Protein Concepts Dictionary

Tableau information

Concept source:  d3ocqa_  amino acid (a.a.) range (ILE52)(HIS63)

nSSEs in this Concept: 2

String of secondary struct.elems. (SSEs) defining this concept: EH

Each SSE's a.a.range: (start resi) (end resi) SSEtype (H=Helix; E=Strand) followed by a numeric SSE ID:
	   (ILE52)   (ASN57) E1
	   (ARG58)   (HIS63) H2

Orientation angles° of SSE-pairs; those in contact shown in bold font
          E1            
H2       78.4°       
Footnote: Inferred from this concept's usages (listed below) was the angular variance of 1σ = ±4.1°  about each orientation angle shown above.

Loci of concept usages (shown as a range of a.a. residue ids) in SCOP(v2.05) domains, along with their brief legend taken from SCOP
 d1ox0a1 :     (ARG5)   (THR30)   [view usage] : c.95.1.1 |Thiolase-like |Thiolase-like |Thiolase-related |Beta-ketoacyl-ACP synthase II |Pneumococcus (Streptococcus pneumoniae) [TaxId: 1313]
 d1e5ja_ :    (GLN26)   (GLY41)   [view usage] : c.1.8.3 |TIM beta/alpha-barrel |(Trans)glycosidases |beta-glycanases |Endoglucanase Cel5a |Bacillus agaradhaerens [TaxId: 76935]
 d1q7ra_ :   (ILE101)  (ARG110)   [view usage] : c.23.16.1 |Flavodoxin-like |Class I glutamine amidotransferase-like |Class I glutamine amidotransferases (GAT) |Hypothetical protein YaaE |Bacillus stearothermophilus [TaxId: 1422]
 d3h10a_ :   (GLU269)  (HIS280)   [view usage] : d.144.1.7 |Protein kinase-like (PK-like) |Protein kinase-like (PK-like) |Protein kinases, catalytic subunit |Aurora-related kinase 1 (aurora-2) |Human (Homo sapiens) [TaxId: 9606]
 d1wy5a1 :   (VAL164)  (GLY185)   [view usage] : c.26.2.5 |Adenine nucleotide alpha hydrolase-like |Adenine nucleotide alpha hydrolases-like |PP-loop ATPase |TilS-like protein Aq_1887 |Aquifex aeolicus [TaxId: 63363]
 d1sqha_ :   (CYS152)  (ALA165)   [view usage] : d.108.1.5 |Acyl-CoA N-acyltransferases (Nat) |Acyl-CoA N-acyltransferases (Nat) |Hypothetical protein cg14615-pa |Hypothetical protein cg14615-pa |Fruit fly (Drosophila melanogaster) [TaxId: 7227]
 d3qmma_ :   (LEU124)  (ASP133)   [view usage] : c.69.1.18 |alpha/beta-Hydrolases |alpha/beta-Hydrolases |Bacterial lipase |automated matches |Bacillus subtilis [TaxId: 1423]
 d3zlfa2 :   (VAL421)  (LYS434)   [view usage] : c.1.11.0 |TIM beta/alpha-barrel |Enolase C-terminal domain-like |automated matches |automated matches |Streptococcus pyogenes [TaxId: 286636]
 d4f0ib_ :   (VAL501)  (VAL510)   [view usage] : d.144.1.0 |Protein kinase-like (PK-like) |Protein kinase-like (PK-like) |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1w0mf_ :   (HIS136)  (PRO157)   [view usage] : c.1.1.1 |TIM beta/alpha-barrel |Triosephosphate isomerase (TIM) |Triosephosphate isomerase (TIM) |Triosephosphate isomerase |Thermoproteus tenax [TaxId: 2271]
 d1hzpa2 :   (PRO176)  (ARG190)   [view usage] : c.95.1.2 |Thiolase-like |Thiolase-like |Chalcone synthase-like |Ketoacyl-ACP synthase III (FabH) |Mycobacterium tuberculosis [TaxId: 1773]
 d1q85b1 :   (PHE315)  (GLY337)   [view usage] : c.1.21.2 |TIM beta/alpha-barrel |Dihydropteroate synthetase-like |Methyltetrahydrofolate-utiluzing methyltransferases |Cobalamin-dependent methionine synthase MetH, C-terminal domain |Thermotoga maritima [TaxId: 2336]
 d1bxrb2 :   (GLU166)  (PRO191)   [view usage] : c.23.16.1 |Flavodoxin-like |Class I glutamine amidotransferase-like |Class I glutamine amidotransferases (GAT) |Carbamoyl phosphate synthetase, small subunit C-terminal domain |Escherichia coli [TaxId: 562]
 d4jrhb1 :   (VAL231)  (GLY251)   [view usage] : c.95.1.0 |Thiolase-like |Thiolase-like |automated matches |automated matches |Vibrio cholerae [TaxId: 243277]
 d1q7qa1 :   (PHE315)  (GLY337)   [view usage] : c.1.21.2 |TIM beta/alpha-barrel |Dihydropteroate synthetase-like |Methyltetrahydrofolate-utiluzing methyltransferases |Cobalamin-dependent methionine synthase MetH, C-terminal domain |Thermotoga maritima [TaxId: 2336]
