Protein Concepts Dictionary

Tableau information

Concept source:  d1ak4a_  amino acid (a.a.) range (VAL2)(PRO30)

nSSEs in this Concept: 3

String of secondary struct.elems. (SSEs) defining this concept: EEH

Each SSE's a.a.range: (start resi) (end resi) SSEtype (H=Helix; E=Strand) followed by a numeric SSE ID:
	    (VAL2)   (VAL12) E1
	   (GLY18)   (GLU23) E2
	   (PHE25)   (PRO30) H3

Orientation angles° of SSE-pairs; those in contact shown in bold font
          E1                   
E2      162.0°   E2            
H3      101.4°  -63.7°       
Footnote: Inferred from this concept's usages (listed below) was the angular variance of 1σ = ±5.9°  about each orientation angle shown above.

Loci of concept usages (shown as a range of a.a. residue ids) in SCOP(v2.05) domains, along with their brief legend taken from SCOP
 d1t3ca_ :   (GLU188)  (GLY222)   [view usage] : d.92.1.7 |Zincin-like |Metalloproteases ("zincins"), catalytic domain |Clostridium neurotoxins, catalytic domain |Botulinum neurotoxin |Clostridium botulinum, serotype E [TaxId: 1491]
 d1dypa_ :   (ARG176)  (HIS205)   [view usage] : b.29.1.2 |Concanavalin A-like lectins/glucanases |Concanavalin A-like lectins/glucanases |Glycosyl hydrolases family 16 |kappa-Carrageenase, catalytic |Pseudoalteromonas carrageenovora [TaxId: 227]
 d1uasa1 :   (ASN297)  (GLY321)   [view usage] : b.71.1.1 |Glycosyl hydrolase domain |Glycosyl hydrolase domain |alpha-Amylases, C-terminal beta-sheet domain |Melibiase |Rice (Oryza sativa) [TaxId: 4530]
 d2wlwa_ :     (PRO4)   (PRO30)   [view usage] : b.62.1.1 |Cyclophilin-like |Cyclophilin-like |Cyclophilin (peptidylprolyl isomerase) |automated matches |Rhesus monkey (Macaca mulatta) [TaxId: 9544]
 d3nidc_ :   (TYR237)  (TRP260)   [view usage] : b.69.8.1 |7-bladed beta-propeller |Integrin alpha N-terminal domain |Integrin alpha N-terminal domain |Integrin alpha N-terminal domain |Human (Homo sapiens), isoform IIb [TaxId: 9606]
 d1zzoa1 :    (GLN51)   (LYS70)   [view usage] : c.47.1.10 |Thioredoxin fold |Thioredoxin-like |Glutathione peroxidase-like |Lipoprotein DsbF |Mycobacterium tuberculosis [TaxId: 1773]
 d3c9xa_ :   (SER256)  (ASN274)   [view usage] : b.50.1.0 |Acid proteases |Acid proteases |automated matches |automated matches |Trichoderma reesei [TaxId: 51453]
 d4hx2d_ :     (GLY4)   (THR52)   [view usage] : d.84.1.0 |Subtilisin inhibitor |Subtilisin inhibitor |automated matches |automated matches |Streptomyces caespitosus [TaxId: 53502]
 d3or1c_ :     (ALA2)   (GLY38)   [view usage] : d.203.1.1 |DsrC, the gamma subunit of dissimilatory sulfite reductase |DsrC, the gamma subunit of dissimilatory sulfite reductase |DsrC, the gamma subunit of dissimilatory sulfite reductase |automated matches |Desulfovibrio gigas [TaxId: 879]
 d3or2c_ :     (ALA2)   (GLY38)   [view usage] : d.203.1.1 |DsrC, the gamma subunit of dissimilatory sulfite reductase |DsrC, the gamma subunit of dissimilatory sulfite reductase |DsrC, the gamma subunit of dissimilatory sulfite reductase |automated matches |Desulfovibrio gigas [TaxId: 879]
