Protein Concepts Dictionary

Tableau information

Concept source:  d1jjua4  amino acid (a.a.) range (LEU435)(THR479)

nSSEs in this Concept: 3

String of secondary struct.elems. (SSEs) defining this concept: EEE

Each SSE's a.a.range: (start resi) (end resi) SSEtype (H=Helix; E=Strand) followed by a numeric SSE ID:
	  (LEU435)  (ALA439) E1
	  (LYS458)  (ASP464) E2
	  (PRO469)  (THR479) E3

Orientation angles° of SSE-pairs; those in contact shown in bold font
          E1                   
E2      149.5°   E2            
E3      -37.3°  151.6°       
Footnote: Inferred from this concept's usages (listed below) was the angular variance of 1σ = ±9.9°  about each orientation angle shown above.

Loci of concept usages (shown as a range of a.a. residue ids) in SCOP(v2.05) domains, along with their brief legend taken from SCOP
 d3eiya_ :    (PHE16)   (ARG44)   [view usage] : b.40.5.1 |OB-fold |Inorganic pyrophosphatase |Inorganic pyrophosphatase |automated matches |Burkholderia pseudomallei [TaxId: 320372]
 d2ovpb2 :  (LYS2374) (SER2398)   [view usage] : b.69.4.1 |7-bladed beta-propeller |WD40 repeat-like |WD40-repeat |F-box/WD repeat-containing protein 7, FBXW7 |Human (Homo sapiens) [TaxId: 9606]
 d4g9ja_ :   (ASP242)  (ALA269)   [view usage] : d.159.1.3 |Metallo-dependent phosphatases |Metallo-dependent phosphatases |Protein serine/threonine phosphatase |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1l3wa4 :   (GLY392)  (VAL430)   [view usage] : b.1.6.1 |Immunoglobulin-like beta-sandwich |Cadherin-like |Cadherin |C-cadherin ectodomain |African clawed frog (Xenopus laevis) [TaxId: 8355]
 d2v64h_ :   (SER148)  (LYS192)   [view usage] : d.135.1.1 |The spindle assembly checkpoint protein mad2 |The spindle assembly checkpoint protein mad2 |The spindle assembly checkpoint protein mad2 |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d3sika_ :   (ASN108)  (ASP147)   [view usage] : b.1.28.0 |Immunoglobulin-like beta-sandwich |NEAT domain-like |automated matches |automated matches |Anthrax bacillus (Bacillus anthracis) [TaxId: 1392]
 d1ds6b_ :   (VAL159)  (ILE195)   [view usage] : b.1.18.8 |Immunoglobulin-like beta-sandwich |E set domains |RhoGDI-like |Rho GDP-dissociation inhibitor 1, RhoGDI |Human (Homo sapiens) [TaxId: 9606]
 d1d7pm_ :  (VAL2293) (GLY2325)   [view usage] : b.18.1.2 |Galactose-binding domain-like |Galactose-binding domain-like |Discoidin domain (FA58C, coagulation factor 5/8 C-terminal domain) |C2 domain of factor VIII |Human (Homo sapiens) [TaxId: 9606]
 d4c2bb_ :   (TYR185)  (ASN210)   [view usage] : c.10.2.7 |Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) |L domain-like |Ngr ectodomain-like |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d2h6ca2 :    (SER82)  (SER108)   [view usage] : b.82.3.2 |Double-stranded beta-helix |cAMP-binding domain-like |cAMP-binding domain |Chlorophenol reduction protein CprK |Desulfitobacterium dehalogenans [TaxId: 36854]
 d2vmja1 :   (GLY111)  (PRO144)   [view usage] : b.6.1.3 |Cupredoxin-like |Cupredoxins |Multidomain cupredoxins |automated matches |Alcaligenes xylosoxydans [TaxId: 85698]