 d2b1lb_ :    (MET57)   (THR66)   [view usage] : c.47.1.10 |Thioredoxin fold |Thioredoxin-like |Glutathione peroxidase-like |automated matches |Escherichia coli [TaxId: 562]
 d4amua2 :   (LYS158)  (ASN168)   [view usage] : c.78.1.0 |ATC-like |Aspartate/ornithine carbamoyltransferase |automated matches |automated matches |Mycoplasma penetrans [TaxId: 28227]
 d2qmda_ :   (PHE435)  (TYR445)   [view usage] : b.50.1.2 |Acid proteases |Acid proteases |Pepsin-like |beta-secretase (memapsin) |Human (Homo sapiens) [TaxId: 9606]
 d2hgjf1 :    (PRO94)  (GLY121)   [view usage] : c.22.1.1 |Ribosomal protein L4 |Ribosomal protein L4 |Ribosomal protein L4 |Ribosomal protein L4 |Thermus thermophilus [TaxId: 274]
 d4utua_ :   (TYR198)  (LEU220)   [view usage] : c.1.2.0 |TIM beta/alpha-barrel |Ribulose-phoshate binding barrel |automated matches |automated matches |Clostridium perfringens [TaxId: 195102]
 d3igsb_ :   (TRP202)  (ALA228)   [view usage] : c.1.2.0 |TIM beta/alpha-barrel |Ribulose-phoshate binding barrel |automated matches |automated matches |Salmonella typhimurium [TaxId: 90371]
 d1oqjb_ :   (ALA148)  (GLY163)   [view usage] : d.217.1.1 |SAND domain-like |SAND domain-like |SAND domain |Glucocorticoid modulatory element binding protein-1 (Gmeb1) |Human (Homo sapiens) [TaxId: 9606]
 d4kqxb1 :   (VAL135)  (GLY154)   [view usage] : c.2.1.0 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |automated matches |automated matches |Slackia exigua [TaxId: 649764]
 d2hr6a_ :     (ASP6)   (PRO19)   [view usage] : b.85.4.1 |beta-clip |dUTPase-like |dUTPase-like |Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) |Escherichia coli [TaxId: 562]
 d4fkba_ :    (THR74)   (HIS85)   [view usage] : c.69.1.18 |alpha/beta-Hydrolases |alpha/beta-Hydrolases |Bacterial lipase |automated matches |Bacillus sp. [TaxId: 294830]
 d1fbla1 :   (ASN346)  (GLY369)   [view usage] : b.66.1.1 |4-bladed beta-propeller |Hemopexin-like domain |Hemopexin-like domain |Collagenase (MMP1), C-terminal domain |Pig (Sus scrofa) [TaxId: 9823]
 d3peoj_ :   (ALA138)  (ILE154)   [view usage] : b.96.1.0 |Nicotinic receptor ligand binding domain-like |Nicotinic receptor ligand binding domain-like |automated matches |automated matches |California sea hare (Aplysia californica) [TaxId: 6500]
 d1khvb_ :   (GLU427)  (LYS446)   [view usage] : e.8.1.4 |DNA/RNA polymerases |DNA/RNA polymerases |RNA-dependent RNA-polymerase |Viral RNA polymerase |Rabbit hemorrhagic disease virus [TaxId: 11976]
 d1duda_ :     (ASP6)   (PHE18)   [view usage] : b.85.4.1 |beta-clip |dUTPase-like |dUTPase-like |Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) |Escherichia coli [TaxId: 562]
 d1li4a1 :   (ARG334)  (ALA350)   [view usage] : c.2.1.4 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |Formate/glycerate dehydrogenases, NAD-domain |S-adenosylhomocystein hydrolase |Human (Homo sapiens) [TaxId: 9606]
 d3clzd_ :   (THR604)  (HIS621)   [view usage] : b.122.1.12 |PUA domain-like |PUA domain-like |SRA domain-like |E3 ubiquitin-protein ligase UHRF1 |Human (Homo sapiens) [TaxId: 9606]
 d4jaoa1 :   (LEU187)  (ARG207)   [view usage] : c.95.1.0 |Thiolase-like |Thiolase-like |automated matches |automated matches |Mycobacterium tuberculosis [TaxId: 1773]
 d4k8uc_ :   (VAL309)  (LYS327)   [view usage] : b.8.1.0 |TRAF domain-like |TRAF domain-like |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d2p7le_ :   (HIS115)  (LYS129)   [view usage] : d.32.1.2 |Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase |Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase |Antibiotic resistance proteins |automated matches |Listeria monocytogenes [TaxId: 169963]
 d3ba0a2 :   (ASP350)  (GLY372)   [view usage] : b.66.1.0 |4-bladed beta-propeller |Hemopexin-like domain |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1fkna_ :    (ARG43)    (ASN5)   [view usage] : b.50.1.2 |Acid proteases |Acid proteases |Pepsin-like |beta-secretase (memapsin) |Human (Homo sapiens) [TaxId: 9606]