 d1q5qh_ :   (PRO192)  (GLU223)   [view usage] : d.153.1.4 |Ntn hydrolase-like |N-terminal nucleophile aminohydrolases (Ntn hydrolases) |Proteasome subunits |Proteasome beta subunit (catalytic) |Rhodococcus erythropolis [TaxId: 1833]
 d4kypa_ :    (GLU38)   (GLN72)   [view usage] : g.3.7.1 |Knottins (small inhibitors, toxins, lectins) |Scorpion toxin-like |Long-chain scorpion toxins |automated matches |Hottentotta judaicus [TaxId: 6863]
 d2vc2a_ :   (TYR237)  (TRP260)   [view usage] : b.69.8.1 |7-bladed beta-propeller |Integrin alpha N-terminal domain |Integrin alpha N-terminal domain |Integrin alpha N-terminal domain |Human (Homo sapiens), isoform IIb [TaxId: 9606]
 d1vjfa_ :    (HIS43)   (GLY94)   [view usage] : d.116.1.1 |YbaK/ProRS associated domain |YbaK/ProRS associated domain |YbaK/ProRS associated domain |Hypothetical protein CC0111 |Caulobacter crescentus [TaxId: 155892]
 d1q8ka4 :    (MET29)   (ARG52)   [view usage] : b.40.4.5 |OB-fold |Nucleic acid-binding proteins |Cold shock DNA-binding domain-like |Eukaryotic initiation factor 2alpha, eIF2alpha, N-terminal domain |Human (Homo sapiens) [TaxId: 9606]
 d2r7da2 :   (LEU240)  (GLU285)   [view usage] : b.40.4.16 |OB-fold |Nucleic acid-binding proteins |RNB domain-like |Ribonuclease II family protein DR0020 |Deinococcus radiodurans [TaxId: 1299]
 d1stma_ :    (ALA17)   (PRO45)   [view usage] : b.121.7.1 |Nucleoplasmin-like/VP (viral coat and capsid proteins) |Satellite viruses |Satellite viruses |SPMV coat protein |Satellite panicum mosaic virus [TaxId: 154834]
 d1ya7a_ :   (GLU211)  (LEU233)   [view usage] : d.153.1.4 |Ntn hydrolase-like |N-terminal nucleophile aminohydrolases (Ntn hydrolases) |Proteasome subunits |automated matches |Thermoplasma acidophilum [TaxId: 2303]
 d3zboa_ :   (GLY197)  (GLY224)   [view usage] : a.118.1.17 |alpha-alpha superhelix |ARM repeat |BC3264-like |automated matches |Bacillus cereus [TaxId: 1396]
 d1duwa_ :    (SER12)   (ILE44)   [view usage] : a.138.1.1 |Multiheme cytochromes |Multiheme cytochromes |Cytochrome c3-like |Nine-heme cytochrome c |Desulfovibrio desulfuricans, ATCC 29577 [TaxId: 876]
 d1od2a2 :  (THR1898) (GLN1944)   [view usage] : c.14.1.4 |ClpP/crotonase |ClpP/crotonase |Biotin dependent carboxylase carboxyltransferase domain |Acetyl-coenzyme A carboxylase |Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]
 d1z7qh1 :   (ILE173)  (LEU196)   [view usage] : d.153.1.4 |Ntn hydrolase-like |N-terminal nucleophile aminohydrolases (Ntn hydrolases) |Proteasome subunits |Proteasome beta subunit (catalytic) |Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]
 d3fcca_ :    (ALA19)   (PRO48)   [view usage] : e.23.1.0 |Acetyl-CoA synthetase-like |Acetyl-CoA synthetase-like |automated matches |automated matches |Bacillus cereus [TaxId: 226900]