 d1doab_ :   (MET162)  (LYS200)   [view usage] : b.1.18.8 |Immunoglobulin-like beta-sandwich |E set domains |RhoGDI-like |Rho GDP-dissociation inhibitor 1, RhoGDI |Cow (Bos taurus) [TaxId: 9913]
 d1vybb_ :   (ASP205)  (ARG238)   [view usage] : d.151.1.1 |DNase I-like |DNase I-like |DNase I-like |Endonuclease domain of LINE-1 reverse transcriptase homolog |Human (Homo sapiens) [TaxId: 9606]
 d1tnra_ :   (GLU127)  (ALA170)   [view usage] : b.22.1.1 |TNF-like |TNF-like |TNF-like |Tumor necrosis factor (TNF) |Human (Homo sapiens) [TaxId: 9606]
 d1crla_ :    (THR99)  (SER131)   [view usage] : c.69.1.17 |alpha/beta-Hydrolases |alpha/beta-Hydrolases |Fungal lipases |Type-B carboxylesterase/lipase |Fungus (Candida rugosa), formerly Cylindracea [TaxId: 5481]
 d2azua_ :    (GLU91)  (LEU127)   [view usage] : b.6.1.1 |Cupredoxin-like |Cupredoxins |Plastocyanin/azurin-like |Azurin |Pseudomonas aeruginosa [TaxId: 287]
 d1akna_ :    (LEU81)  (GLN115)   [view usage] : c.69.1.1 |alpha/beta-Hydrolases |alpha/beta-Hydrolases |Acetylcholinesterase-like |Bile-salt activated lipase (cholesterol esterase) |Cow (Bos taurus) [TaxId: 9913]
 d1iqaa_ :   (GLU268)  (LYS311)   [view usage] : b.22.1.1 |TNF-like |TNF-like |TNF-like |TRANCE/RANKL cytokine |Mouse (Mus musculus) [TaxId: 10090]
 d2wq8a1 :   (THR111)  (ALA148)   [view usage] : b.18.1.0 |Galactose-binding domain-like |Galactose-binding domain-like |automated matches |automated matches |Fusarium graminearum (Gibberella zeae) [TaxId: 5518]
 d1r61a_ :   (GLY168)  (ASP202)   [view usage] : c.8.8.1 |The "swivelling" beta/beta/alpha domain |Putative cyclase |Putative cyclase |Unnamed protein |Bacillus stearothermophilus [TaxId: 1422]
 d1dlca1 :   (THR611)  (PRO642)   [view usage] : b.18.1.3 |Galactose-binding domain-like |Galactose-binding domain-like |delta-Endotoxin, C-terminal domain |delta-Endotoxin, C-terminal domain |Bacillus thuringiensis tenebrionis, CRYIIIA (BT13) [TaxId: 1444]
 d1wh0a_ :    (THR78)  (ARG110)   [view usage] : b.15.1.3 |HSP20-like chaperones |HSP20-like chaperones |GS domain |Ubiquitin carboxyl-terminal hydrolase 19, USP19 |Human (Homo sapiens) [TaxId: 9606]
 d2dp9a_ :    (ARG29)   (VAL53)   [view usage] : b.122.1.5 |PUA domain-like |PUA domain-like |Hypothetical protein TTHA0113 |automated matches |Thermus thermophilus HB8 [TaxId: 300852]
 d1dlca2 :   (SER449)  (HIS495)   [view usage] : b.77.2.1 |beta-Prism I |delta-Endotoxin (insectocide), middle domain |delta-Endotoxin (insectocide), middle domain |delta-Endotoxin (insectocide), middle domain |Bacillus thuringiensis tenebrionis, CRYIIIA (BT13) [TaxId: 1444]
 d2abja_ :    (ILE29)   (ILE71)   [view usage] : e.17.1.1 |D-aminoacid aminotransferase-like PLP-dependent enzymes |D-aminoacid aminotransferase-like PLP-dependent enzymes |D-aminoacid aminotransferase-like PLP-dependent enzymes |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1vyba_ :   (ASP205)  (ARG238)   [view usage] : d.151.1.1 |DNase I-like |DNase I-like |DNase I-like |Endonuclease domain of LINE-1 reverse transcriptase homolog |Human (Homo sapiens) [TaxId: 9606]