 d1qksa2 :   (THR554)  (THR564)   [view usage] : b.70.2.1 |8-bladed beta-propeller |C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase |C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase |C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase |Paracoccus denitrificans [TaxId: 266]
 d3h07a_ :   (ASP196)  (ARG212)   [view usage] : d.115.1.2 |YrdC/RibB |YrdC/RibB |3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB |automated matches |Yersinia pestis [TaxId: 214092]
 d1cmsa_ :   (GLU245)  (TYR255)   [view usage] : b.50.1.2 |Acid proteases |Acid proteases |Pepsin-like |Chymosin (synonym: renin) |Cow (Bos taurus) [TaxId: 9913]
 d4wh7a_ :   (LEU398)  (GLY412)   [view usage] : c.46.1.1 |Rhodanese/Cell cycle control phosphatase |Rhodanese/Cell cycle control phosphatase |Cell cycle control phosphatase, catalytic domain |CDC25b |Human (Homo sapiens) [TaxId: 9606]
 d3c1na3 :   (VAL404)  (ALA417)   [view usage] : d.58.18.0 |Ferredoxin-like |ACT-like |automated matches |automated matches |Methanocaldococcus jannaschii [TaxId: 2190]
 d1ji3a_ :    (THR74)   (HIS85)   [view usage] : c.69.1.18 |alpha/beta-Hydrolases |alpha/beta-Hydrolases |Bacterial lipase |Lipase L1 |Bacillus stearothermophilus, P1 [TaxId: 1422]
 d1wdna_ :    (GLY89)  (GLY109)   [view usage] : c.94.1.1 |Periplasmic binding protein-like II |Periplasmic binding protein-like II |Phosphate binding protein-like |Glutamine-binding protein |Escherichia coli [TaxId: 562]
 d2ifda_ :   (LEU398)  (GLY412)   [view usage] : c.46.1.1 |Rhodanese/Cell cycle control phosphatase |Rhodanese/Cell cycle control phosphatase |Cell cycle control phosphatase, catalytic domain |CDC25b |Human (Homo sapiens) [TaxId: 9606]
 d1b3na1 :   (VAL230)  (GLY250)   [view usage] : c.95.1.1 |Thiolase-like |Thiolase-like |Thiolase-related |Beta-ketoacyl-ACP synthase II |Escherichia coli [TaxId: 562]
 d1w0mg_ :   (HIS136)  (PRO157)   [view usage] : c.1.1.1 |TIM beta/alpha-barrel |Triosephosphate isomerase (TIM) |Triosephosphate isomerase (TIM) |Triosephosphate isomerase |Thermoproteus tenax [TaxId: 2271]
 d3h82a_ :   (THR255)  (ILE265)   [view usage] : d.110.3.7 |Profilin-like |PYP-like sensor domain (PAS domain) |Hypoxia-inducible factor Hif2a, C-terminal domain |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d3b2ga_ :    (CYS87)   (TYR98)   [view usage] : d.15.4.1 |beta-Grasp (ubiquitin-like) |2Fe-2S ferredoxin-like |2Fe-2S ferredoxin-related |automated matches |Leptolyngbya boryana [TaxId: 1184]
 d2wksa_ :     (MET1)   (HIS16)   [view usage] : c.23.13.1 |Flavodoxin-like |Type II 3-dehydroquinate dehydratase |Type II 3-dehydroquinate dehydratase |automated matches |Helicobacter pylori [TaxId: 210]
 d1syla_ :     (ASP6)   (PRO19)   [view usage] : b.85.4.1 |beta-clip |dUTPase-like |dUTPase-like |Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) |Escherichia coli [TaxId: 562]
 d1o6ab_ :   (THR140)  (GLU154)   [view usage] : b.139.1.1 |Surface presentation of antigens (SPOA) |Surface presentation of antigens (SPOA) |Surface presentation of antigens (SPOA) |Putative flagelar motor switch protein FliN |Thermotoga maritima [TaxId: 2336]
 d2ahva2 :   (PRO254)  (GLY271)   [view usage] : c.124.1.2 |NagB/RpiA/CoA transferase-like |NagB/RpiA/CoA transferase-like |CoA transferase alpha subunit-like |Putative enzyme YdiF N-terminal domain |Escherichia coli [TaxId: 562]
 d4ee8a_ :   (TYR288)  (LEU297)   [view usage] : d.313.1.0 |Antiparallel beta/alpha barrel (PT-barrel) |Prenyltransferase-like |automated matches |automated matches |Streptomyces cinnamonensis [TaxId: 1900]
 d3a64a_ :    (GLY18)   (GLY42)   [view usage] : c.6.1.0 |7-stranded beta/alpha barrel |Glycosyl hydrolases family 6, cellulases |automated matches |automated matches |Inky cap fungus (Coprinopsis cinerea) [TaxId: 5346]
 d3hpva2 :   (PRO281)  (ALA290)   [view usage] : d.32.1.0 |Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase |Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase |automated matches |automated matches |Pseudomonas sp. [TaxId: 237609]