 d3fcca_ :   (TYR148)  (GLU178)   [view usage] : e.23.1.0 |Acetyl-CoA synthetase-like |Acetyl-CoA synthetase-like |automated matches |automated matches |Bacillus cereus [TaxId: 226900]
 d4a2ba2 :   (GLU274)  (GLU322)   [view usage] : c.55.1.1 |Ribonuclease H-like motif |Actin-like ATPase domain |Actin/HSP70 |Cell division protein FtsA |Thermotoga maritima [TaxId: 2336]
 d2gjua_ :   (ILE123)  (GLY147)   [view usage] : d.159.1.5 |Metallo-dependent phosphatases |Metallo-dependent phosphatases |Phosphoesterase-related |automated matches |Pyrococcus horikoshii [TaxId: 70601]
 d1f36a_ :    (VAL13)   (GLN41)   [view usage] : a.4.1.12 |DNA/RNA-binding 3-helical bundle |Homeodomain-like |FIS-like |FIS protein |Escherichia coli [TaxId: 562]
 d1pixa3 :   (GLY366)  (ASP404)   [view usage] : c.14.1.4 |ClpP/crotonase |ClpP/crotonase |Biotin dependent carboxylase carboxyltransferase domain |Glutaconyl-CoA decarboxylase A subunit |Acidaminococcus fermentans [TaxId: 905]
 d1xxea1 :    (THR60)   (LEU82)   [view usage] : d.14.1.7 |Ribosomal protein S5 domain 2-like |Ribosomal protein S5 domain 2-like |UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase LpxC |UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase LpxC |Aquifex aeolicus [TaxId: 63363]
 d1tyea_ :   (TYR237)  (TRP260)   [view usage] : b.69.8.1 |7-bladed beta-propeller |Integrin alpha N-terminal domain |Integrin alpha N-terminal domain |Integrin alpha N-terminal domain |Human (Homo sapiens), isoform IIb [TaxId: 9606]
 d1bcga_ :    (GLU38)   (CYS69)   [view usage] : g.3.7.1 |Knottins (small inhibitors, toxins, lectins) |Scorpion toxin-like |Long-chain scorpion toxins |Scorpion toxin |Scorpion (Buthotus judaicus), BJXTR-IT [TaxId: 6863]
 d1ng9a1 :   (ARG492)  (LEU535)   [view usage] : a.113.1.1 |DNA repair protein MutS, domain III |DNA repair protein MutS, domain III |DNA repair protein MutS, domain III |DNA repair protein MutS, domain III |Escherichia coli [TaxId: 562]
 d3selx_ :     (ASP3)   (ALA23)   [view usage] : a.138.1.1 |Multiheme cytochromes |Multiheme cytochromes |Cytochrome c3-like |automated matches |Geobacter sulfurreducens [TaxId: 35554]
 d3mi0r_ :   (PRO492)  (GLY528)   [view usage] : d.153.1.4 |Ntn hydrolase-like |N-terminal nucleophile aminohydrolases (Ntn hydrolases) |Proteasome subunits |automated matches |Mycobacterium tuberculosis [TaxId: 1773]
 d2v4jc1 :     (GLU3)   (VAL33)   [view usage] : d.203.1.1 |DsrC, the gamma subunit of dissimilatory sulfite reductase |DsrC, the gamma subunit of dissimilatory sulfite reductase |DsrC, the gamma subunit of dissimilatory sulfite reductase |DsrC, the gamma subunit of dissimilatory sulfite reductase |Desulfovibrio vulgaris [TaxId: 881]
 d1zn3a_ :   (GLU188)  (HIS211)   [view usage] : d.92.1.7 |Zincin-like |Metalloproteases ("zincins"), catalytic domain |Clostridium neurotoxins, catalytic domain |automated matches |Clostridium botulinum [TaxId: 1491]