 d4arxa3 :   (ALA576)  (VAL608)   [view usage] : b.18.1.0 |Galactose-binding domain-like |Galactose-binding domain-like |automated matches |automated matches |Bacillus thuringiensis [TaxId: 29339]
 d4c2la_ :   (ASP340)  (GLY375)   [view usage] : b.80.1.0 |Single-stranded right-handed beta-helix |Pectin lyase-like |automated matches |automated matches |Aspergillus tubingensis [TaxId: 5068]
 d4e4dx_ :   (GLU268)  (LYS311)   [view usage] : b.22.1.1 |TNF-like |TNF-like |TNF-like |TRANCE/RANKL cytokine |Mouse (Mus musculus) [TaxId: 10090]
 d1oq1b_ :    (HIS47)   (ALA80)   [view usage] : b.29.1.17 |Concanavalin A-like lectins/glucanases |Concanavalin A-like lectins/glucanases |Hypothetical protein YesU |Hypothetical protein YesU |Bacillus subtilis [TaxId: 1423]
 d1vysx_ :   (GLN117)  (GLU152)   [view usage] : c.1.4.1 |TIM beta/alpha-barrel |FMN-linked oxidoreductases |FMN-linked oxidoreductases |Pentaerythritol tetranirate reductase |Enterobacter cloacae [TaxId: 550]
 d1k25a2 :   (GLU717)  (THR747)   [view usage] : d.11.1.1 |Penicillin-binding protein 2x (pbp-2x), c-terminal domain |Penicillin-binding protein 2x (pbp-2x), c-terminal domain |Penicillin-binding protein 2x (pbp-2x), c-terminal domain |Penicillin-binding protein 2x (pbp-2x), c-terminal domain |Pneumococcus (Streptococcus pneumoniae) [TaxId: 1313]
 d3ppea1 :    (ASP54)   (ILE97)   [view usage] : b.1.6.0 |Immunoglobulin-like beta-sandwich |Cadherin-like |automated matches |automated matches |Chicken (Gallus gallus) [TaxId: 9031]
 d1mx1b_ :  (LEU2119) (SER2150)   [view usage] : c.69.1.1 |alpha/beta-Hydrolases |alpha/beta-Hydrolases |Acetylcholinesterase-like |Mammalian carboxylesterase (liver carboxylesterase I) |Human (Homo sapiens) [TaxId: 9606]
 d2aepa1 :   (PHE100)  (LEU134)   [view usage] : b.68.1.1 |6-bladed beta-propeller |Sialidases |Sialidases (neuraminidases) |Influenza neuraminidase |Influenza A virus, different strains [TaxId: 11320]
 d1hh4e_ :   (VAL462)  (ILE498)   [view usage] : b.1.18.8 |Immunoglobulin-like beta-sandwich |E set domains |RhoGDI-like |Rho GDP-dissociation inhibitor 1, RhoGDI |Human (Homo sapiens) [TaxId: 9606]
 d4qjeb_ :     (GLN9)   (THR44)   [view usage] : c.82.1.0 |ALDH-like |ALDH-like |automated matches |automated matches |Staphylococcus aureus [TaxId: 93062]
 d2hdka_ :    (GLN11)   (ILE53)   [view usage] : e.17.1.1 |D-aminoacid aminotransferase-like PLP-dependent enzymes |D-aminoacid aminotransferase-like PLP-dependent enzymes |D-aminoacid aminotransferase-like PLP-dependent enzymes |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1rtva_ :    (GLN47)   (THR76)   [view usage] : b.82.1.1 |Double-stranded beta-helix |RmlC-like cupins |dTDP-sugar isomerase |dTDP-4-dehydrorhamnose 3,5-epimerase RmlC |Pseudomonas aeruginosa [TaxId: 287]
 d3c96a2 :   (GLY186)  (PRO220)   [view usage] : d.16.1.2 |FAD-linked reductases, C-terminal domain |FAD-linked reductases, C-terminal domain |PHBH-like |Monooxygenase PhzS |Pseudomonas aeruginosa [TaxId: 287]
 d4akda_ :   (THR119)  (LEU150)   [view usage] : b.77.3.1 |beta-Prism I |Mannose-binding lectins |Mannose-binding lectins |automated matches |Artocarpus integer [TaxId: 3490]