 d1u6ea2 :   (PRO176)  (ARG190)   [view usage] : c.95.1.2 |Thiolase-like |Thiolase-like |Chalcone synthase-like |Ketoacyl-ACP synthase III (FabH) |Mycobacterium tuberculosis [TaxId: 1773]
 d4utta_ :   (TYR198)  (LEU220)   [view usage] : c.1.2.0 |TIM beta/alpha-barrel |Ribulose-phoshate binding barrel |automated matches |automated matches |Clostridium perfringens [TaxId: 195102]
 d4wh9a_ :   (LEU398)  (GLY412)   [view usage] : c.46.1.1 |Rhodanese/Cell cycle control phosphatase |Rhodanese/Cell cycle control phosphatase |Cell cycle control phosphatase, catalytic domain |CDC25b |Human (Homo sapiens) [TaxId: 9606]
 d1r1da_ :    (THR44)   (VAL55)   [view usage] : c.69.1.29 |alpha/beta-Hydrolases |alpha/beta-Hydrolases |Carboxylesterase/lipase |Carboxylesterase Est |Bacillus stearothermophilus [TaxId: 1422]
 d1alda_ :   (THR240)  (THR252)   [view usage] : c.1.10.1 |TIM beta/alpha-barrel |Aldolase |Class I aldolase |Fructose-1,6-bisphosphate aldolase |Human (Homo sapiens), muscle isozyme [TaxId: 9606]
 d1o7fa2 :   (LEU135)  (LYS149)   [view usage] : b.82.3.2 |Double-stranded beta-helix |cAMP-binding domain-like |cAMP-binding domain |Regulatory domain of Epac2, domains 1 and 3 |Mouse (Mus musculus) [TaxId: 10090]
 d4mfba1 :   (LYS104)  (PRO119)   [view usage] : e.8.1.2 |DNA/RNA polymerases |DNA/RNA polymerases |Reverse transcriptase |HIV-1 reverse transcriptase |Human immunodeficiency virus type 1 [TaxId: 11676]
 d1pvwa_ :   (LEU208)  (TYR220)   [view usage] : d.115.1.2 |YrdC/RibB |YrdC/RibB |3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB |3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB |Methanocaldococcus jannaschii [TaxId: 2190]
 d2oxta_ :   (ARG226)  (ARG245)   [view usage] : c.66.1.0 |S-adenosyl-L-methionine-dependent methyltransferases |S-adenosyl-L-methionine-dependent methyltransferases |automated matches |automated matches |Meaban virus [TaxId: 35279]
 d4ni2b_ :   (LYS561)  (MET573)   [view usage] : d.58.29.0 |Ferredoxin-like |Nucleotide cyclase |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d2kwba_ :   (ASN135)  (GLY147)   [view usage] : b.88.1.0 |Mss4-like |Mss4-like |automated matches |automated matches |Nematode (Caenorhabditis elegans) [TaxId: 6239]
 d3eevc_ :     (PHE8)   (VAL17)   [view usage] : b.81.1.3 |Single-stranded left-handed beta-helix |Trimeric LpxA-like enzymes |Galactoside acetyltransferase-like |automated matches |Vibrio cholerae [TaxId: 243277]
 d2zo1b_ :   (THR608)  (LYS622)   [view usage] : b.122.1.12 |PUA domain-like |PUA domain-like |SRA domain-like |E3 ubiquitin-protein ligase UHRF1 |Mouse (Mus musculus) [TaxId: 10090]
 d4c3pa_ :   (SER278)  (TYR295)   [view usage] : d.144.1.7 |Protein kinase-like (PK-like) |Protein kinase-like (PK-like) |Protein kinases, catalytic subunit |Aurora-related kinase 1 (aurora-2) |Human (Homo sapiens) [TaxId: 9606]
 d3bplb1 :    (GLY88)   (VAL96)   [view usage] : b.1.2.1 |Immunoglobulin-like beta-sandwich |Fibronectin type III |Fibronectin type III |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1hzua2 :   (THR530)  (HIS540)   [view usage] : b.70.2.1 |8-bladed beta-propeller |C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase |C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase |C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase |Pseudomonas aeruginosa [TaxId: 287]
 d1zabb_ :   (THR123)  (LEU133)   [view usage] : c.97.1.1 |Cytidine deaminase-like |Cytidine deaminase-like |Cytidine deaminase |automated matches |Mouse (Mus musculus) [TaxId: 10090]
 d1a3ha_ :    (GLN26)   (GLY41)   [view usage] : c.1.8.3 |TIM beta/alpha-barrel |(Trans)glycosidases |beta-glycanases |Endoglucanase Cel5a |Bacillus agaradhaerens [TaxId: 76935]
 d3u5ef_ :   (PRO204)  (ASN244)   [view usage] : i.1.1.1 |Ribosome and ribosomal fragments |Ribosome and ribosomal fragments |Ribosome complexes |Eukaryotic, cytoplasmic (80S ribosome functional complex) |Saccharomyces cerevisiae [TaxId: 559292]