 d2ku2a_ :   (GLU211)  (LYS231)   [view usage] : d.153.1.4 |Ntn hydrolase-like |N-terminal nucleophile aminohydrolases (Ntn hydrolases) |Proteasome subunits |automated matches |Thermoplasma acidophilum [TaxId: 2303]
 d2yoaa_ :   (LYS354)  (ALA395)   [view usage] : b.7.1.2 |C2 domain-like |C2 domain (Calcium/lipid-binding domain, CaLB) |Synaptotagmin-like (S variant) |automated matches |Norway rat (Rattus norvegicus) [TaxId: 10116]
 d1nm3a2 :    (GLN11)   (PHE31)   [view usage] : c.47.1.10 |Thioredoxin fold |Thioredoxin-like |Glutathione peroxidase-like |N-terminal, Prx domain of Hybrid-Prx5 |Haemophilus influenzae [TaxId: 727]
 d2oa4a1 :    (ARG11)   (VAL43)   [view usage] : a.4.12.3 |DNA/RNA-binding 3-helical bundle |TrpR-like |SPO1678-like |Uncharacterized protein SPO1678 |Silicibacter pomeroyi [TaxId: 89184]
 d1pmaa_ :   (GLU211)  (LYS231)   [view usage] : d.153.1.4 |Ntn hydrolase-like |N-terminal nucleophile aminohydrolases (Ntn hydrolases) |Proteasome subunits |Proteasome alpha subunit (non-catalytic) |Thermoplasma acidophilum [TaxId: 2303]
 d3ilwb_ :   (GLY225)  (GLY247)   [view usage] : e.11.1.0 |Type II DNA topoisomerase C-terminal domain-like |Type II DNA topoisomerase C-terminal domain-like |automated matches |automated matches |Mycobacterium tuberculosis [TaxId: 1773]
 d1yx3a_ :     (MET1)   (ASN39)   [view usage] : d.203.1.1 |DsrC, the gamma subunit of dissimilatory sulfite reductase |DsrC, the gamma subunit of dissimilatory sulfite reductase |DsrC, the gamma subunit of dissimilatory sulfite reductase |DsrC, the gamma subunit of dissimilatory sulfite reductase |Allochromatium vinosum [TaxId: 1049]
 d4foaa_ :    (ARG99)  (ARG120)   [view usage] : d.117.1.1 |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase/dCMP hydroxymethylase |automated matches |Mycobacterium tuberculosis [TaxId: 1773]
 d4dnza_ :   (PHE298)  (ASP329)   [view usage] : a.104.1.0 |Cytochrome P450 |Cytochrome P450 |automated matches |automated matches |Rhodopseudomonas palustris [TaxId: 316058]
 d1hxma1 :    (TYR34)   (ASN63)   [view usage] : b.1.1.1 |Immunoglobulin-like beta-sandwich |Immunoglobulin |V set domains (antibody variable domain-like) |T-cell antigen receptor |Human (Homo sapiens), gamma-chain [TaxId: 9606]
 d2alfa1 :     (VAL2)   (PRO30)   [view usage] : b.62.1.1 |Cyclophilin-like |Cyclophilin-like |Cyclophilin (peptidylprolyl isomerase) |Cyclophilin (eukaryotic) |Human (Homo sapiens), variant A [TaxId: 9606]
 d3ifzb_ :   (GLY225)  (GLY247)   [view usage] : e.11.1.0 |Type II DNA topoisomerase C-terminal domain-like |Type II DNA topoisomerase C-terminal domain-like |automated matches |automated matches |Mycobacterium tuberculosis [TaxId: 83332]
 d4nnnc_ :   (GLU209)  (GLN239)   [view usage] : d.153.1.4 |Ntn hydrolase-like |N-terminal nucleophile aminohydrolases (Ntn hydrolases) |Proteasome subunits |automated matches |Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]
 d1a76a2 :   (PRO182)  (ARG208)   [view usage] : c.120.1.2 |PIN domain-like |PIN domain-like |5' to 3' exonuclease catalytic domain |Flap endonuclease-1 (Fen-1 nuclease) |Methanococcus jannaschii [TaxId: 2190]