 d1ekfa_ :    (GLN11)   (ILE53)   [view usage] : e.17.1.1 |D-aminoacid aminotransferase-like PLP-dependent enzymes |D-aminoacid aminotransferase-like PLP-dependent enzymes |D-aminoacid aminotransferase-like PLP-dependent enzymes |Branched-chain aminoacid aminotransferase |Human (Homo sapiens), mitochondrial [TaxId: 9606]
 d2guxa1 :    (SER91)  (TYR118)   [view usage] : b.77.3.1 |beta-Prism I |Mannose-binding lectins |Mannose-binding lectins |Griffithsin |Red alga (Griffithsia) [TaxId: 35158]
 d3eb7a2 :   (GLY452)  (TRP495)   [view usage] : b.77.2.0 |beta-Prism I |delta-Endotoxin (insectocide), middle domain |automated matches |automated matches |Bacillus thuringiensis [TaxId: 1428]
 d1ugna1 :    (GLY58)   (VAL95)   [view usage] : b.1.1.4 |Immunoglobulin-like beta-sandwich |Immunoglobulin |I set domains |Ligand binding domain of lir-1 (ilt2) |Human (Homo sapiens) [TaxId: 9606]
 d4coba_ :   (GLY174)  (ALA208)   [view usage] : c.8.8.0 |The "swivelling" beta/beta/alpha domain |Putative cyclase |automated matches |automated matches |Pseudomonas aeruginosa [TaxId: 208964]
 d2ivda2 :   (PRO310)  (HIS346)   [view usage] : d.16.1.5 |FAD-linked reductases, C-terminal domain |FAD-linked reductases, C-terminal domain |L-aminoacid/polyamine oxidase |Protoporphyrinogen oxidase |Myxococcus xanthus [TaxId: 34]
 d2dypd1 :    (GLY58)   (MET94)   [view usage] : b.1.1.4 |Immunoglobulin-like beta-sandwich |Immunoglobulin |I set domains |Ligand binding domain of lir-2 (ilt4) |Human (Homo sapiens) [TaxId: 9606]
 d1gw6a3 :   (TYR256)  (THR279)   [view usage] : d.92.1.13 |Zincin-like |Metalloproteases ("zincins"), catalytic domain |Zn aminopeptidase catalytic domain |Leukotriene A4 hydrolase catalytic domain |Human (Homo sapiens) [TaxId: 9606]
 d4neaa1 :     (GLN9)   (THR44)   [view usage] : c.82.1.0 |ALDH-like |ALDH-like |automated matches |automated matches |Staphylococcus aureus [TaxId: 93062]
 d1ft0b_ :   (VAL162)  (LYS199)   [view usage] : b.1.18.8 |Immunoglobulin-like beta-sandwich |E set domains |RhoGDI-like |Rho GDP-dissociation inhibitor 1, RhoGDI |Human (Homo sapiens) [TaxId: 9606]
 d2pqsa_ :   (SER123)  (GLY157)   [view usage] : b.18.1.0 |Galactose-binding domain-like |Galactose-binding domain-like |automated matches |automated matches |Cow (Bos taurus) [TaxId: 9913]
 d3irba_ :   (TYR119)  (ASP144)   [view usage] : b.40.4.15 |OB-fold |Nucleic acid-binding proteins |SSO2064-like |Hypothetical protein SSO2064 |Sulfolobus solfataricus [TaxId: 2287]
 d3p3na_ :   (ALA198)  (PRO220)   [view usage] : b.82.2.6 |Double-stranded beta-helix |Clavaminate synthase-like |Hypoxia-inducible factor HIF ihhibitor (FIH1) |Hypoxia-inducible factor HIF ihhibitor (FIH1) |Human (Homo sapiens) [TaxId: 9606]

List of distinct SCOP folds where this concept is used (in one or more of its domains):
  b.68,    b.80,     c.1,    c.10,    b.82,    c.69,   d.159,    b.69,    b.29,    c.82,    d.92,    b.40,   d.151,    b.18,    e.17,     b.6,   b.122,     b.1,     c.8,    b.77,  
b.22, d.16, b.15, d.11, d.135