 d3d2ba_ :   (LEU124)  (ASP133)   [view usage] : c.69.1.18 |alpha/beta-Hydrolases |alpha/beta-Hydrolases |Bacterial lipase |Lipase A |Bacillus subtilis [TaxId: 1423]
 d2gc4a_ :   (ASP258)  (GLY276)   [view usage] : b.69.2.0 |7-bladed beta-propeller |YVTN repeat-like/Quinoprotein amine dehydrogenase |automated matches |automated matches |Paracoccus denitrificans [TaxId: 318586]
 d4io4b_ :   (SER106)  (GLY126)   [view usage] : c.94.1.0 |Periplasmic binding protein-like II |Periplasmic binding protein-like II |automated matches |automated matches |Adineta vaga [TaxId: 104782]
 d1nsxb_ :   (ASN170)  (HIS186)   [view usage] : b.30.5.4 |Supersandwich |Galactose mutarotase-like |Aldose 1-epimerase (mutarotase) |Galactose mutarotase |Lactococcus lactis [TaxId: 1358]
 d1h5va_ :    (GLN26)   (GLY41)   [view usage] : c.1.8.3 |TIM beta/alpha-barrel |(Trans)glycosidases |beta-glycanases |Endoglucanase Cel5a |Bacillus agaradhaerens [TaxId: 76935]
 d2np2a_ :    (ASP87)  (ILE106)   [view usage] : a.55.1.0 |IHF-like DNA-binding proteins |IHF-like DNA-binding proteins |automated matches |automated matches |Lyme disease spirochete (Borrelia burgdorferi) [TaxId: 139]
 d2byne_ :   (ALA138)  (ILE154)   [view usage] : b.96.1.0 |Nicotinic receptor ligand binding domain-like |Nicotinic receptor ligand binding domain-like |automated matches |automated matches |California sea hare (Aplysia californica) [TaxId: 6500]
 d1jlra_ :   (ILE147)  (GLU157)   [view usage] : c.61.1.1 |PRTase-like |PRTase-like |Phosphoribosyltransferases (PRTases) |Uracil PRTase, Upp |Toxoplasma gondii [TaxId: 5811]
 d3f8jb_ :   (THR608)  (LYS622)   [view usage] : b.122.1.12 |PUA domain-like |PUA domain-like |SRA domain-like |E3 ubiquitin-protein ligase UHRF1 |Mouse (Mus musculus) [TaxId: 10090]
 d3i29b_ :    (PRO89)  (VAL116)   [view usage] : b.42.4.1 |beta-Trefoil |STI-like |Kunitz (STI) inhibitors |automated matches |Winged bean (Psophocarpus tetragonolobus) [TaxId: 3891]
 d2fr5b_ :   (THR123)  (LEU133)   [view usage] : c.97.1.1 |Cytidine deaminase-like |Cytidine deaminase-like |Cytidine deaminase |automated matches |Mouse (Mus musculus) [TaxId: 10090]
 d3pbra1 :   (ARG152)  (ALA162)   [view usage] : d.175.1.0 |Penicillin binding protein dimerisation domain |Penicillin binding protein dimerisation domain |automated matches |automated matches |Pseudomonas aeruginosa [TaxId: 208964]
 d3lf5a_ :   (VAL126)  (LYS137)   [view usage] : d.120.1.0 |Cytochrome b5-like heme/steroid binding domain |Cytochrome b5-like heme/steroid binding domain |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d2bx4a_ :   (HIS134)  (SER144)   [view usage] : b.47.1.4 |Trypsin-like serine proteases |Trypsin-like serine proteases |Viral cysteine protease of trypsin fold |Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) |Sars coronavirus sin2774 [TaxId: 235410]
 d2wifa_ :   (GLU422)  (GLY447)   [view usage] : c.69.1.1 |alpha/beta-Hydrolases |alpha/beta-Hydrolases |Acetylcholinesterase-like |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1pfda_ :    (ASP84)   (VAL96)   [view usage] : d.15.4.1 |beta-Grasp (ubiquitin-like) |2Fe-2S ferredoxin-like |2Fe-2S ferredoxin-related |2Fe-2S ferredoxin |Parsley (Petroselinum crispum) [TaxId: 4043]
 d3kpaa_ :   (GLY112)  (ASN127)   [view usage] : d.20.1.4 |UBC-like |UBC-like |UFC1-like |automated matches |Leishmania major [TaxId: 5664]
 d3gvka1 :   (VAL567)  (PRO577)   [view usage] : b.68.1.2 |6-bladed beta-propeller |Sialidases |Endo-alpha-sialidase |automated matches |Enterobacteria phage [TaxId: 344021]
 d2ycix_ :     (ILE3)   (ASN22)   [view usage] : c.1.21.2 |TIM beta/alpha-barrel |Dihydropteroate synthetase-like |Methyltetrahydrofolate-utiluzing methyltransferases |automated matches |Carboxydothermus hydrogenoformans [TaxId: 246194]
 d4kqxa1 :   (VAL135)  (GLY154)   [view usage] : c.2.1.0 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |automated matches |automated matches |Slackia exigua [TaxId: 649764]