 d3k0ra_ :     (ASN3)   (PRO30)   [view usage] : b.62.1.1 |Cyclophilin-like |Cyclophilin-like |Cyclophilin (peptidylprolyl isomerase) |Cyclophilin (eukaryotic) |Human (Homo sapiens), variant A [TaxId: 9606]
 d1smja_ :   (PRO329)  (ASP363)   [view usage] : a.104.1.1 |Cytochrome P450 |Cytochrome P450 |Cytochrome P450 |Cytochrome P450 bm-3 |Bacillus megaterium [TaxId: 1404]
 d1c20a_ :    (ARG45)   (GLY67)   [view usage] : a.4.3.1 |DNA/RNA-binding 3-helical bundle |ARID-like |ARID domain |DNA-binding domain from the dead ringer protein |Fruit fly (Drosophila melanogaster) [TaxId: 7227]
 d1mc8a2 :   (PRO182)  (LYS220)   [view usage] : c.120.1.2 |PIN domain-like |PIN domain-like |5' to 3' exonuclease catalytic domain |Flap endonuclease-1 (Fen-1 nuclease) |Pyrococcus horikoshii [TaxId: 53953]
 d3t6dc_ :     (THR8)   (PRO39)   [view usage] : a.138.1.2 |Multiheme cytochromes |Multiheme cytochromes |Photosynthetic reaction centre (cytochrome subunit) |automated matches |Blastochloris viridis [TaxId: 1079]
 d2hrfa_ :   (PHE140)  (GLN158)   [view usage] : c.47.1.0 |Thioredoxin fold |Thioredoxin-like |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1irax_ :    (LYS64)   (PHE98)   [view usage] : b.42.1.2 |beta-Trefoil |Cytokine |Interleukin-1 (IL-1) |Interleukin-1 receptor antagonist protein |Human (Homo sapiens) [TaxId: 9606]
 d3s0ma_ :   (PHE226)  (LYS252)   [view usage] : b.82.1.2 |Double-stranded beta-helix |RmlC-like cupins |Germin/Seed storage 7S protein |Oxalate decarboxylase OxdC (YvrK) |Bacillus subtilis [TaxId: 1423]
 d2xsjc_ :     (ALA2)   (GLY38)   [view usage] : d.203.1.1 |DsrC, the gamma subunit of dissimilatory sulfite reductase |DsrC, the gamma subunit of dissimilatory sulfite reductase |DsrC, the gamma subunit of dissimilatory sulfite reductase |automated matches |Desulfomicrobium norvegicum [TaxId: 52561]
 d4wz8c2 :  (THR1898) (GLN1944)   [view usage] : c.14.1.4 |ClpP/crotonase |ClpP/crotonase |Biotin dependent carboxylase carboxyltransferase domain |automated matches |Baker's yeast (Saccharomyces cerevisiae) [TaxId: 559292]
 d1vava_ :     (THR6)   (ARG27)   [view usage] : b.29.1.18 |Concanavalin A-like lectins/glucanases |Concanavalin A-like lectins/glucanases |Alginate lyase |Alginate lyase PA1167 |Pseudomonas aeruginosa [TaxId: 287]
 d3ssia_ :     (ALA8)   (GLY57)   [view usage] : d.84.1.1 |Subtilisin inhibitor |Subtilisin inhibitor |Subtilisin inhibitor |Subtilisin inhibitor |Streptomyces albogriseolus, s-3253 [TaxId: 1887]
 d3k0na_ :     (PRO4)   (PRO30)   [view usage] : b.62.1.1 |Cyclophilin-like |Cyclophilin-like |Cyclophilin (peptidylprolyl isomerase) |Cyclophilin (eukaryotic) |Human (Homo sapiens), variant A [TaxId: 9606]
 d4gvqa_ :    (ARG23)   (VAL42)   [view usage] : d.147.1.0 |Methenyltetrahydromethanopterin cyclohydrolase |Methenyltetrahydromethanopterin cyclohydrolase |automated matches |automated matches |Archaeoglobus fulgidus [TaxId: 224325]
