU344)  (ARG369)   [view usage] : d.154.1.0 |DmpA/ArgJ-like |DmpA/ArgJ-like |automated matches |automated matches |Sphingosinicella xenopeptidilytica [TaxId: 364098]
 d2iqya_ :   (GLY108)  (HIS159)   [view usage] : b.17.1.1 |PEBP-like |PEBP-like |Phosphatidylethanolamine binding protein |automated matches |Norway rat (Rattus norvegicus) [TaxId: 10116]
 d1ebda3 :   (ALA347)  (GLY372)   [view usage] : d.87.1.1 |CO dehydrogenase flavoprotein C-domain-like |FAD/NAD-linked reductases, dimerisation (C-terminal) domain |FAD/NAD-linked reductases, dimerisation (C-terminal) domain |Dihydrolipoamide dehydrogenase |Bacillus stearothermophilus [TaxId: 1422]
 d1ki9a_ :    (SER93)  (LEU113)   [view usage] : c.37.1.1 |P-loop containing nucleoside triphosphate hydrolases |P-loop containing nucleoside triphosphate hydrolases |Nucleotide and nucleoside kinases |Adenylate kinase |Methanococcus thermolithotrophicus [TaxId: 2186]

List of distinct SCOP folds where this concept is used (in one or more of its domains):
  b.80,     c.1,    b.19,    c.69,   d.159,    d.58,     i.1,    b.47,    c.45,   a.127,   d.144,    b.40,    c.37,   d.104,    c.55,     d.2,    c.95,    b.60,    d.14,   b.121,  
d.81, d.20, c.43, d.87, b.34, d.145, a.138, b.17, c.119, c.103, g.76, d.189, g.90, d.154