 d1h6fa_ :   (ASP102)  (GLY120)   [view usage] : b.2.5.4 |Common fold of diphtheria toxin/transcription factors/cytochrome f |p53-like transcription factors |T-box |T-box protein 3, tbx3 |Human (Homo sapiens) [TaxId: 9606]
 d2b1la_ :    (MET57)   (THR66)   [view usage] : c.47.1.10 |Thioredoxin fold |Thioredoxin-like |Glutathione peroxidase-like |automated matches |Escherichia coli [TaxId: 562]
 d1mq0a_ :   (TYR124)  (LEU133)   [view usage] : c.97.1.1 |Cytidine deaminase-like |Cytidine deaminase-like |Cytidine deaminase |mono-domain cytidine deaminase |Human (Homo sapiens) [TaxId: 9606]
 d1yela1 :    (SER21)   (TYR31)   [view usage] : b.142.1.2 |DNA-binding pseudobarrel domain |DNA-binding pseudobarrel domain |B3 DNA binding domain |At1g16640 |Thale cress (Arabidopsis thaliana) [TaxId: 3702]
 d1ni5a1 :   (THR149)  (ASP171)   [view usage] : c.26.2.5 |Adenine nucleotide alpha hydrolase-like |Adenine nucleotide alpha hydrolases-like |PP-loop ATPase |tRNA-Ile-lysidine synthetase, TilS, N-terminal domain |Escherichia coli [TaxId: 562]
 d2fr6b_ :   (THR123)  (LEU133)   [view usage] : c.97.1.1 |Cytidine deaminase-like |Cytidine deaminase-like |Cytidine deaminase |automated matches |Mouse (Mus musculus) [TaxId: 10090]
 d1eesa_ :     (THR3)   (THR25)   [view usage] : c.37.1.8 |P-loop containing nucleoside triphosphate hydrolases |P-loop containing nucleoside triphosphate hydrolases |G proteins |CDC42 |Human (Homo sapiens) [TaxId: 9606]
 d2gfva1 :   (VAL230)  (GLY250)   [view usage] : c.95.1.1 |Thiolase-like |Thiolase-like |Thiolase-related |Beta-ketoacyl-ACP synthase II |Escherichia coli [TaxId: 562]
 d1itca2 :    (LYS12)   (THR26)   [view usage] : c.1.8.1 |TIM beta/alpha-barrel |(Trans)glycosidases |Amylase, catalytic domain |Bacterial beta-amylase |Bacillus cereus [TaxId: 1396]
 d1gnza_ :   (VAL155)  (SER167)   [view usage] : b.29.1.1 |Concanavalin A-like lectins/glucanases |Concanavalin A-like lectins/glucanases |Legume lectins |Legume lectin |Griffonia simplicifolia, lectin I-b4 [TaxId: 3850]
 d3g3bc_ :   (LEU133)  (ARG146)   [view usage] : c.10.2.0 |Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) |L domain-like |automated matches |automated matches |Sea lamprey (Petromyzon marinus) [TaxId: 7757]
 d3rodd_ :   (VAL160)  (CYS170)   [view usage] : c.66.1.0 |S-adenosyl-L-methionine-dependent methyltransferases |S-adenosyl-L-methionine-dependent methyltransferases |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d3q58a_ :   (TRP202)  (VAL224)   [view usage] : c.1.2.0 |TIM beta/alpha-barrel |Ribulose-phoshate binding barrel |automated matches |automated matches |Salmonella enterica [TaxId: 90370]
 d4r8ea1 :   (VAL230)  (GLY250)   [view usage] : c.95.1.0 |Thiolase-like |Thiolase-like |automated matches |automated matches |Yersinia pestis [TaxId: 632]
 d3hnza1 :   (VAL230)  (GLY250)   [view usage] : c.95.1.0 |Thiolase-like |Thiolase-like |automated matches |automated matches |Escherichia coli K-12 [TaxId: 83333]
 d3n8ia_ :   (LYS110)  (ASP120)   [view usage] : c.44.1.1 |Phosphotyrosine protein phosphatases I-like |Phosphotyrosine protein phosphatases I |Low-molecular-weight phosphotyrosine protein phosphatases |Tyrosine phosphatase |Human (Homo sapiens) [TaxId: 9606]
 d1c25a_ :   (LEU356)  (ASN369)   [view usage] : c.46.1.1 |Rhodanese/Cell cycle control phosphatase |Rhodanese/Cell cycle control phosphatase |Cell cycle control phosphatase, catalytic domain |CDC25a |Human (Homo sapiens) [TaxId: 9606]
 d1zkha1 :     (SER3)   (GLU16)   [view usage] : d.15.1.1 |beta-Grasp (ubiquitin-like) |Ubiquitin-like |Ubiquitin-related |Splicing factor 3 subunit 1, C-terminal domain |Human (Homo sapiens) [TaxId: 9606]
 d1zaba1 :   (PHE124)  (LEU133)   [view usage] : c.97.1.1 |Cytidine deaminase-like |Cytidine deaminase-like |Cytidine deaminase |mono-domain cytidine deaminase |Mouse (Mus musculus) [TaxId: 10090]
 d2hbvb_ :    (ASP39)   (ASP59)   [view usage] : c.1.9.15 |TIM beta/alpha-barrel |Metallo-dependent hydrolases |PP1699/LP2961-like |2-amino-3-carboxymuconate 6-semialdehyde decarboxylase NbaD |Pseudomonas fluorescens [TaxId: 294]