 d2b5la1 :   (GLU235)  (SER256)   [view usage] : b.69.4.3 |7-bladed beta-propeller |WD40 repeat-like |DDB1-like |DDB1 |Human (Homo sapiens) [TaxId: 9606]
 d3hfav_ :   (PRO492)  (GLY523)   [view usage] : d.153.1.4 |Ntn hydrolase-like |N-terminal nucleophile aminohydrolases (Ntn hydrolases) |Proteasome subunits |automated matches |Mycobacterium tuberculosis [TaxId: 1773]
 d1ak4a_ :     (VAL2)   (PRO30)   [view usage] : b.62.1.1 |Cyclophilin-like |Cyclophilin-like |Cyclophilin (peptidylprolyl isomerase) |Cyclophilin (eukaryotic) |Human (Homo sapiens), variant A [TaxId: 9606]
 d2o3ba1 :    (ASP95)  (SER118)   [view usage] : d.4.1.2 |His-Me finger endonucleases |His-Me finger endonucleases |DNA/RNA non-specific endonuclease |Nuclease NucA |Nostoc sp. PCC 7120 [TaxId: 103690]
 d2ku1a_ :   (GLU211)  (LYS231)   [view usage] : d.153.1.4 |Ntn hydrolase-like |N-terminal nucleophile aminohydrolases (Ntn hydrolases) |Proteasome subunits |automated matches |Thermoplasma acidophilum [TaxId: 2303]
 d1ryph_ :   (ILE173)  (LEU196)   [view usage] : d.153.1.4 |Ntn hydrolase-like |N-terminal nucleophile aminohydrolases (Ntn hydrolases) |Proteasome subunits |Proteasome beta subunit (catalytic) |Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]
 d3krdr_ :   (PRO492)  (GLY528)   [view usage] : d.153.1.4 |Ntn hydrolase-like |N-terminal nucleophile aminohydrolases (Ntn hydrolases) |Proteasome subunits |automated matches |Mycobacterium tuberculosis [TaxId: 1773]
 d1nnwa_ :   (ILE123)  (GLY147)   [view usage] : d.159.1.5 |Metallo-dependent phosphatases |Metallo-dependent phosphatases |Phosphoesterase-related |Hypothetical protein PF1291 |Pyrococcus furiosus [TaxId: 2261]
 d1nnwb_ :   (ILE123)  (GLY147)   [view usage] : d.159.1.5 |Metallo-dependent phosphatases |Metallo-dependent phosphatases |Phosphoesterase-related |Hypothetical protein PF1291 |Pyrococcus furiosus [TaxId: 2261]
 d2rs4a_ :     (MET1)   (PRO21)   [view usage] : b.62.1.1 |Cyclophilin-like |Cyclophilin-like |Cyclophilin (peptidylprolyl isomerase) |Peptidyl-prolyl cis-trans isomerase A, PpiA |Escherichia coli [TaxId: 562]
 d1vsyd_ :  (ILE4212) (GLU4242)   [view usage] : d.153.1.4 |Ntn hydrolase-like |N-terminal nucleophile aminohydrolases (Ntn hydrolases) |Proteasome subunits |automated matches |Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]
 d1vjca_ :   (GLY129)  (LYS155)   [view usage] : c.86.1.1 |Phosphoglycerate kinase |Phosphoglycerate kinase |Phosphoglycerate kinase |Phosphoglycerate kinase |Pig (Sus scrofa) [TaxId: 9823]

List of distinct SCOP folds where this concept is used (in one or more of its domains):
  b.82,   a.104,   d.159,    b.69,   a.118,    b.29,   d.117,    d.92,    c.14,    b.50,    b.40,    c.47,    c.55,    c.86,   d.153,    d.14,   b.121,     b.1,    e.23,    e.11,  
d.116, b.42, b.62, c.120, a.4, a.138, b.7, b.71, d.4, a.113, g.3, d.203, d.147, d.84