 d4do4b2 :   (MET347)  (ASN359)   [view usage] : b.71.1.0 |Glycosyl hydrolase domain |Glycosyl hydrolase domain |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d4jc5a_ :   (LEU197)  (ASP215)   [view usage] : d.387.1.1 |STING C-terminal-like |STING, TM173 CTD-like |Tyrosinase cofactor MelC1 |automated matches |Mouse (Mus musculus) [TaxId: 10090]
 d3p31d_ :    (ARG83)   (SER94)   [view usage] : d.299.1.1 |Ns1 effector domain-like |Ns1 effector domain-like |Ns1 effector domain-like |automated matches |Influenza A virus [TaxId: 680789]
 d1o5wa2 :   (PRO299)  (ASP319)   [view usage] : d.16.1.5 |FAD-linked reductases, C-terminal domain |FAD-linked reductases, C-terminal domain |L-aminoacid/polyamine oxidase |Monoamine oxidase B |Norway rat (Rattus norvegicus) [TaxId: 10116]
 d1a7aa1 :   (ARG334)  (ALA350)   [view usage] : c.2.1.4 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |Formate/glycerate dehydrogenases, NAD-domain |S-adenosylhomocystein hydrolase |Human (Homo sapiens) [TaxId: 9606]
 d1ou0a_ :    (LEU52)   (GLY70)   [view usage] : c.23.17.1 |Flavodoxin-like |Precorrin-8X methylmutase CbiC/CobH |Precorrin-8X methylmutase CbiC/CobH |Precorrin-8x methylmutase related protein |Thermoplasma acidophilum [TaxId: 2303]
 d2alma1 :     (THR9)   (GLY31)   [view usage] : c.95.1.1 |Thiolase-like |Thiolase-like |Thiolase-related |Beta-ketoacyl-ACP synthase II |Pneumococcus (Streptococcus pneumoniae) [TaxId: 1313]
 d3igsa_ :   (TRP202)  (SER229)   [view usage] : c.1.2.0 |TIM beta/alpha-barrel |Ribulose-phoshate binding barrel |automated matches |automated matches |Salmonella typhimurium [TaxId: 90371]
 d1aa6a2 :   (LEU523)  (THR540)   [view usage] : c.81.1.1 |Formate dehydrogenase/DMSO reductase, domains 1-3 |Formate dehydrogenase/DMSO reductase, domains 1-3 |Formate dehydrogenase/DMSO reductase, domains 1-3 |Formate dehydrogenase H |Escherichia coli [TaxId: 562]
 d4tlpa_ :    (PRO92)  (VAL119)   [view usage] : b.42.4.1 |beta-Trefoil |STI-like |Kunitz (STI) inhibitors |automated matches |Winged bean (Psophocarpus tetragonolobus) [TaxId: 3891]
 d2akja4 :   (ARG179)  (GLU193)   [view usage] : d.134.1.1 |Nitrite and sulphite reductase 4Fe-4S domain-like |Nitrite and sulphite reductase 4Fe-4S domain-like |Nitrite and sulphite reductase 4Fe-4S domain-like |Ferredoxin--nitrite reductase, NIR |Spinach (Spinacia oleracea) [TaxId: 3562]
 d1ng9a3 :   (ARG194)  (GLU205)   [view usage] : c.55.6.1 |Ribonuclease H-like motif |DNA repair protein MutS, domain II |DNA repair protein MutS, domain II |DNA repair protein MutS, domain II |Escherichia coli [TaxId: 562]
 d2j3wf_ :   (THR168)  (GLY187)   [view usage] : d.278.1.2 |Ligand-binding domain in the NO signalling and Golgi transport |Ligand-binding domain in the NO signalling and Golgi transport |TRAPP components |TRAPPC5, similar to trafficking protein particle complex 5 |Zebrafish (Danio rerio) [TaxId: 7955]
 d3h1hd1 :    (CYS40)   (THR55)   [view usage] : a.3.1.3 |Cytochrome c |Cytochrome c |Cytochrome bc1 domain |automated matches |Chicken (Gallus gallus) [TaxId: 9031]
 d1y82a1 :   (GLY127)  (LEU148)   [view usage] : c.120.1.1 |PIN domain-like |PIN domain-like |PIN domain |Hypothetical protein PF0355 |Pyrococcus furiosus [TaxId: 2261]
 d1hg3a_ :   (ASP139)  (THR151)   [view usage] : c.1.1.1 |TIM beta/alpha-barrel |Triosephosphate isomerase (TIM) |Triosephosphate isomerase (TIM) |Triosephosphate isomerase |Pyrococcus woesei [TaxId: 2262]
 d2rq9a_ :    (GLY57)   (PHE80)   [view usage] : b.42.1.1 |beta-Trefoil |Cytokine |Fibroblast growth factors (FGF) |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d3nxqb_ :   (ARG245)  (ILE264)   [view usage] : d.92.1.0 |Zincin-like |Metalloproteases ("zincins"), catalytic domain |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1b3ra1 :   (HIS333)  (ALA349)   [view usage] : c.2.1.4 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |Formate/glycerate dehydrogenases, NAD-domain |S-adenosylhomocystein hydrolase |Norway rat (Rattus norvegicus) [TaxId: 10116]
 d1b43a2 :   (LYS205)  (LYS219)   [view usage] : c.120.1.2 |PIN domain-like |PIN domain-like |5' to 3' exonuclease catalytic domain |Flap endonuclease-1 (Fen-1 nuclease) |Pyrococcus furiosus [TaxId: 2261]
 d1j3na1 :   (VAL228)  (GLY248)   [view usage] : c.95.1.1 |Thiolase-like |Thiolase-like |Thiolase-related |Beta-ketoacyl-ACP synthase II |Thermus thermophilus [TaxId: 274]
 d1i39a_ :    (THR59)   (ARG72)   [view usage] : c.55.3.1 |Ribonuclease H-like motif |Ribonuclease H-like |Ribonuclease H |Class II ribonuclease H (RNase HII) |Archaeoglobus fulgidus [TaxId: 2234]
 d2e11a_ :   (GLU234)  (ARG252)   [view usage] : d.160.1.0 |Carbon-nitrogen hydrolase |Carbon-nitrogen hydrolase |automated matches |automated matches |Xanthomonas campestris pv. campestris [TaxId: 340]
 d2dy7a1 :   (ILE183)  (ASN210)   [view usage] : b.34.13.2 |SH3-like barrel |Chromo domain-like |Chromo domain |ATP-dependent helicase CHD1 (Chromo domain protein 1) |Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]
 d4kqwa1 :   (VAL135)  (GLY154)   [view usage] : c.2.1.0 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |automated matches |automated matches |Slackia exigua [TaxId: 649764]
 d3q58b_ :   (TRP202)  (VAL224)   [view usage] : c.1.2.0 |TIM beta/alpha-barrel |Ribulose-phoshate binding barrel |automated matches |automated matches |Salmonella enterica [TaxId: 90370]
 d2gtia1 :    (GLU38)   (ARG61)   [view usage] : c.66.1.48 |S-adenosyl-L-methionine-dependent methyltransferases |S-adenosyl-L-methionine-dependent methyltransferases |Nsp15 N-terminal domain-like |Nsp15 |Murine hepatitis virus, MHV [TaxId: 11138]
 d2ifva_ :   (LEU398)  (GLY412)   [view usage] : c.46.1.1 |Rhodanese/Cell cycle control phosphatase |Rhodanese/Cell cycle control phosphatase |Cell cycle control phosphatase, catalytic domain |CDC25b |Human (Homo sapiens) [TaxId: 9606]
 d1gmya_ :     (ALA3)   (TRP11)   [view usage] : d.3.1.1 |Cysteine proteinases |Cysteine proteinases |Papain-like |(Pro)cathepsin B |Human (Homo sapiens) [TaxId: 9606]
 d2gtha1 :    (GLU38)   (ARG61)   [view usage] : c.66.1.48 |S-adenosyl-L-methionine-dependent methyltransferases |S-adenosyl-L-methionine-dependent methyltransferases |Nsp15 N-terminal domain-like |Nsp15 |Murine hepatitis virus, MHV [TaxId: 11138]
 d2a4ha1 :    (ARG70)   (ALA86)   [view usage] : c.47.1.23 |Thioredoxin fold |Thioredoxin-like |Selenoprotein W-related |Selenoprotein sep15 |Fruit fly (Drosophila melanogaster) [TaxId: 7227]
 d3zlfc2 :   (VAL421)  (LYS434)   [view usage] : c.1.11.0 |TIM beta/alpha-barrel |Enolase C-terminal domain-like |automated matches |automated matches |Streptococcus pyogenes [TaxId: 286636]
 d1o6aa_ :   (THR140)  (GLU154)   [view usage] : b.139.1.1 |Surface presentation of antigens (SPOA) |Surface presentation of antigens (SPOA) |Surface presentation of antigens (SPOA) |Putative flagelar motor switch protein FliN |Thermotoga maritima [TaxId: 2336]
 d1gsaa2 :   (ARG193)  (ASP206)   [view usage] : d.142.1.1 |ATP-grasp |Glutathione synthetase ATP-binding domain-like |ATP-binding domain of peptide synthetases |Prokaryotic glutathione synthetase, C-domain |Escherichia coli [TaxId: 562]
 d3qgva1 :   (ASN110)  (VAL134)   [view usage] : c.1.8.1 |TIM beta/alpha-barrel |(Trans)glycosidases |Amylase, catalytic domain |automated matches |Pyrococcus woesei [TaxId: 2262]

List of distinct SCOP folds where this concept is used (in one or more of its domains):
  b.68,    b.70,     e.8,     c.1,    c.10,    b.82,    c.69,    b.81,    c.81,    c.94,     c.2,     c.6,    d.58,    b.69,     i.1,    b.29,    c.26,    b.30,    b.47,    c.66,  
d.92, c.124, b.50, c.23, d.144, c.37, c.47, c.55, c.95, d.3, b.2, b.85, d.32, b.122, d.160, b.1, c.78, d.108, c.97, d.20,
d.110, b.96, b.42, d.278, c.61, c.120, d.134, d.142, b.34, d.299, a.3, d.15, d.16, b.88, a.55, c.46, d.175, b.71, d.120, c.44,
b.66, d.313, c.22, b.8, d.387, d.115, b.142, d.217, b.139